{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T05:02:02Z","timestamp":1780030922827,"version":"3.53.1"},"reference-count":22,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T00:00:00Z","timestamp":1773964800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T00:00:00Z","timestamp":1773964800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Management of acute cholecystitis (AC) in high\u2010risk surgical candidates is challenging. Drainage via percutaneous transhepatic gallbladder drainage (PT\u2010GBD) has been standard of care, with high complication and re\u2010intervention rates. Endoscopic ultrasound\u2010guided gallbladder drainage (EUS\u2010GBD) using lumen\u2010apposing metal stents (LAMS) is proposed as an alternative. This study evaluates the efficacy and safety of LAMS in EUS\u2010GBD for non\u2010surgical candidates presenting with AC.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>An institution\u2010based prospective database has tracked all patients who undergo EUS\u2010GBD using LAMS for AC. Within this database, we analysed outcomes of technical and clinical success rates, reintervention rates, adverse events, and mortality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Thirty seven patients (20 females, 17 males; mean age 74.9\u2009years) underwent EUS\u2010GBD between July 2024 and December 2025. Patients were comorbid (mean Charlson Comorbidity Index 5.7), frail (mean Clinical Frailty Scale 4.2), and had high peri\u2010operative risk (mean ASA score 3). EUS\u2010GBD was technically and clinically successful in 100% and 94.6% of cases, respectively. Two patients (5.4%) required reintervention for LAMS occlusion with recurrent AC, and one patient was re\u2010admitted with conservatively managed recurrence. Three patients died during follow up: two (5.4%) of sepsis despite intervention and one unrelated death 23\u2009days post\u2010procedure. There were no other adverse events after median follow up of 366\u2009days.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>EUS\u2010GBD with LAMS is effective and safe for non\u2010surgical candidates with AC. High success rates, coupled with low mortality and adverse events, support its role as the preferred option for drainage in non\u2010surgical candidates. Larger prospective studies are warranted to confirm these findings.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ans.70629","type":"journal-article","created":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T11:21:27Z","timestamp":1774005687000},"page":"1248-1253","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Endoscopic Ultrasound\u2010Guided Gallbladder Drainage Using Lumen\u2010Apposing Metal Stents for Non\u2010Surgical Candidates With Cholecystitis: A Prospective Cohort Study"],"prefix":"10.1111","volume":"96","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-1624-7128","authenticated-orcid":false,"given":"Tara","family":"Fox","sequence":"first","affiliation":[{"name":"Department of Gastroenterology and Hepatology Waikato Hospital  Hamilton New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Chieng","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Waikato Hospital  Hamilton New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Dalkie","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Waikato Hospital  Hamilton New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jerry Yung\u2010Lun","family":"Chin","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Waikato Hospital  Hamilton New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Fockens","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Waikato Hospital  Hamilton New Zealand"},{"name":"Gastroenterology and Hepatology, Amsterdam UMC University of Amsterdam  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Weilert","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Waikato Hospital  Hamilton New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,20]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1055\/a-1020-3932"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.21037\/dmr-20-68"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics13040657"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2023.10.043"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000006741"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2025.07.025"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2019-319996"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-020-07409-7"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.4103\/EUS-D-20-00130"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-016-5011-x"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-001-1247-4"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/jhbp.504"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-015-2747-x"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/17562848251375376"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgh.15688"},{"issue":"2","key":"e_1_2_12_17_1","first-page":"S435","article-title":"EUS\u2010Guided Gallbladder Drainage in High\u2010Surgical Risk Patients With Acute Cholecystitis and Gallbladder Perforation","volume":"56","author":"Marx M.","year":"2024","journal-title":"Endoscopy"},{"issue":"2","key":"e_1_2_12_18_1","article-title":"Outcomes of EUS\u2010Guided Gallbladder Drainage in Acute Cholecystitis With Contained Perforation: A Prospective Cohort","volume":"57","author":"Vanella G.","year":"2025","journal-title":"Endoscopy"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2024.03.027"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2022.12.039"},{"issue":"3","key":"e_1_2_12_21_1","first-page":"395","article-title":"EUS\u2010Guided Gallbladder Drainage in Acute Cholecystitis: Long\u2010Term Problems With Surgical Approach","volume":"73","author":"Bang J. 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