{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T19:41:14Z","timestamp":1783021274288,"version":"3.54.6"},"reference-count":25,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T00:00:00Z","timestamp":1775088000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T00:00:00Z","timestamp":1775088000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2026,6]]},"abstract":"ABSTRACT<\/jats:title>\n \n Objective<\/jats:title>\n Nephrectomy remains the cornerstone treatment for localised renal cancer (RC). The objective of this study was to assess outcomes of nephrectomy in a single regional centre.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n We conducted a retrospective cohort study of 114 patients undergoing nephrectomy with three surgeons at a regional referral centre between January 2019 and April 2024. Primary outcomes included operative time, ICU admission, and in\u2010hospital mortality. Secondary outcomes included blood loss, post\u2010operative complications, and preservation of renal function. Rurality was stratified according to the Modified Monash Model (MMM) rurality classification. Statistical analyses included chi\u2010square, t\u2010tests, Spearman correlation, and multivariate regression.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Of the cohort, 71.9% underwent laparoscopic and 28.1% underwent open nephrectomy. The open group had significantly longer operative time (217.5 vs. 180.0\u2009min;\n p<\/jats:italic>\n \u2009<\u20090.0001), higher blood loss (535.0 vs. 50.0\u2009mL;\n p<\/jats:italic>\n \u2009<\u20090.0002), and lower Day 1 post\u2010op Hb (109.0 vs. 119.0\u2009g\/L;\n p<\/jats:italic>\n \u2009=\u20090.03). On multivariate regression, blood loss (\n p<\/jats:italic>\n \u2009=\u20090.03) and male gender (\n p<\/jats:italic>\n \u2009=\u20090.03) independently predicted ICU admission. Age was the only significant predictor of post\u2010op complications (\n p<\/jats:italic>\n \u2009=\u20090.041). Pre\u2010op eGFR predicted post\u2010op renal function (\n p<\/jats:italic>\n \u2009<\u20090.001), and open surgery was associated with lower Day 1 eGFR (\n p<\/jats:italic>\n \u2009=\u20090.002). Rurality was not associated with worse outcomes.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Nephrectomy can be safely and effectively performed in regional centres, with outcomes comparable to metropolitan benchmarks. These findings support the provision of localised care for members of regional and rural communities.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/ans.70631","type":"journal-article","created":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T04:48:31Z","timestamp":1775191711000},"page":"1513-1520","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Evaluating Nephrectomy Outcomes in Regional Victoria: A Single\u2010Centre Cohort Study"],"prefix":"10.1111","volume":"96","author":[{"given":"Kieran","family":"Sandhu","sequence":"first","affiliation":[{"name":"University of Cambridge Cambridge UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Hennes","sequence":"additional","affiliation":[{"name":"Department of Urology Bendigo Health Bendigo Victoria Australia"},{"name":"Hudson Institute of Medical Research Clayton Victoria 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