{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T11:16:04Z","timestamp":1788347764011,"version":"build-2803163510"},"reference-count":23,"publisher":"Wiley","issue":"7-8","license":[{"start":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T00:00:00Z","timestamp":1775779200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T00:00:00Z","timestamp":1775779200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Colonic diverticulitis is a common diagnosis at emergency presentation, and traditional management includes admission, bowel rest and intravenous antibiotics. We investigated the management of patients who presented to two centres over a 2\u2010year period with acute uncomplicated diverticulitis (AUD) in the context of evidence and recent guidelines suggesting that select patients can be managed safely in the outpatient setting and without antibiotics.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Data was collected for all patients who presented to two metropolitan emergency departments from January 2023 to December 2024 with AUD. Each case was then assessed against predetermined criteria for admission, based on recent guidelines and randomised controlled trials. The primary outcome was use of antibiotics in those eligible for management without them. Secondary outcomes included IV antibiotic use and reasons for admission.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 564 patients across the two centres were included. 229 patients were deemed eligible for nonantibiotic therapy +\/\u2212 discharge. 130 of these patients were admitted; all received antibiotics. Only eight of 229 did not receive antibiotics. Outside of these 130 patients admitted without clear indication, the most common reasons for admission were sepsis, failure of outpatient therapy and age.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Most eligible patients with AUD still receive antibiotics, in both inpatient and outpatient settings, which highlights a major discrepancy between evidence\u2010based guidelines and real\u2010world practice.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ans.70677","type":"journal-article","created":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T06:50:44Z","timestamp":1775890244000},"page":"2056-2062","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Antibiotics in Uncomplicated Diverticulitis: Are we Aligning With the Evidence? A Retrospective Two\u2010Centre Study"],"prefix":"10.1111","volume":"96","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7348-8575","authenticated-orcid":false,"given":"Cameron P.","family":"Douglas","sequence":"first","affiliation":[{"name":"Department of Colorectal Surgery Prince of Wales Hospital  Sydney Australia"},{"name":"UNSW  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thi Ai Van T.","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Department of General Surgery The Sutherland Hospital  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tarkan S.","family":"Gursel","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery Prince of Wales Hospital  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica","family":"Quinlan","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery Prince of Wales Hospital  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cameron I.","family":"Law","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery Prince of Wales Hospital  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,10]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2018.12.033"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2015.302"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/1756284818791502"},{"key":"e_1_2_9_5_1","article-title":"Analysis of the Epidemiological Trends on Inpatient Diverticulosis Admissions in the US: A Longitudinal Analysis From 1997\u20132018","volume":"15","author":"Fialho A.","year":"2023","journal-title":"Cureus"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2025.103548"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e3182965a11"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13017-020-00313-4"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.15140"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000001679"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000005031"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004649900340"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.8688"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.11239"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.10309"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-019-03343-w"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2020.03.049"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-018-1817-y"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.4240\/wjgs.v9.i11.224"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-024-04701-z"},{"key":"e_1_2_9_21_1","volume-title":"AURA 2023: Fifth Australian Report on Antimicrobial Use and Resistance in Human Health","author":"Australian Commission on Safety and Quality in Health Care","year":"2023"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)02724-0"},{"key":"e_1_2_9_23_1","unstructured":"\u201cTherapeutic Guidelines. Diverticulitis. Melbourne 2024 \u201dhttps:\/\/app.tg.org.au.acs.hcn.com.au\/viewTopic?etgAccess=true&guidelinePage=Antibiotic&topicfile=bartonella\u2010infections&guidelinename=auto&sectionId=c_ABG_Diverticulitis_topic_6#c_ABG_Diverticulitis_topic_6."},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12873-022-00584-x"}],"container-title":["ANZ Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ans.70677","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ans.70677","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ans.70677","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T10:34:05Z","timestamp":1788345245000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ans.70677"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,10]]},"references-count":23,"journal-issue":{"issue":"7-8","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["10.1111\/ans.70677"],"URL":"https:\/\/doi.org\/10.1111\/ans.70677","archive":["Portico"],"relation":{},"ISSN":["1445-1433","1445-2197"],"issn-type":[{"value":"1445-1433","type":"print"},{"value":"1445-2197","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,10]]},"assertion":[{"value":"2025-11-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-07","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-10","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}