{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T12:04:35Z","timestamp":1790251475507,"version":"4.1.0"},"reference-count":55,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T00:00:00Z","timestamp":1780963200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T00:00:00Z","timestamp":1780963200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>The present study aims to evaluate the current data regarding the clinical outcomes of patients undergoing pelvic exenteration with major vascular resection and reconstruction.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study was conducted according to the PRISMA guidelines and the Cochrane handbook. Scholar databases were systematically screened. The last search date was March 2026. The primary endpoint was the overall complications rate. Secondary endpoints included specific postoperative complications, oncological outcomes of interest, and perioperative efficacy metrics. Random Effects (RE) models were reported.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Overall, 6 studies and 69 patients were included in this study. Pooled complications rate was 57.9% (95% CI: 32.2%\u201383.6%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.003). Overall vessel thrombosis and reoperation rates were estimated to be 16.5% (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.008) and 21.7% (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.011). The reported reoperated cases included hemostasis n:13, stent placement n:3, thrombectomy n:2, fasciotomies n:2 and amputation n:1. R0 resection margin was achieved in 58.2% (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.002) of patients. It was shown that in cases with a primary tumor R0 rate was 50% (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.295), while in the recurrent malignancies this dropped to 42% (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.364). Two patients had local relapse at 15 and 25\u2009months while distal metastasis related mortality developed in two patients at 14 and 22\u2009months after surgery. In total, the pooled local recurrence rate was 20% (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.002).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>We estimated a significant overall morbidity burden with increased risk for loss of vascular patency and reoperation and suboptimal oncological outcomes. Despite this, cases with pelvic confined disease that require vascular reconstruction can still be amendable in curative surgery following multidisciplinary assessment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ans.70785","type":"journal-article","created":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T05:06:57Z","timestamp":1781068017000},"page":"2321-2330","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Clinical Outcomes of Patients Submitted to Pelvic Exenteration With Major Vascular Resection and Reconstruction: A Systematic Review of the Literature"],"prefix":"10.1111","volume":"96","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6622-5734","authenticated-orcid":false,"given":"Konstantinos","family":"Perivoliotis","sequence":"first","affiliation":[{"name":"Department of Colorectal Surgery The Royal Marsden NHS Foundation Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0730-3907","authenticated-orcid":false,"given":"Paris","family":"Tekkis","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery The Royal Marsden NHS Foundation Trust  London UK"},{"name":"Imperial College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0431-6657","authenticated-orcid":false,"given":"Anisha","family":"Sukha","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery The Royal Marsden NHS Foundation Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9157-9860","authenticated-orcid":false,"given":"Maximos","family":"Frountzas","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery The Royal Marsden NHS Foundation Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheng","family":"Qiu","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery The Royal Marsden NHS Foundation Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1828-1395","authenticated-orcid":false,"given":"Christos","family":"Kontovounisios","sequence":"additional","affiliation":[{"name":"Imperial College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shahnawaz","family":"Rasheed","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery The Royal Marsden NHS Foundation Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,9]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(194807)1:2<177::AID-CNCR2820010203>3.0.CO;2-A"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2012.01.031"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/bjs\/znab070"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00595-022-02635-z"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.EJSO.2021.07.013"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/JSO.28149"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.9915"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1438.2007.01140.x"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000000421"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000002528"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.14969"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/bjs\/znad407"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000001819"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.3390\/CURRONCOL30030266"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/S12893-023-02178-1"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.1001\/ARCHSURG.2009.149"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.EJSO.2021.11.007"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000000547"},{"key":"e_1_2_13_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.RADONC.2014.11.021"},{"key":"e_1_2_13_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.JVS.2006.03.001"},{"key":"e_1_2_13_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2019.07.015"},{"key":"e_1_2_13_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.15960"},{"key":"e_1_2_13_24_1","doi-asserted-by":"publisher","DOI":"10.70352\/scrj.cr.24-0001"},{"key":"e_1_2_13_25_1","doi-asserted-by":"publisher","DOI":"10.4274\/tjod.galenos.2018.66743"},{"key":"e_1_2_13_26_1","unstructured":"J. P. T.Higgins J.Thomas J.Chandler et\u00a0al. \u201cCochrane Handbook for Systematic Reviews of Interventions Version 6.5 (updated August 2024)Cochrane \u201d2024 accessed 14 May 2025 www.training.cochrane.org\/handbook."},{"key":"e_1_2_13_27_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n71"},{"key":"e_1_2_13_28_1","doi-asserted-by":"publisher","DOI":"10.46658\/JBIMES-20-08"},{"key":"e_1_2_13_29_1","doi-asserted-by":"publisher","DOI":"10.11124\/JBISRIR-D-19-00099"},{"key":"e_1_2_13_30_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2288-5-13"},{"key":"e_1_2_13_31_1","first-page":"426","article-title":"Excision of Major Blood Vessels at the Periphery of the Pelvis in Patients Receiving Pelvic Exenteration: Common and\/or Iliac Arteries and Veins 1947 to 1964","volume":"62","author":"Barber H. R.","year":"1967","journal-title":"Surgery"},{"key":"e_1_2_13_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/DCR.0b013e3181a73f48"},{"key":"e_1_2_13_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.avsg.2015.01.028"},{"key":"e_1_2_13_34_1","doi-asserted-by":"publisher","DOI":"10.5468\/ogs.22071"},{"key":"e_1_2_13_35_1","doi-asserted-by":"publisher","DOI":"10.3802\/jgo.2023.34.e21"},{"key":"e_1_2_13_36_1","doi-asserted-by":"publisher","DOI":"10.1186\/S13643-015-0004-8\/FIGURES\/5"},{"key":"e_1_2_13_37_1","doi-asserted-by":"publisher","DOI":"10.3390\/CANCERS14205058"},{"key":"e_1_2_13_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/ANS.13872"},{"key":"e_1_2_13_39_1","doi-asserted-by":"publisher","DOI":"10.1002\/JSO.24920"},{"key":"e_1_2_13_40_1","doi-asserted-by":"publisher","DOI":"10.12998\/WJCC.V10.I3.811"},{"key":"e_1_2_13_41_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000000737"},{"key":"e_1_2_13_42_1","doi-asserted-by":"publisher","DOI":"10.1007\/S00464-018-6299-5\/FIGURES\/6"},{"key":"e_1_2_13_43_1","doi-asserted-by":"publisher","DOI":"10.1245\/S10434-025-18308-3"},{"key":"e_1_2_13_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.JVS.2021.03.036"},{"key":"e_1_2_13_45_1","doi-asserted-by":"publisher","DOI":"10.1111\/CODI.17137"},{"key":"e_1_2_13_46_1","doi-asserted-by":"publisher","DOI":"10.3892\/BR.2023.1710"},{"key":"e_1_2_13_47_1","doi-asserted-by":"publisher","DOI":"10.3748\/WJG.V19.I33.5542"},{"key":"e_1_2_13_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.EJSO.2023.04.003"},{"key":"e_1_2_13_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.EJSO.2024.108308"},{"key":"e_1_2_13_50_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13304-020-00722-9"},{"key":"e_1_2_13_51_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00423-022-02585-7"},{"key":"e_1_2_13_52_1","doi-asserted-by":"publisher","DOI":"10.1002\/BJS.9192"},{"key":"e_1_2_13_53_1","doi-asserted-by":"publisher","DOI":"10.3390\/CANCERS16233906"},{"key":"e_1_2_13_54_1","doi-asserted-by":"publisher","DOI":"10.1007\/S00384-015-2270-2"},{"key":"e_1_2_13_55_1","doi-asserted-by":"publisher","DOI":"10.1111\/CODI.15834"},{"key":"e_1_2_13_56_1","doi-asserted-by":"publisher","DOI":"10.1093\/BJS\/ZNAF123"}],"container-title":["ANZ Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ans.70785","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ans.70785","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ans.70785","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T11:16:42Z","timestamp":1790248602000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ans.70785"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,9]]},"references-count":55,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1111\/ans.70785"],"URL":"https:\/\/doi.org\/10.1111\/ans.70785","archive":["Portico"],"relation":{},"ISSN":["1445-1433","1445-2197"],"issn-type":[{"value":"1445-1433","type":"print"},{"value":"1445-2197","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,9]]},"assertion":[{"value":"2025-07-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-01","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-09","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}