{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T12:04:58Z","timestamp":1790251498227,"version":"4.1.0"},"reference-count":17,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T00:00:00Z","timestamp":1781136000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T00:00:00Z","timestamp":1781136000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Chronic kidney disease (CKD) is a common comorbidity that may impact surgical outcomes in colorectal cancer (CRC).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study evaluated the prognostic significance of CKD on postoperative complications and survival in CRC patients undergoing curative surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This retrospective cohort study included 510 patients with stage I\u2013III CRC who underwent surgery between 2011 and 2023. Patients were categorized into CKD (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200932, 81.3% had end\u2010stage renal disease) and non\u2010CKD (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009478) groups. Propensity score matching (PSM) was performed to adjust for confounders. Short\u2010term outcomes, including postoperative morbidity, in\u2010hospital mortality, and hospital stay, were analyzed alongside long\u2010term survival.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Patients with CKD exhibited significantly higher rates of surgical site infections (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.031), intra\u2010abdominal abscesses (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.047), pulmonary thromboembolism (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.021), and stroke (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.003). CKD was associated with an increased risk of severe complications (50% vs. 17.2%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and higher in\u2010hospital mortality (18.8% vs. 0.8%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). After PSM, in\u2010hospital mortality (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.024) and Clavien\u2013Dindo grade \u2265\u20093 morbidity (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.001) remained significantly higher in CKD patients. CKD did not impact disease\u2010free survival, but it was independently associated with mortality (HR: 3.262, 95% CI: 1.535\u20136.930,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.002)\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>CKD, particularly in dialysis\u2010dependent patients, significantly increases postoperative morbidity and mortality following CRC surgery. Although oncologically appropriate surgery is feasible in CKD patients, their reduced OS underscores the need for meticulous perioperative management and individualized treatment strategies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ans.70790","type":"journal-article","created":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T05:42:29Z","timestamp":1781242949000},"page":"2585-2592","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Prognostic Implications of Chronic Kidney Disease in Colorectal Cancer Surgery: A Propensity Score\u2010Matched Analysis"],"prefix":"10.1111","volume":"96","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3786-0907","authenticated-orcid":false,"given":"Afig","family":"Gojayev","sequence":"first","affiliation":[{"name":"Department of General Surgery Ba\u015fkent University School of Medicine  Ankara 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