{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T12:04:32Z","timestamp":1790251472099,"version":"4.1.0"},"reference-count":31,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T00:00:00Z","timestamp":1787184000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T00:00:00Z","timestamp":1787184000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Pelvic exenteration is an extensive procedure for advanced or recurrent pelvic malignancies, associated with high morbidity and mortality. Malnutrition is common in this cohort and may affect postoperative outcomes, but the current evidence remains inconsistent.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>A systematic review was performed following PRISMA guidelines. Pooled analyses were used to assess the relationship between preoperative nutritional status (serum albumin, BMI, and Subjective Global Assessment (SGA)) and postoperative outcomes, with results shown as odds ratios (ORs) and 95% confidence intervals (CIs).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Nine retrospective cohorts comprising 1057 patients were included. The median age across studies was 56\u2009years. Primary tumour types included colorectal, gynaecological, bladder, and soft tissue sarcoma. All studies reported complications, most of which were classified using the Clavien\u2013Dindo system. Low BMI was linked to increased postoperative morbidity (OR 1.12, 95% CI 1.02\u20131.23, *\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.02). Hypoalbuminemia (&lt; 35\u2009g\/L) (OR 1.38, 95% CI 0.62\u20133.08,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.44) and SGA\u2010defined malnutrition (OR 1.24, 95% CI 0.24\u20136.48,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.09) showed non\u2010significant but consistent trends towards higher complications in malnourished patients. Secondary outcomes were statistically significant, with malnourished patients experiencing longer hospital stays (SMD 0.44, 95% CI 0.26\u20130.62, *\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.00001) and more reoperations (OR 1.82, 95% CI 1.08\u20133.09, *\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.03).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Pre\u2010operative malnutrition is linked to increased morbidity after pelvic exenteration. Low BMI was associated with increased postoperative morbidity following pelvic exenteration, while hypoalbuminaemia and SGA\u2010defined malnutrition demonstrated consistent but non\u2010significant associations. These findings support routine nutritional screening and preoperative optimisation in this high\u2010risk patient group.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ans.70896","type":"journal-article","created":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T02:06:26Z","timestamp":1787277986000},"page":"2331-2338","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of Pre\u2010Operative Nutritional Status on Postoperative Outcomes Following Pelvic Exenteration: A Systematic Review and Meta\u2010Analysis"],"prefix":"10.1111","volume":"96","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-2638-4791","authenticated-orcid":false,"given":"Lorcan","family":"Byrne","sequence":"first","affiliation":[{"name":"Trinity St. James's Cancer Institute, St. James's Hospital  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2302-6778","authenticated-orcid":false,"given":"Cian","family":"Keogh","sequence":"additional","affiliation":[{"name":"Department of Surgery Royal Brisbane and Women's Hospital  Brisbane Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9581-9750","authenticated-orcid":false,"given":"Craig","family":"Harris","sequence":"additional","affiliation":[{"name":"Department of Surgery Royal Brisbane and Women's Hospital  Brisbane Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eamon","family":"Francis","sequence":"additional","affiliation":[{"name":"Trinity St. James's Cancer Institute, St. James's Hospital  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina","family":"Buckley","sequence":"additional","affiliation":[{"name":"Trinity St. James's Cancer Institute, St. James's Hospital  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Lonergan","sequence":"additional","affiliation":[{"name":"Trinity St. James's Cancer Institute, St. James's Hospital  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8229-9197","authenticated-orcid":false,"given":"Louise","family":"McLoughlin","sequence":"additional","affiliation":[{"name":"Trinity St. James's Cancer Institute, St. James's Hospital  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9598-8650","authenticated-orcid":false,"given":"Feras Abu","family":"Saadeh","sequence":"additional","affiliation":[{"name":"Trinity St. James's Cancer Institute, St. James's Hospital  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0757-6411","authenticated-orcid":false,"given":"Michael","family":"Kelly","sequence":"additional","affiliation":[{"name":"Trinity St. James's Cancer Institute, St. James's Hospital  Dublin Ireland"},{"name":"Department of Surgery University of Dublin \u2013 Trinity College Dublin  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8209-4810","authenticated-orcid":false,"given":"Ben","family":"Creavin","sequence":"additional","affiliation":[{"name":"Trinity St. James's Cancer Institute, St. James's Hospital  Dublin Ireland"},{"name":"Department of Surgery Royal Brisbane and Women's Hospital  Brisbane Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,20]]},"reference":[{"key":"e_1_2_10_2_1","volume-title":"StatPearls [Internet]","author":"Grimes W. 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