{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T04:28:22Z","timestamp":1793593702291,"version":"4.5.0"},"reference-count":31,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T00:00:00Z","timestamp":1788912000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T00:00:00Z","timestamp":1788912000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Splenectomy has traditionally been used to treat a range of haematological diseases. Advances in medical therapies and minimally invasive surgery have altered its therapeutic role. This study evaluates evolving indications and outcomes of elective splenectomy in an Australian teaching hospital over a 27\u2010year period.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Adult patients undergoing elective splenectomy for haematological disease between 1999 and 2025 at a single tertiary institution were identified from medical records. Caseload, demographics, operative approach, complications and follow\u2010up outcomes were assessed either annually or over three 9\u2010year cohorts. Regression and Fisher's exact tests were used for trend analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Seventy patients underwent splenectomy. The annualised caseload and cohort patient age decreased significantly over the study period (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.005 and 0.020, respectively). Benign indications accounted for 54% of patients, most commonly immune thrombocytopenia, while lymphoma and myelofibrosis predominated among malignant indications. There was an upward trend for laparoscopic splenectomy over time (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.051), reduced conversion rates (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.189) and a decrease in operative time (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.012). The overall post\u2010operative complication rate was 21.4%, and most were minor. Ninety\u2010day post\u2010operative mortality was zero. The median follow\u2010up was 9.1\u2009years. Long\u2010term survival was primarily influenced by underlying haematologic disease, with most long\u2010term survivors well with normal platelet counts.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Despite declining referrals in the era of targeted therapies, splenectomy remains a safe and effective treatment option in selected patients. Outcomes are favourable when performed laparoscopically in experienced hands, and long\u2010term follow\u2010up demonstrates sustained haematologic benefit in surviving patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ans.70961","type":"journal-article","created":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T01:15:59Z","timestamp":1789002959000},"page":"3116-3125","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Long\u2010Term Outcomes After Elective Splenectomy for Haematological Disease: A 27\u2010Year Single\u2010Centre Study"],"prefix":"10.1111","volume":"96","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-2459-353X","authenticated-orcid":false,"given":"Salil Dutt","family":"Barrett","sequence":"first","affiliation":[{"name":"Sydney Medical School University of Sydney  Sydney New South Wales 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