{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T23:11:28Z","timestamp":1785193888994,"version":"3.55.0"},"reference-count":32,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,3,21]],"date-time":"2013-03-21T00:00:00Z","timestamp":1363824000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2013,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Abnormally invasive placenta (<jats:styled-content style=\"fixed-case\">AIP<\/jats:styled-content>) poses diagnostic and therapeutic challenges. We analyzed clinical cases with confirmed placenta increta or percreta.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Retrospective case series.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Multicenter study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Population<\/jats:title><jats:p>Pregnant women with <jats:styled-content style=\"fixed-case\">AIP<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Chart review.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measures<\/jats:title><jats:p>Prenatal detection rates, treatment choices, morbidity, mortality and short\u2010term outcome.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Sixty\u2010six cases were analyzed. All women and all but three fetuses survived; 57\/64 women (89%) had previous uterine surgery. In 26 women (39%) the diagnosis was not known before delivery (Group 1), in the remaining 40 (61%) diagnosis had been made between 14 and 37\u00a0weeks of gestation (Group 2). Placenta previa was present in 36 women (54%). In Groups 1 and 2, 50% (13\/26) and 62% (25\/40) of the women required hysterectomy, respectively. In Group 1 (unknown at the time of delivery) 69% (9\/13) required (emergency) hysterectomy for severe hemorrhage in the immediate peripartum period compared with only 12% (3\/25) in Group 2 (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.0004). Mass transfusions were more frequently required in Group 1 (46%, 12\/26 vs. 20%, 8\/40; <jats:italic>p<\/jats:italic>\u00a0=\u00a00.025). In 18\/40 women (45%) from Group 2 the placenta was intentionally left in situ; secondary hysterectomies and infections were equally frequent (18%) among these differently treated women. Overall, postpartum infections occurred in 11% and 20% of women in Groups 1 and 2, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">AIP<\/jats:styled-content> was known before delivery in more than half of the cases. Unknown <jats:styled-content style=\"fixed-case\">AIP<\/jats:styled-content> led to significantly more emergency hysterectomies and mass transfusions during or immediately after delivery. Prenatal diagnosis of <jats:styled-content style=\"fixed-case\">AIP<\/jats:styled-content> reduces morbidity. Future studies should also address the selection criteria for cases appropriate for leaving the placenta in situ.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aogs.12081","type":"journal-article","created":{"date-parts":[[2013,1,19]],"date-time":"2013-01-19T08:02:50Z","timestamp":1358582570000},"page":"439-444","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":88,"title":["Prenatal diagnosis of abnormally invasive placenta reduces maternal peripartum hemorrhage and morbidity"],"prefix":"10.1111","volume":"92","author":[{"given":"Fr\u00e9d\u00e9ric","family":"Chantraine","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology CHR Citadelle Li\u00e8ge Belgium"},{"name":"Laboratory of Tumor and Development Biology, CHU, GIGA\u2010Cancer University of Li\u00e8ge Li\u00e8ge Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thorsten","family":"Braun","sequence":"additional","affiliation":[{"name":"Charit\u00e9 Campus Virchow Department of Obstetrics University Hospital Berlin Berlin Germany"},{"name":"Division of Perinatal Programming Charit\u00e9 Campus Virchow Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markus","family":"Gonser","sequence":"additional","affiliation":[{"name":"Horst Schmidt Kliniken Wiesbaden Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolfgang","family":"Henrich","sequence":"additional","affiliation":[{"name":"Charit\u00e9 Campus Virchow Department of Obstetrics University Hospital Berlin Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boris","family":"Tutschek","sequence":"additional","affiliation":[{"name":"Center for Fetal Medicine and Gynecological Ultrasound Basel Switzerland"},{"name":"Heinrich Heine University D\u00fcsseldorf Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,3,21]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(96)70117-5"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2010.09.013"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(97)70463-0"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ogx.0000271133.27011.05"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.2008.055202"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000207559.15715.98"},{"key":"e_1_2_10_8_1","volume-title":"UpToDate","author":"Resnik R","year":"2011"},{"key":"e_1_2_10_9_1","first-page":"89","article-title":"Placenta previa\/accreta and prior cesarean section","volume":"66","author":"Clark SL","year":"1985","journal-title":"Obstet Gynecol."},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2004.12.074"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(00)01028-0"},{"key":"e_1_2_10_12_1","first-page":"474","article-title":"First\u2010trimester uterine rupture from a placenta percreta. 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