{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,17]],"date-time":"2026-05-17T06:13:05Z","timestamp":1778998385534,"version":"3.51.4"},"reference-count":22,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2013,3,12]],"date-time":"2013-03-12T00:00:00Z","timestamp":1363046400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2013,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To measure adherence to annual follow\u2010up among women treated for cervical intraepithelial neoplasia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Prospective, population\u2010based, register study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Denmark, 1996\u20132007.<\/jats:p><\/jats:sec><jats:sec><jats:title>Population<\/jats:title><jats:p>All women treated for cervical intraepithelial neoplasia with conization.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Treated women were routinely recommended to have follow\u2010up with annual smears for at least 5\u00a0years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measures<\/jats:title><jats:p>Using individually linked nationwide register data on conizations and follow\u2010up tests (smears and biopsies), we calculated the cumulative proportion of treated women undergoing the recommended follow\u2010up. We measured this cumulative proportion conservatively in 15\u2010month intervals for 5\u00a0years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Adherence to annual follow\u2010up among 45\u00a0984 treated women decreased gradually. In total, 90% of these women obtained at least one smear in the first post\u2010treatment year, but only 40% obtained the recommended tests for 5\u00a0years. Five\u2010year adherence was substantially better outside the capital area, for example, the odds ratio for women from Jutland compared with women from the capital area was 1.70 (95% confidence interval 1.60\u20131.82).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Adherence to follow\u2010up after conization was poor in Denmark. Our findings suggest that because of this poor adherence, recommendations for long\u2010term annual follow\u2010up after treatment of cervical intraepithelial neoplasia may not be highly effective. Shorter follow\u2010up schedules using highly sensitive tests appear attractive.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aogs.12116","type":"journal-article","created":{"date-parts":[[2013,2,19]],"date-time":"2013-02-19T16:17:15Z","timestamp":1361290635000},"page":"852-857","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Long\u2010term adherence to follow\u2010up after treatment of cervical intraepithelial neoplasia: nationwide population\u2010based study"],"prefix":"10.1111","volume":"92","author":[{"given":"Sidsel S.","family":"Barken","sequence":"first","affiliation":[{"name":"Department of Public Health University of Copenhagen Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elsebeth","family":"Lynge","sequence":"additional","affiliation":[{"name":"Department of Public Health University of Copenhagen Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erik S.","family":"Andersen","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics Aalborg Hospital Aalborg Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matejka","family":"Rebolj","sequence":"additional","affiliation":[{"name":"Department of Public Health University of Copenhagen Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,3,12]]},"reference":[{"key":"e_1_2_9_2_1","volume-title":"IARC handbooks of cancer prevention, vol. 10: cervix cancer screening","author":"International Agency for Research on Cancer","year":"2005"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(96)08295-5"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.21604"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.39363.471806.BE"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djp089"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.39364.439444.80"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2006.05.020"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2001.00240.x"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1159\/000332695"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(01)01526-5"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.3109\/02813438809009288"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/1403494811401482"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/1403494810394718"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/1403494810393563"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1177\/1403494810393562"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/1403494810387965"},{"key":"e_1_2_9_18_1","first-page":"5783","article-title":"Slyngekonisering af cervix uteri i gyn\u00e6kologisk speciall\u00e6gepraksis [Loop conization of cervix uteri in gynecological practice] (in Danish)","volume":"160","author":"Nellemann G","year":"1998","journal-title":"Ugeskr Laeg"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.26248"},{"key":"e_1_2_9_20_1","unstructured":"Sundhedsstyrelsen.Screening for livmoderhalskr\u00e6ft \u2013 anbefalinger 2012[Screening for cervical cancer \u2013 2012 recommendations] (in Danish). Available online at:http:\/\/www.sst.dk\/publ\/Publ2012\/SYB\/Kraeft\/ScreenLivmoderhalskrftAnbef.pdf. (accessed 12 March 2012)."},{"key":"e_1_2_9_21_1","unstructured":"NHS Cervical Screening Programme.HPV triage and test of cure protocol. Available online at:http:\/\/www.cancerscreening.nhs.uk\/cervical\/hpv-triage-test-of-cure.html. (accessed 25 August 2011)."},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2008.01748.x"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(11)70078-X"}],"container-title":["Acta Obstetricia et Gynecologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Faogs.12116","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aogs.12116","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,22]],"date-time":"2023-11-22T10:31:04Z","timestamp":1700649064000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/aogs.12116"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,3,12]]},"references-count":22,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2013,7]]}},"alternative-id":["10.1111\/aogs.12116"],"URL":"https:\/\/doi.org\/10.1111\/aogs.12116","archive":["Portico"],"relation":{},"ISSN":["0001-6349","1600-0412"],"issn-type":[{"value":"0001-6349","type":"print"},{"value":"1600-0412","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,3,12]]},"assertion":[{"value":"2012-03-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-02-08","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-03-12","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}