{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T21:23:08Z","timestamp":1791235388709,"version":"4.1.0"},"reference-count":26,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,3,29]],"date-time":"2013-03-29T00:00:00Z","timestamp":1364515200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2013,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To investigate asymptomatic shedding from the uterine cervix of five human herpes viruses: cytomegalovirus (<jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content>), Epstein\u2013Barr virus (<jats:styled-content style=\"fixed-case\">EBV<\/jats:styled-content>), herpes simplex virus (<jats:styled-content style=\"fixed-case\">HSV<\/jats:styled-content>) type 1 and type 2 and varicella zoster virus (<jats:styled-content style=\"fixed-case\">VZV<\/jats:styled-content>), in young women.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>A descriptive study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Sahlgrenska University Hospital.<\/jats:p><\/jats:sec><jats:sec><jats:title>Population<\/jats:title><jats:p>Three hundred and five young, healthy Swedish women.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Cervical specimens were analyzed for the presence of viral <jats:styled-content style=\"fixed-case\">DNA<\/jats:styled-content> with a quantitative real\u2010time <jats:styled-content style=\"fixed-case\">PCR<\/jats:styled-content> assay.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measures<\/jats:title><jats:p>Detection of viral <jats:styled-content style=\"fixed-case\">DNA<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Viral DNA was detected in 66 (21.6%) of the cervical samples. The most common findings were CMV DNA, detected in 35 (11.5%), and EBV DNA, found in 32 (10.5%) of the women. HSV\u20101 DNA was detected in 5 (1.7%) and HSV\u20102 DNA in 4 (1.4%), but VZV DNA was not found. The estimated DNA level for the detected viruses was similar with a mean DNA quantity of 2.6 log genome equivalents (Geq)\/mL for CMV (range 1.7\u20134.3), 2.5 log Geq\/mL for EBV (range 1.7\u20134.7), 2.4 log Geq\/mL for HSV\u20101 (range 1.7\u20133.5) and 2.6 log Geq\/mL for HSV\u20102 (range 1.7\u20134.1). The simultaneous presence of DNA from two or more herpes viruses was detected in eight specimens.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Asymptomatic shedding of <jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">EBV<\/jats:styled-content> from the uterine cervix was found in one\u2010fifth of young women. In four of the cervical samples; two with <jats:styled-content style=\"fixed-case\">EBV<\/jats:styled-content>, one with <jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content>, one with <jats:styled-content style=\"fixed-case\">HSV<\/jats:styled-content>\u20102, high amounts of viral <jats:styled-content style=\"fixed-case\">DNA<\/jats:styled-content> (&gt;4 log\u00a0Geq\/mL) were detected suggesting a greater risk of transmitting the virus perinatally or sexually.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aogs.12134","type":"journal-article","created":{"date-parts":[[2013,3,29]],"date-time":"2013-03-29T08:28:34Z","timestamp":1364545714000},"page":"706-710","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Frequent detection of cytomegalovirus and Epstein\u2013Barr virus in cervical secretions from healthy young women"],"prefix":"10.1111","volume":"92","author":[{"given":"Matilda","family":"Berntsson","sequence":"first","affiliation":[{"name":"Department of Dermatology and Venereology Sahlgrenska University Hospital Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lejla","family":"Dubicanac","sequence":"additional","affiliation":[{"name":"Department ofClinical Virology Sahlgrenska University Hospital Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petra","family":"Tunb\u00e4ck","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology Sahlgrenska University Hospital Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agneta","family":"Ellstr\u00f6m","sequence":"additional","affiliation":[{"name":"Department ofObstetrics and Gynecology Sahlgrenska University Hospital Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gun\u2010Britt","family":"L\u00f6whagen","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology Sahlgrenska University Hospital Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomas","family":"Bergstr\u00f6m","sequence":"additional","affiliation":[{"name":"Department ofClinical Virology Sahlgrenska University Hospital Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,3,29]]},"reference":[{"key":"e_1_2_9_2_1","first-page":"401","article-title":"Konnatale Epstein\u2013Barr\u2010Virus\u2010Infektion. 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