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The aim of this study was to evaluate whether having suffered from preeclampsia (PE) or <jats:styled-content style=\"fixed-case\">HELLP<\/jats:styled-content> (hemolysis, elevated liver enzymes, and low platelets) syndrome is associated with anxiety and depression, and whether <jats:styled-content style=\"fixed-case\">PE<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">HELLP<\/jats:styled-content> is an independent risk factor for developing anxiety and depression. Systematic search on PubMed and PsycInfo with no time limit. Studies presenting original data, including women with a history of <jats:styled-content style=\"fixed-case\">PE<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">HELLP<\/jats:styled-content> and at least one comparison group of women without <jats:styled-content style=\"fixed-case\">PE<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">HELLP<\/jats:styled-content>, reporting the results for each group separately or in a multivariate regression analysis with PE\/<jats:styled-content style=\"fixed-case\">HELLP<\/jats:styled-content> as an independent variable. Study characteristics and outcomes were extracted using a prespecified form. If necessary, additional calculations were performed. The search yielded 267 articles, with only six being suitable for inclusion in this review. Studies on depression (six studies) showed generally positive associations between <jats:styled-content style=\"fixed-case\">PE<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">HELLP<\/jats:styled-content> and the prevalence of depression or severity of depressive symptoms. However, the results of three studies were not statistically significant. Studies addressing anxiety (two studies) did not show significant associations between <jats:styled-content style=\"fixed-case\">PE<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">HELLP<\/jats:styled-content> and anxiety scores. Associations between post\u2010traumatic stress and <jats:styled-content style=\"fixed-case\">PE<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">HELLP<\/jats:styled-content>, investigated in four studies, were often nonsignificant. Due to heterogeneity of study methods, a meta\u2010analysis of the results was not possible. In most studies, confounder control was poor. Evidence is mixed but generally points to positive associations between various forms of psychopathology and previous PE\/<jats:styled-content style=\"fixed-case\">HELLP<\/jats:styled-content>. Causality of the associations can, however, not be judged adequately.<\/jats:p>","DOI":"10.1111\/aogs.12175","type":"journal-article","created":{"date-parts":[[2013,5,16]],"date-time":"2013-05-16T08:09:09Z","timestamp":1368691749000},"page":"746-761","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":50,"title":["Anxiety and depression following preeclampsia or hemolysis, elevated liver enzymes, and low platelets syndrome. 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