{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T01:55:35Z","timestamp":1789437335205,"version":"build-2803163510"},"reference-count":13,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2013,9,16]],"date-time":"2013-09-16T00:00:00Z","timestamp":1379289600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2013,10]]},"abstract":"Abstract<\/jats:title>Objective<\/jats:title>The aim of this study was to describe venous thromboembolism (VTE<\/jats:styled-content>) in pregnancy and the puerperal period, and to validate diagnoses of VTE<\/jats:styled-content>.<\/jats:p><\/jats:sec>Design<\/jats:title>Historical cohort study.<\/jats:p><\/jats:sec>Population<\/jats:title>All pregnancies in Denmark from 1995 to 2009.<\/jats:p><\/jats:sec>Methods<\/jats:title>VTE<\/jats:styled-content> diagnoses were retrieved from national registries.<\/jats:p><\/jats:sec>Main outcome measures<\/jats:title>Positive predictive value of a VTE<\/jats:styled-content> diagnoses diagnosed during pregnancy or the puerperal period. Location of VTE<\/jats:styled-content>. Incidence rate of confirmed, validated diagnoses of VTE<\/jats:styled-content> and on all retrieved diagnoses of VTE<\/jats:styled-content>.<\/jats:p><\/jats:sec>Results<\/jats:title>In 1\u00a0297 037 pregnancies, 1436 women had a first\u2010ever VTE<\/jats:styled-content> diagnosis. Hospital records were retrieved for 1210 women (84.3%). Almost all women had relevant clinical symptoms and in 796 (65.8%), the diagnosis were confirmed by a positive diagnostic test or by instituted anticoagulation treatment. In all, 72.6, 53.7, 58.5 and 79.1% of the diagnoses were confirmed in the first, second, third trimester and the puerperal period, respectively. The 796 cases of VTE<\/jats:styled-content> included 624 women with deep venous thrombosis only and 133 with pulmonary embolisms. Deep venous thrombosis was located in the left lower limb in 83.8% in pregnancy, compared with 67.9% in the puerperal period.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>The vast majority of women with a registered diagnosis of VTE<\/jats:styled-content> had relevant symptoms. Diagnoses of VTE<\/jats:styled-content> were confirmed in the medical records in two of three women. VTE<\/jats:styled-content> diagnoses were most often confirmed when made in the first trimester and in the puerperal period. Left\u2010sided deep venous thrombosis was the predominant type of VTE<\/jats:styled-content> in pregnancy and the puerperal period.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aogs.12223","type":"journal-article","created":{"date-parts":[[2013,7,19]],"date-time":"2013-07-19T14:58:36Z","timestamp":1374245916000},"page":"1135-1142","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Venous thromboembolism in pregnancy and the puerperal period: a study of 1210 events"],"prefix":"10.1111","volume":"92","author":[{"given":"Rie Adser","family":"Virkus","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Hiller\u00f8d Hospital University of Copenhagen Hiller\u00f8d Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ellen C.L.","family":"L\u00f8kkegaard","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Hiller\u00f8d Hospital University of Copenhagen Hiller\u00f8d Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00d8jvind","family":"Lidegaard","sequence":"additional","affiliation":[{"name":"Gynecological Clinic Rigshospitalet University of Copenhagen Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jens","family":"Langhoff\u2010Roos","sequence":"additional","affiliation":[{"name":"Department of Obstetrics Rigshospitalet University of Copenhagen Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars","family":"Bjerregaard","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology Hiller\u00f8d Hospital University of Copenhagen Hiller\u00f8d Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotte W.","family":"Skovlund","sequence":"additional","affiliation":[{"name":"Gynecological Clinic Rigshospitalet University of Copenhagen Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Bergholt","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Hiller\u00f8d Hospital University of Copenhagen Hiller\u00f8d Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,9,16]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1160\/TH10-12-0823"},{"key":"e_1_2_10_3_1","first-page":"e1","article-title":"Incidence and risk patterns of venous thromboembolism in pregnancy and puerperium \u2013 a register\u2010based case\u2010control study","volume":"233","author":"Jacobsen AF","year":"2008","journal-title":"Am J Obstet Gynecol"},{"key":"e_1_2_10_4_1","first-page":"463","article-title":"Danish health registries. 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