{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T11:34:57Z","timestamp":1788953697201,"version":"build-2803163510"},"reference-count":34,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2013,10,15]],"date-time":"2013-10-15T00:00:00Z","timestamp":1381795200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2013,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To compare detection rates of small\u2010for\u2010gestational\u2010age fetuses, large\u2010for\u2010gestational\u2010age fetuses, congenital anomalies and adverse perinatal outcomes in pregnancies randomized to third\u2010trimester routine ultrasound or ultrasound on clinical indication.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Randomized controlled trial.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>National Center for Fetal Medicine in Norway between 1989 and 1992.<\/jats:p><\/jats:sec><jats:sec><jats:title>Population<\/jats:title><jats:p>A total of 6780 pregnancies from a non\u2010selected population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Two routine ultrasound examinations at 18 and 33\u00a0weeks were compared with routine ultrasound at 18\u00a0weeks and ultrasound on clinical indication. Suspected small\u2010for\u2010gestational\u2010age fetuses were followed with serial scans and cardiotocography. Doppler ultrasound was not used.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measures<\/jats:title><jats:p>Detection rates of small\u2010for\u2010gestational\u2010age and large\u2010for\u2010gestational\u2010age fetuses, congenital anomalies and adverse perinatal outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Third trimester routine ultrasound improved detection rates of small\u2010for\u2010gestational\u2010age fetuses from 46 to 80%, but overall perinatal morbidity and mortality remained unchanged. Detection of large\u2010for\u2010gestational\u2010age fetuses increased from 36 to 91%. There was a significant increase of induction of labor and elective cesarean sections due to suspected small\u2010for\u2010gestational\u2010age and a significant decrease of induction of labor and elective cesarean sections due to suspected large\u2010for\u2010gestational\u2010age in the study group; there were no other differences regarding intervention. The detection rate of congenital anomalies was 56%, with no significant difference between the groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Routine use of third\u2010trimester routine ultrasound increased detection rates of small\u2010for\u2010gestational\u2010age and large\u2010for\u2010gestational\u2010age fetuses. This did not alter perinatal outcomes. Third\u2010trimester ultrasound screening should not be rejected before a policy of adding Doppler surveillance to the high\u2010risk group identified has been investigated further.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aogs.12249","type":"journal-article","created":{"date-parts":[[2013,8,30]],"date-time":"2013-08-30T07:13:40Z","timestamp":1377846820000},"page":"1353-1360","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":46,"title":["A randomized controlled trial of third\u2010trimester routine ultrasound in a non\u2010selected population"],"prefix":"10.1111","volume":"92","author":[{"given":"Ragnhild B.","family":"Skr\u00e5stad","sequence":"first","affiliation":[{"name":"Faculty of Medicine Department of Laboratory Medicine Children's and Women's Health Norwegian University of Science and Technology Trondheim Norway"},{"name":"Department of Obstetrics and Gynecology National Center for Fetal Medicine St Olav's Hospital 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