{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T05:36:29Z","timestamp":1790314589317,"version":"4.1.0"},"reference-count":19,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,1,22]],"date-time":"2014-01-22T00:00:00Z","timestamp":1390348800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2014,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To identify the extent of lymphadenectomy performed in women presenting with epithelial ovarian cancer macroscopically confined to the ovary. Furthermore, the effect of lymphadenectomy on overall survival is evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>A prospective nationwide case\u2010only study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Denmark 2005\u20132011.<\/jats:p><\/jats:sec><jats:sec><jats:title>Sample<\/jats:title><jats:p>All women registered in the nationwide Danish Gynecologic Cancer Database from 1 January 2005 to 1 May 2011, presenting with a tumor macroscopically confined to the ovary without visible evidence of abdominal spread at the time of the initial exploration (surgical stage I).<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Descriptive and survival analyses of data from Danish Gynecologic Cancer Database.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measures<\/jats:title><jats:p>The annual proportion of women with surgical stage I disease who received lymphadenectomy and the survival in the two groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 2361 women with epithelial ovarian cancer, 627 were identified with surgical stage I. Lymphadenectomy was performed in 216 women (34%) of whom 13 (6%) had lymph node metastases. At 5\u2010year follow up 85% remained alive in the lymphadenectomy group compared with 80% in the control group (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.064). The lymphadenectomy fraction increased from 24% in 2005 to 55% in 2011. When univariate and multivariate analyses were conducted only an insignificant difference in the survival probability was found between lymphadenectomy and no lymphadenectomy in women presenting with tumor macroscopically confined to the ovary.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Although increasing, the number of women with surgical stage I disease in Denmark who receive lymphadenectomy remains low, but this did not seem to make a difference to survival.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aogs.12322","type":"journal-article","created":{"date-parts":[[2013,12,18]],"date-time":"2013-12-18T06:43:02Z","timestamp":1387348982000},"page":"256-260","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Lymphadenectomy in surgical stage I epithelial ovarian cancer"],"prefix":"10.1111","volume":"93","author":[{"given":"Olivia","family":"Svolgaard","sequence":"first","affiliation":[{"name":"Department of Gynecology Juliane Marie Center Copenhagen University Hospital Rigshospitalet Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00d8jvind","family":"Lidegaard","sequence":"additional","affiliation":[{"name":"Department of Gynecology Juliane Marie Center Copenhagen University Hospital Rigshospitalet Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie Louise S.","family":"Nielsen","sequence":"additional","affiliation":[{"name":"Section of Clinical Information and Data (KID) Center of Quality and Health Information East Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lotte","family":"Nedergaard","sequence":"additional","affiliation":[{"name":"Department of Pathology Center of Diagnostic investigation Copenhagen University Hospital Rigshospitalet Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Berit J.","family":"Mosgaard","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Herlev Hospital Herlev Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marianne","family":"Lidang","sequence":"additional","affiliation":[{"name":"Department of Pathology Herlev Hospital Herlev Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ole","family":"Mogensen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Odense University Hospital Odense Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kirsten","family":"Kock","sequence":"additional","affiliation":[{"name":"Department of Pathology Odense University Hospital Odense Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Blaak\u00e6r","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Skejby University Hospital Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Estrid","family":"St\u00e6hr","sequence":"additional","affiliation":[{"name":"Institute of Pathology Aarhus University Hospital Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erik S.","family":"Andersen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Aalborg University Hospital Aalborg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anni","family":"Grove","sequence":"additional","affiliation":[{"name":"Institute of Pathology Aalborg University Hospital Aalborg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claus","family":"H\u00f8gdall","sequence":"additional","affiliation":[{"name":"Department of Gynecology Juliane Marie Center Copenhagen University Hospital Rigshospitalet Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,1,22]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"Statens Serum Institut Cancerregisteret.Tal og Analyse. (in Danish. No abstract available). 2011. Available online at:http:\/\/www.ssi.dk\/Sundhedsdataogit\/Registre\/~\/media\/Indhold\/DK%20-%20dansk\/Sundhedsdata%20og%20it\/NSF\/Registre\/Cancerregisteret\/Cancerregisteret%202011.ashx(accessed July 15 2013)."},{"key":"e_1_2_9_3_1","unstructured":"Dansk Gyn\u00e6kologisk Cancer Database. [Danish Gynecological Cancer Database. Annual Report 2011]. (in Danish. No abstract available). 2012. Available online at:http:\/\/www.dgcg.dk\/images\/DGCD%20rsrapport%202011.pdf(accessed July 15 2013)."},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD004706.pub2"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCO.0b013e32834847e7"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-7292(00)90001-8"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6603323"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2006.11.022"},{"key":"e_1_2_9_9_1","unstructured":"Dansk Gyn\u00e6kologisk Cancer Gruppe.[Instructions for referral diagnostics and control of epithelial ovarian\u2010 fallopian tube\u2010 and primary peritoneal cancer plus borderline tumors 4rd ed.](in Danish. No abstract available).2012. Available online at:http:\/\/www.dgcg.dk\/images\/retningslinier\/Ovariecancer_retningslinier_finale_juli_2012.pdf(accessed July 15 2013)."},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2010.02633.x"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2009.12.012"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2012.10.011"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2012-0088"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-012-2439-7"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7819-8-106"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/GCO.0b013e3282f2fd68"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/IGC.0b013e3181b8a07c"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.12359"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.12358"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.12123"}],"container-title":["Acta Obstetricia et Gynecologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Faogs.12322","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aogs.12322","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T17:34:54Z","timestamp":1695490494000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/aogs.12322"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1,22]]},"references-count":19,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2014,3]]}},"alternative-id":["10.1111\/aogs.12322"],"URL":"https:\/\/doi.org\/10.1111\/aogs.12322","archive":["Portico"],"relation":{},"ISSN":["0001-6349","1600-0412"],"issn-type":[{"value":"0001-6349","type":"print"},{"value":"1600-0412","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,1,22]]},"assertion":[{"value":"2013-01-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-12-11","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-01-22","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}