{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T20:54:48Z","timestamp":1761252888330},"reference-count":17,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2014,4,23]],"date-time":"2014-04-23T00:00:00Z","timestamp":1398211200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2014,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To describe developments in reproductive long\u2010term prognosis in women with a first ectopic pregnancy as compared with two control cohorts.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Controlled cohort study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Data were collected from four national Danish registries.<\/jats:p><\/jats:sec><jats:sec><jats:title>Population<\/jats:title><jats:p>All Danish women of reproductive age (15\u201349\u00a0years) through the period 1977\u20132009 and all reproductive outcomes in these women.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data were collected from four national Danish registries. Three cohorts of women with a first recorded ectopic pregnancy during the periods 1980\u201384, 1985\u201389, and 1990\u201394, were compared with age\u2010matched controls with a first miscarriage and a first induced abortion and followed for 15\u00a0years for all further pregnancy outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measures<\/jats:title><jats:p>Pregnancy outcomes included deliveries, miscarriages, induced abortions and ectopic pregnancies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The birth rate for women with a first ectopic pregnancy increased significantly through the three cohorts from 85 to 122 deliveries\/100 women during the follow\u2010up period. The risk of miscarriages also increased over time, whereas the risk of further ectopic pregnancies remained unchanged at 22\u201324 events\/100 women. Compared to women with a first miscarriage, the rate ratio for deliveries increased from 0.59 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 0.56\u20130.63) to 0.71 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 0.68\u20130.75) over the time covering the three cohorts.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The long\u2010term delivery rate among women with a first ectopic pregnancy has improved significantly over time.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aogs.12377","type":"journal-article","created":{"date-parts":[[2014,3,11]],"date-time":"2014-03-11T13:29:33Z","timestamp":1394544573000},"page":"490-496","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Improving reproductive long\u2010term prognosis for women with a first ectopic pregnancy. A national controlled follow\u2010up study"],"prefix":"10.1111","volume":"93","author":[{"given":"Pia","family":"Egerup","sequence":"first","affiliation":[{"name":"Department of Gynecology Rigshospitalet University Hospital University of Copenhagen Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Line Lund","family":"K\u00e5rhus","sequence":"additional","affiliation":[{"name":"Department of Gynecology Rigshospitalet University Hospital University of Copenhagen Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charlotte Wessel","family":"Skovlund","sequence":"additional","affiliation":[{"name":"Department of Gynecology Rigshospitalet University Hospital University of Copenhagen Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00d8jvind","family":"Lidegaard","sequence":"additional","affiliation":[{"name":"Department of Gynecology Rigshospitalet University Hospital University of Copenhagen Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,4,23]]},"reference":[{"key":"e_1_2_9_2_1","first-page":"3282","article-title":"[Fertility after conservative surgical treatment of ectopic pregnancy, evaluated by a randomized trial]","volume":"155","author":"Lundorff P","year":"1993","journal-title":"Ugeskr Laeger"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.humrep.a019048"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/13.7.1804"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/13.11.3239"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-970052"},{"key":"e_1_2_9_7_1","first-page":"337","article-title":"Factors affecting fertility following radical versus conservative surgical treatment for tubal pregnancy","volume":"22","author":"Rashid M","year":"2001","journal-title":"Saudi Med J"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2000.tb13330.x"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2003.02253.x"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/des375"},{"key":"e_1_2_9_11_1","unstructured":"Sundhedsstyrelsen wsd.IVF Registeret [Registry of IVF] Sundhedsstyrelsen; [cited 1994\u2010]: [about 1 p]. 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