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Specific patterns of these proteins represent preeclamptic prediction markers and combined with maternal and clinical characteristics, the predictive values increase. Women experiencing preeclampsia have increased risks of developing cardiovascular diseases and diabetes, and a decreased risk of breast cancer. High placental growth factor concentrations have, in elderly patients, been shown to predict cardiovascular events. Diabetes is also a risk factor for future cardiovascular disease. Diabetic vascular complications are associated with increased soluble endoglin concentrations, and vascular endothelial growth factor concentrations are correlated to HbA1c and fasting glucose. Hence dysregulation in angiogenic proteins may link preeclampsia and cardiovascular diseases, targeting women who could in future benefit from prophylactic programs to possibly prevent, delay or reduce cardiovascular disease.<\/jats:p>","DOI":"10.1111\/aogs.12629","type":"journal-article","created":{"date-parts":[[2015,3,6]],"date-time":"2015-03-06T15:11:25Z","timestamp":1425654685000},"page":"820-832","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Angiogenic biomarkers in pregnancy: defining maternal and fetal health"],"prefix":"10.1111","volume":"94","author":[{"given":"Lene G.","family":"Rasmussen","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Oslo University Hospital Oslo Norway"},{"name":"Faculty of Medicine University of Copenhagen Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacob 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