{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T11:40:41Z","timestamp":1790077241015,"version":"4.0.1"},"reference-count":14,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,4,29]],"date-time":"2015-04-29T00:00:00Z","timestamp":1430265600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003744","name":"Stiftelsen Handlanden Hjalmar Svenssons","doi-asserted-by":"publisher","award":["EK-f1397\/10"],"award-info":[{"award-number":["EK-f1397\/10"]}],"id":[{"id":"10.13039\/501100003744","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Assar Gabrielsson\u00b4s Foundation for Cancer-Related Clinical Research","award":["EK-f-51\/12"],"award-info":[{"award-number":["EK-f-51\/12"]}]},{"name":"The Gothenburg Medical Society","award":["EK-f-984\/08"],"award-info":[{"award-number":["EK-f-984\/08"]}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2015,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate all cases of cervical cancer associated with pregnancy during 16\u00a0years in the Western Region of Sweden.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Retrospective, descriptive cohort study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting and population<\/jats:title><jats:p>All women with cervical cancer, diagnosed during pregnancy or within 6\u00a0months after parturition, between 1993 and 2008.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study was based on data from different registers and medical records.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measures<\/jats:title><jats:p>Incidence, diagnostic measures, treatment and outcome of disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Cervical cancer was diagnosed in 47 women (15.6\/100\u00a0000 deliveries). Sixteen women had abnormal vaginal bleeding and\/or discharge. The other women were asymptomatic and diagnosed by abnormal cervical smear or clinical signs at vaginal examination. Nine women had atypical squamous cells of uncertain significance as presenting by cervical atypia. Twenty\u2010two women had stage IA, 17 stage IB1, six stage IB2 and two stage IIA cancer. Cancer was diagnosed in the first trimester in two, in the second trimester in 14, in the third trimester in five and postpartum in 26 women. Histology revealed squamous cell carcinoma in 36 women, adenocarcinoma in eight, and adenosquamous carcinoma in three. Twenty women underwent cesarean section due to diagnosed or clinically suspected cancer, combined with the Wertheim\u2013Meigs radical hysterectomy in six women. Sixteen women with stage IA1 cancer without signs of vascular invasion underwent conization as definitive therapy. Six women died of the disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Early detection of cervical cytological atypia and proper follow\u2010up during pregnancy led to detection of a high proportion of stage I cancer cases, which could be cured with fertility\u2010sparing therapy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aogs.12645","type":"journal-article","created":{"date-parts":[[2015,4,3]],"date-time":"2015-04-03T18:54:11Z","timestamp":1428087251000},"page":"654-659","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Support for down\u2010staging of pregnancy\u2010associated cervical cancer"],"prefix":"10.1111","volume":"94","author":[{"given":"Cecilia","family":"K\u00e4rrberg","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Sahlgrenska Academy University of Gothenburg Gothenburg 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