{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T15:57:20Z","timestamp":1778169440130,"version":"3.51.4"},"reference-count":35,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2015,8,13]],"date-time":"2015-08-13T00:00:00Z","timestamp":1439424000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Carl von Linn\u00e9 Clinic, Uppsala"},{"name":"Department of Women's and Children's Health"},{"name":"Family Planning Fund in Uppsala, Uppsala University, Uppsala, Sweden"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2015,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>We compared the ability of four different ovarian reserve tests (<jats:styled-content style=\"fixed-case\">ORT<\/jats:styled-content>s) to predict live births per started in\u00a0vitro fertilization\u2013intracytoplasmic sperm injection (<jats:styled-content style=\"fixed-case\">IVF<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">ICSI<\/jats:styled-content>) cycle, and poor and excessive response to controlled ovarian hyperstimulation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>This was a cohort study in a private infertility center in collaboration with Uppsala University, comprising 1230 <jats:styled-content style=\"fixed-case\">IVF<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">ICSI<\/jats:styled-content> cycles in 892 consecutive women between April 2008 and June 2011. Anti\u2010M\u00fcllerian hormone (<jats:styled-content style=\"fixed-case\">AMH<\/jats:styled-content>) levels, antral follicle counts (<jats:styled-content style=\"fixed-case\">AFC<\/jats:styled-content>), combinations of basal levels of follicle\u2010stimulating hormone and luteinizing hormone, and menstrual cycle lengths were analyzed for correlation and treatment outcome prediction in age\u2010adjusted statistical models. Stepwise multivariable generalized estimating equation analyses were carried out in a sub\u2010group with complete data on all four <jats:styled-content style=\"fixed-case\">ORT<\/jats:styled-content>s (620 cycles in 443 women). Odds ratios and <jats:italic>c<\/jats:italic>\u2010statistics were calculated in the largest available set of data for each significant variable. Primary outcomes were live birth rate per started cycle and poor and excessive ovarian response to controlled ovarian hyper\u2010stimulation (defined by the ovarian sensitivity index).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All <jats:styled-content style=\"fixed-case\">ORT<\/jats:styled-content>s correlated significantly with each other, with the strongest correlation between <jats:styled-content style=\"fixed-case\">AFC<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">AMH<\/jats:styled-content> (<jats:italic>r<\/jats:italic>\u00a0=\u00a00.71, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.0001). Univariately, <jats:styled-content style=\"fixed-case\">AMH<\/jats:styled-content> and age equivalently predicted live birth (<jats:italic>c<\/jats:italic>\u2010statistic 0.61), and together they provided a significantly better model (<jats:italic>c<\/jats:italic>\u2010statistic 0.64). For prediction of poor and excessive response the best model included <jats:styled-content style=\"fixed-case\">AMH<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> AFC<\/jats:styled-content> and age (<jats:italic>c<\/jats:italic>\u2010statistic 0.89).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">AMH<\/jats:styled-content> improves the ability to estimate live birth rates after assisted reproduction compared with female age alone. <jats:styled-content style=\"fixed-case\">AMH<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> AFC<\/jats:styled-content> and age together constituted the best model for prediction of ovarian response.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aogs.12710","type":"journal-article","created":{"date-parts":[[2015,7,16]],"date-time":"2015-07-16T14:11:45Z","timestamp":1437055905000},"page":"1056-1063","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":41,"title":["Comparing four ovarian reserve markers \u2013 associations with ovarian response and live births after assisted reproduction"],"prefix":"10.1111","volume":"94","author":[{"given":"Thomas","family":"Brodin","sequence":"first","affiliation":[{"name":"Department of Women's and Children's Health Uppsala University Uppsala Sweden"},{"name":"Carl von Linn\u00e9 Clinic Uppsala Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nermin","family":"Hadziosmanovic","sequence":"additional","affiliation":[{"name":"Uppsala Clinical Research Center Uppsala 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