{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T08:40:52Z","timestamp":1775119252503,"version":"3.50.1"},"reference-count":29,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,11,30]],"date-time":"2015-11-30T00:00:00Z","timestamp":1448841600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100004441","name":"Styrelsen f\u00f6r Internationellt Utvecklingssamarbete","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004441","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004359","name":"Vetenskapsr\u00e5det","doi-asserted-by":"publisher","award":["2011\u20103525"],"award-info":[{"award-number":["2011\u20103525"]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Although home use of misoprostol for early medical abortion is considered to be safe, effective and feasible, it has not become standard service delivery practice. The aim of this study was to compare the efficacy, safety, and acceptability of home use of misoprostol with clinic misoprostol in a low\u2010resource setting.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>This was a secondary analysis of a randomized controlled trial conducted in six primary care clinics in India. Women seeking medical abortion within up to nine gestational weeks (<jats:italic>n<\/jats:italic> = 731) received mifepristone in the clinic and were allocated either to home or clinic administration of misoprostol. Follow\u2010up contact was after 10\u201315 days.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 731 participants, 73% were from rural areas and 55% had no formal education. Complete abortion rates in the home and clinic misoprostol groups were 94.2 and 94.4%, respectively. The rate of adverse events was similar in both groups (0.3%). A greater proportion of home users (90.2%) said that they would opt for misoprostol at home in the event of a future abortion compared with clinic users (79.7%) who would opt for misoprostol at the clinic in a similar situation (<jats:italic>p<\/jats:italic> = 0.0002). Ninety\u2010six percent women using misoprostol at home or in the clinic were satisfied with their abortion experience.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Home\u2010use of misoprostol for early medical abortion is as effective and acceptable as clinic use, in low resource settings. Women should be offered a choice of this option regardless of distance of their residence from the clinic and communication facilities.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aogs.12815","type":"journal-article","created":{"date-parts":[[2015,11,13]],"date-time":"2015-11-13T07:46:49Z","timestamp":1447400809000},"page":"173-181","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Home use of misoprostol for early medical abortion in a low resource setting: secondary analysis of a randomized controlled trial"],"prefix":"10.1111","volume":"95","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1674-9617","authenticated-orcid":false,"given":"Kirti","family":"Iyengar","sequence":"first","affiliation":[{"name":"Department of Women's and Children's Health Karolinska Institute WHO Collaborating Centre Karolinska University Hospital Stockholm Sweden"},{"name":"Action Research &amp; Training for Health (ARTH) Udaipur India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8947-2949","authenticated-orcid":false,"given":"Marie","family":"Klingberg\u2010Allvin","sequence":"additional","affiliation":[{"name":"Department of Women's and Children's Health Karolinska Institute WHO Collaborating Centre Karolinska University Hospital Stockholm Sweden"},{"name":"School of Education, Health and Social Studies Dalarna University Falun Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2874-002X","authenticated-orcid":false,"given":"Sharad D.","family":"Iyengar","sequence":"additional","affiliation":[{"name":"Action Research &amp; 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