{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T23:20:39Z","timestamp":1782516039983,"version":"3.54.5"},"reference-count":30,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2015,12,8]],"date-time":"2015-12-08T00:00:00Z","timestamp":1449532800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2016,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>A protocol including judicious use of oxytocin augmentation was investigated to determine whether it would change how oxytocin was used and eventually influence labor and fetal outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>The population of this cohort study comprised 20 227 delivering women with singleton pregnancies \u226537 weeks, cephalic presentation, spontaneous or induced onset of labor, without previous cesarean section. Women delivering from 2009 to 2013 at Stavanger University Hospital, Norway, were included. Data were collected prospectively. Before implementing the protocol in 2010, oxytocin augmentation was used if progression of labor was perceived as slow. After implementation, oxytocin could only be started when the cervical dilation had crossed the 4\u2010h action line in the partograph.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The overall use of oxytocin augmentation was significantly reduced from 34.9% to 23.1% (<jats:italic>p<\/jats:italic> &lt; 0.01). The overall frequency of emergency cesarean sections decreased from 6.9% to 5.3% (<jats:italic>p<\/jats:italic> &lt; 0.05) and the frequency of emergency cesarean sections performed due to fetal distress was reduced from 3.2% to 2.0% (<jats:italic>p<\/jats:italic> = 0.01). The rate of women with duration of labor over 12 h increased from 4.4% to 8.5% (<jats:italic>p<\/jats:italic> &lt; 0.01) and more women experienced severe estimated postpartum hemorrhage (2.6% vs. 3.7%; <jats:italic>p<\/jats:italic> = 0.01). The frequency of children with pH &lt;7.1 in the umbilical artery was reduced from 4.7% to 3.2% (<jats:italic>p<\/jats:italic> &lt; 0.01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The frequency of emergency cesarean section was reduced after implementing judicious use of oxytocin augmentation. Our findings may be of interest in the ongoing discussion of how the balanced use of oxytocin for labor augmentation can best be achieved.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aogs.12821","type":"journal-article","created":{"date-parts":[[2015,11,17]],"date-time":"2015-11-17T15:20:40Z","timestamp":1447773640000},"page":"355-361","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":35,"title":["Judicious use of oxytocin augmentation for the management of prolonged labor"],"prefix":"10.1111","volume":"95","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0983-4434","authenticated-orcid":false,"given":"Janne","family":"Rossen","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology S\u00f8rlandet Hospital HF Kristiansand Norway"},{"name":"Department of Laboratory Medicine Children's and Women's Health Norwegian University of Science and Technology Trondheim Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3600-0283","authenticated-orcid":false,"given":"Tilde B.","family":"\u00d8stborg","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Stavanger University Hospital Stavanger Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1368-9105","authenticated-orcid":false,"given":"Elsa","family":"Lindtj\u00f8rn","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Stavanger University Hospital Stavanger Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6240-4794","authenticated-orcid":false,"given":"J\u00f8rn","family":"Schulz","sequence":"additional","affiliation":[{"name":"Department of Clinical Science University of Stavanger Stavanger Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3162-9595","authenticated-orcid":false,"given":"Torbj\u00f8rn M.","family":"Eggeb\u00f8","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Stavanger University Hospital Stavanger Norway"},{"name":"National Center for Fetal Medicine St. Olavs Hospital \u2013 Trondheim University Hospital Trondheim Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,12,8]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2014.09.008"},{"key":"e_1_2_8_3_1","first-page":"CD009241","article-title":"Oxytocin augmentation of labour in women with epidural analgesia for reducing operative deliveries","volume":"7","author":"Costley PL","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2007.08.026"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.13281"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2008.01819.x"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2008.01962.x"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016340903358812"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e3181e5e2ec"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2007.01602.x"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1471-0528.2003.02298.x"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e31818da2c7"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.a1021"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpobgyn.2012.09.004"},{"key":"e_1_2_8_15_1","unstructured":"WHO recommendations for augmentation of labour.2014. 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