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This may be due to the contrasting uterotonic needs of the different underlying pathologies. In placenta adherens, oxytocics have been used to contract the retro\u2010placental myometrium. However, if injected locally through the umbilical vein, they bypass the myometrium and perfuse directly into the venous system. Intravenous injection is an alternative but exacerbates a trapped placenta. Conversely, for trapped placentas, a relaxant could help by resolving cervical constriction, but would worsen the situation for placenta adherens. This confusion over medical treatment will continue unless we can find a way to diagnose the underlying pathology. This will allow us to stop treating the retained placenta as a single entity and to deliver targeted treatments.<\/jats:p>","DOI":"10.1111\/aogs.12848","type":"journal-article","created":{"date-parts":[[2016,1,14]],"date-time":"2016-01-14T03:35:13Z","timestamp":1452742513000},"page":"501-504","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Retained placenta: will medical treatment ever be possible?"],"prefix":"10.1111","volume":"95","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4811-6101","authenticated-orcid":false,"given":"Achier D.","family":"Akol","sequence":"first","affiliation":[{"name":"Department of Women's and Children's Health University of Liverpool Liverpool UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1909-337X","authenticated-orcid":false,"given":"Andrew D.","family":"Weeks","sequence":"additional","affiliation":[{"name":"Department of Women's and Children's Health University of Liverpool Liverpool UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,2,4]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(14)70227-X"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.12869"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.3109\/01443615.2010.531301"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.12635"},{"key":"e_1_2_8_6_1","doi-asserted-by":"crossref","first-page":"99","DOI":"10.4103\/1115-2613.278309","article-title":"An appraisal of retained placenta at the university of port harcourt teaching hospital: a five\u2010year review","volume":"24","author":"John CO","year":"2015","journal-title":"Niger J Med"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)61752-9"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000151993.83276.70"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(11)90788-1"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.2000.00057.x"},{"key":"e_1_2_8_11_1","first-page":"CD001337","article-title":"Umbilical vein injection for management of retained placenta","volume":"5","author":"Nardin JM","year":"2011","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_8_12_1","volume-title":"National Institute for Health and Clinical Excellence, Intrapartum care: care of healthy women and their babies during childbirth. 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