{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T02:15:01Z","timestamp":1782353701549,"version":"3.54.5"},"reference-count":30,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2016,4,28]],"date-time":"2016-04-28T00:00:00Z","timestamp":1461801600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"University of Gothenburg\/Sahlgrenska University Hospital","award":["LUA\/ALF 70940"],"award-info":[{"award-number":["LUA\/ALF 70940"]}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2016,8]]},"abstract":"Abstract<\/jats:title>Introduction<\/jats:title>Previous studies have shown an increased risk of obstetric complications in pregnancies after oocyte donation (OD<\/jats:styled-content>). The present study includes all singletons born after OD<\/jats:styled-content> over 10 years in Sweden.<\/jats:p><\/jats:sec>Material and methods<\/jats:title>This was a retrospective population\u2010based cohort study. Data from all Swedish in vitro fertilization (IVF<\/jats:styled-content>) clinics between 2003 and 2012 were collected. Data were cross\u2010linked with the Swedish Medical Birth Registry. The study included 388 OD<\/jats:styled-content> singletons, 26 696 IVF<\/jats:styled-content>\/ICSI<\/jats:styled-content> singletons and 999 804 spontaneously conceived (SC<\/jats:styled-content>) singletons. An adjusted odds ratio (aOR<\/jats:styled-content>) was calculated with adjustment for relevant confounders.<\/jats:p><\/jats:sec>Results<\/jats:title>Singleton OD<\/jats:styled-content> pregnancies had a significantly increased risk of preeclampsia compared with IVF<\/jats:styled-content> (aOR<\/jats:styled-content> 3.05; 95% CI<\/jats:styled-content> 2.23\u20134.16) and SC<\/jats:styled-content> (aOR<\/jats:styled-content> 2.84; 95% CI<\/jats:styled-content> 2.10\u20133.84), and increased risk of postpartum hemorrhage (>1000 mL<\/jats:styled-content>) compared with IVF<\/jats:styled-content> (aOR<\/jats:styled-content> 2.66; 95% CI<\/jats:styled-content> 2.04\u20133.49) and SC<\/jats:styled-content> (aOR<\/jats:styled-content> 2.87; 95% CI<\/jats:styled-content> 2.20\u20133.71), a higher risk of preterm birth (<37 weeks) compared with IVF<\/jats:styled-content> (aOR<\/jats:styled-content> 1.79; 95% CI<\/jats:styled-content> 1.30\u20132.46) and SC<\/jats:styled-content> (aOR<\/jats:styled-content> 1.58; 95% CI<\/jats:styled-content> 1.15\u20132.16) and a higher risk of low birthweight (<2500 g) compared with IVF<\/jats:styled-content> (aOR<\/jats:styled-content> 1.67; 95% CI<\/jats:styled-content> 1.15\u20132.42) and SC<\/jats:styled-content> (aOR<\/jats:styled-content> 1.46; 95% CI<\/jats:styled-content> 1.01\u20132.11). The rate of large\u2010for\u2010gestational age was significantly increased in singletons born after OD<\/jats:styled-content> with frozen cycles than with fresh cycles (odds ratio 5.29, 95% CI 1.30\u201321.54).<\/jats:p><\/jats:sec>Conclusions<\/jats:title>Singleton pregnancies conceived after OD<\/jats:styled-content> are associated with increased maternal and perinatal risks compared with IVF<\/jats:styled-content>\/ICSI<\/jats:styled-content> pregnancies using the woman's own oocytes and with SC<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aogs.12904","type":"journal-article","created":{"date-parts":[[2016,4,10]],"date-time":"2016-04-10T14:12:12Z","timestamp":1460297532000},"page":"879-886","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":36,"title":["High risks of maternal and perinatal complications in singletons born after oocyte donation"],"prefix":"10.1111","volume":"95","author":[{"given":"Sarah","family":"Nejdet","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Institute of Clinical Science Sahlgrenska Academy Gothenburg University Reproductive Medicine Sahlgrenska University Hospital Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina","family":"Bergh","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Institute of Clinical Science Sahlgrenska Academy Gothenburg University Reproductive Medicine Sahlgrenska University Hospital Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5765-2630","authenticated-orcid":false,"given":"Karin","family":"K\u00e4ll\u00e9n","sequence":"additional","affiliation":[{"name":"Department of Reproduction Epidemiology Tornblad Institute Institution of Clinical Science Lund University Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2475-2226","authenticated-orcid":false,"given":"Ulla\u2010Britt","family":"Wennerholm","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Institute of Clinical Science Sahlgrenska Academy Gothenburg University East Hospital Sahlgrenska University Hospital Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann","family":"Thurin\u2010Kjellberg","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Institute of Clinical Science Sahlgrenska Academy Gothenburg University Reproductive Medicine Sahlgrenska University Hospital Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,4,28]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/307174a0"},{"key":"e_1_2_9_3_1","first-page":"181","article-title":"Oocyte donation treats infertility in survivors of malignancies: ten\u2010year experience","volume":"18","author":"Kavic SM","year":"2001","journal-title":"J Assist Reprod Genet"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/13.2.483"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deu175"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deu084"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dms044"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)61041-7"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2010.07.1075"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/17.10.2636"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2006.08.105"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2013.01.128"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7827-10-42"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2010.11.029"},{"key":"e_1_2_9_15_1","doi-asserted-by":"crossref","first-page":"1858","DOI":"10.1093\/humrep\/deg384","article-title":"Elective single embryo transfer yields good delivery rates in oocyte donation","volume":"18","author":"S\u00f6derstr\u00f6m\u2010Anttila V","year":"2003","journal-title":"Hum Reprod"},{"key":"e_1_2_9_16_1","unstructured":"National Board of Health and Welfare Centre for Epidemiology. 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