{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T13:12:29Z","timestamp":1791292349859,"version":"4.1.0"},"reference-count":25,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2016,5,30]],"date-time":"2016-05-30T00:00:00Z","timestamp":1464566400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The purpose of the present study was to evaluate learning curves and short\u2010term outcomes following laparoscopic surgery for early endometrial cancer in women of different body mass index (<jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content>) classes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>Data from 227 women planned for laparoscopic surgery for presumed stage I endometrial cancer were collected retrospectively from a Danish gynecologic oncology unit. Surgery included laparoscopic hysterectomy and bilateral salpingo\u2010oophorectomy with or without pelvic lymphadenectomy (<jats:styled-content style=\"fixed-case\">PLA<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Median length of operations was 60 min (range, 30\u2013197) and 120 min (range, 60\u2013230), depending on whether <jats:styled-content style=\"fixed-case\">PLA<\/jats:styled-content> was included. The median pelvic lymph node yield was 18 (range, 7\u201342). For staging with <jats:styled-content style=\"fixed-case\">PLA<\/jats:styled-content> there was a learning curve when measured as operative time as well as lymph node yield, and a level of proficiency was not reached after 40 operations. The women had a perioperative complication rate of 4.5% and a median hospital stay of one night. Postoperative complication rate was 12%, comprising vaginal cuff hematoma (3.1%), vaginal cuff rupture (0.9%), trocar hernia (1.3%), ureter lesion (0.4%), bowel lesion (0.4%), reoperation (0.9%) and other complications (4.5%). All peri\u2010 and postoperative outcomes were independent of <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> classes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our data suggest that laparoscopic surgery for early endometrial cancer is feasible and safe. With increasing surgeon's experience there is a significant decrease in operative time and increase in the number of lymph nodes harvested. In experienced hands, either operative time, complications or length of stay are not affected by increasing <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content>, even when women are morbidly obese.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aogs.12908","type":"journal-article","created":{"date-parts":[[2016,4,21]],"date-time":"2016-04-21T17:41:23Z","timestamp":1461260483000},"page":"894-900","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Laparoscopic surgery for early endometrial cancer"],"prefix":"10.1111","volume":"95","author":[{"given":"Gitte","family":"Bennich","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Zealand University Hospital Roskilde Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5115-1445","authenticated-orcid":false,"given":"Martin","family":"Rudnicki","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Odense University Hospital Odense Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pernille D.","family":"Lassen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Zealand University Hospital Roskilde Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,5,30]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.20107"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)60442-5"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/IGC.0000000000000008"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1006\/gyno.1993.1242"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2013.01.005"},{"key":"e_1_2_9_7_1","first-page":"CD006655","article-title":"Laparoscopy versus laparotomy for the management of early stage endometrial cancer","volume":"9","author":"Galaal K","year":"2012","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2008.09.014"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-014-3517-9"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-007-9440-6"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1006\/gyno.2001.6548"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2013.11.010"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1006\/gyno.2000.5914"},{"key":"e_1_2_9_14_1","first-page":"2497","article-title":"Advantages of laparoscopy versus laparotomy in extremely obese women (BMI >35) with early\u2010stage endometrial cancer: a multicenter study","volume":"34","author":"Tinelli R","year":"2014","journal-title":"Anticancer Res"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1438.2005.15223.x"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2008.06.030"},{"key":"e_1_2_9_17_1","first-page":"589","article-title":"Long\u2010term follow\u2010up after laparoscopic management of endometrial cancer in the obese: a fifteen\u2010year cohort study","volume":"18","author":"Rabischong B","year":"2011","journal-title":"J Minim Invasive Surg"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.22.3248"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2011.38.8645"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11912-012-0270-8"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/PPO.0b013e31828a3293"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2015.08.887"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.3109\/01443615.2013.812623"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2010.11.034"},{"key":"e_1_2_9_25_1","first-page":"45","article-title":"Laparoscopic staging of endometrial cancer. 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