{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T22:22:34Z","timestamp":1783030954570,"version":"3.54.6"},"reference-count":24,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2016,7,6]],"date-time":"2016-07-06T00:00:00Z","timestamp":1467763200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100006095","name":"Helse S\u00f8r-\u00d8st RHF","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006095","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2016,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Internal design flaws in previous reports of pregnancies following kidney transplantation have been outlined, and the need for a validation has been stated. The aim of this study was to collect information about obstetrical and neonatal outcomes in all Norwegian pregnancies following maternal kidney transplantation, and to compare these data with the general Norwegian population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>A retrospective cohort study based on 1 272 000 deliveries in Norway between 1969 and 2013. All data were collected from medical records. From the source population, we compared 119 first deliveries in kidney transplanted women with 238 first deliveries in nontransplanted women. An explanatory strategy was used in the analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The risk of preeclampsia was significantly increased in kidney\u2010transplanted women compared with nontransplanted women (adjusted incidence rate ratio: 6.06, 95% confidence interval 3.18\u201311.55). Additionally, preeclampsia in kidney\u2010transplanted women was early onset (diagnosed &lt;34 gestational weeks) in half of the cases. There were also persistent risks of cesarean delivery (adjusted incidence rate ratio 4.14, 95% confidence interval 2.56\u20136.66), preterm delivery (adjusted incidence rate ratio 4.45, 95% confidence interval 2.13\u20139.30) and a birthweight below the 10th centile (22.7% vs. 9.7%) in the kidney\u2010transplanted group. A high proportion (63%) of the kidney\u2010transplanted women with chronic hypertension developed preeclampsia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Using consistent diagnostic criteria, this study shows high rates of maternal and neonatal complications in pregnancies following kidney transplantation. In particular, we reveal a high rate of early\u2010onset preeclampsia requiring operative preterm delivery, conferring long\u2010term risks on both the mother and child.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aogs.12937","type":"journal-article","created":{"date-parts":[[2016,6,11]],"date-time":"2016-06-11T15:06:54Z","timestamp":1465657614000},"page":"1153-1161","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Pregnancy outcomes following maternal kidney transplantation: a national cohort study"],"prefix":"10.1111","volume":"95","author":[{"given":"Guri B.","family":"Majak","sequence":"first","affiliation":[{"name":"Department of Obstetrics, Women and Children\u2032s Division Oslo University Hospital Rikshospitalet Oslo Norway"},{"name":"Norwegian National Advisory Unit on Women\u2032s Health Oslo University Hospital, Rikshospitalet Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irene","family":"Sandven","sequence":"additional","affiliation":[{"name":"Oslo Centre for Biostatistics and Epidemiology Oslo University Hospital Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bj\u00f8rg","family":"Lorentzen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Women and Children\u2032s Division Oslo University Hospital Rikshospitalet Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siri","family":"Vangen","sequence":"additional","affiliation":[{"name":"Norwegian National Advisory Unit on Women\u2032s Health Oslo University Hospital, Rikshospitalet Oslo Norway"},{"name":"University of Oslo Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3195-5558","authenticated-orcid":false,"given":"Anna V.","family":"Reis\u00e6ter","sequence":"additional","affiliation":[{"name":"Department of Transplantation Medicine Oslo University Hospital, Rikshospitalet Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tore","family":"Henriksen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Women and Children\u2032s Division Oslo University Hospital Rikshospitalet Oslo Norway"},{"name":"University of Oslo Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trond M.","family":"Michelsen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Women and Children\u2032s Division Oslo University Hospital Rikshospitalet Oslo Norway"},{"name":"Norwegian National Advisory Unit on Women\u2032s Health Oslo University Hospital, Rikshospitalet Oslo Norway"},{"name":"Research Unit S\u00f8rlandet Hospital Arendal Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,7,6]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-6386(99)70296-9"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ackd.2007.01.003"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2011.03656.x"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2005.00607.x"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trre.2008.05.001"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.tp.0000263357.44975.d0"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0706790"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000437382.03963.88"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0412.2000.079006440.x"},{"key":"e_1_2_8_11_1","unstructured":"Norwegian National Health Institute.Norwegian Birth Registry. 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