{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T16:31:14Z","timestamp":1781195474213,"version":"3.54.1"},"reference-count":21,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2016,7,26]],"date-time":"2016-07-26T00:00:00Z","timestamp":1469491200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004348","name":"Stockholms L\u00e4ns Landsting","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004348","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2016,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The aim of this study was to investigate the correlation between increasing time since fetal heart rate (<jats:styled-content style=\"fixed-case\">FHR<\/jats:styled-content>) accelerations, positive (no acceleration) stimulation tests and fetal acidemia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>Observational study of <jats:styled-content style=\"fixed-case\">FHR<\/jats:styled-content> recordings from 1070 laboring women with indication for fetal scalp blood sampling (<jats:styled-content style=\"fixed-case\">FBS<\/jats:styled-content>). <jats:styled-content style=\"fixed-case\">FHR<\/jats:styled-content> traces were scrutinized regarding acceleration at <jats:styled-content style=\"fixed-case\">FBS<\/jats:styled-content> and duration since most recent acceleration. The appraiser was blinded to the <jats:styled-content style=\"fixed-case\">FBS<\/jats:styled-content> result.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>At the first sampling, 8.8% of fetuses had lactate concentration &gt;4.8 mmol\/L. There were no differences between those with recent accelerations (\u226460 min), and absent accelerations (&gt;60 min or never) prior to <jats:styled-content style=\"fixed-case\">FBS<\/jats:styled-content> (8.3% vs. 8.9%, <jats:italic>p<\/jats:italic> = 0.71). Corresponding analyses for subgroups were: fetuses with isolated absence of accelerations, 3.7% vs. 1.5% (<jats:italic>p<\/jats:italic> = 0.41), fetuses without decelerations (i.e. reduced variability and\/or tachycardia), 6.1% vs. 5.1% (<jats:italic>p<\/jats:italic> = 0.81) and fetuses with serious decelerations (i.e. late or complicated variable), 15.0% vs. 16.1% (<jats:italic>p<\/jats:italic> = 0.87). Among fetuses with serious decelerations, increasing duration from most recent acceleration had a weak but statistically significant correlation to increased lactate concentration (<jats:italic>r<\/jats:italic><jats:sub>s<\/jats:sub> = 0.12, <jats:italic>p<\/jats:italic> = 0.03). The positive likelihood ratio for acidemia with no response at <jats:styled-content style=\"fixed-case\">FBS<\/jats:styled-content> was 1.15.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In a population with <jats:styled-content style=\"fixed-case\">FBS<\/jats:styled-content> performed upon indication, there was no correlation between duration since last <jats:styled-content style=\"fixed-case\">FHR<\/jats:styled-content> acceleration and increased lactate concentration. The majority of fetuses are not acidemic even when the <jats:styled-content style=\"fixed-case\">FHR<\/jats:styled-content> trace is pathological and stimulation tests are only helpful when accelerations are provoked.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aogs.12939","type":"journal-article","created":{"date-parts":[[2016,6,15]],"date-time":"2016-06-15T15:20:11Z","timestamp":1466004011000},"page":"1097-1103","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Absence of accelerations during labor is of little value in interpreting fetal heart rate patterns"],"prefix":"10.1111","volume":"95","author":[{"given":"Malin","family":"Holzmann","sequence":"first","affiliation":[{"name":"Department of Women's and Children's Health Karolinska Institute Karolinska University Hospital Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stina","family":"Wretler","sequence":"additional","affiliation":[{"name":"Department of Women's and Children's Health Karolinska Institute Karolinska University Hospital Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lennart","family":"Nordstr\u00f6m","sequence":"additional","affiliation":[{"name":"Department of Women's and Children's Health Karolinska Institute Karolinska University Hospital Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,7,26]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2015.06.020"},{"key":"e_1_2_8_3_1","first-page":"830","article-title":"Intrapartum fetal stimulation tests: a meta\u2010analysis","volume":"100","author":"Skupski DW","year":"2002","journal-title":"Obstet Gynecol"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e3181aef106"},{"key":"e_1_2_8_5_1","volume-title":"Intrapartum care: Care of healthy women and their babies during childbirth","author":"National Institute for Clinical Excellence","year":"2007"},{"key":"e_1_2_8_6_1","volume-title":"Intrapartum fetal surveillance, clinical guidelines","author":"Royal Australian and New Zealand College of Obstetricians and Gynaecologists","year":"2006"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1701-2163(16)32615-9"},{"key":"e_1_2_8_8_1","unstructured":"Swedish Society of Obstetrics and Gynecology.Guidelines for CTG interpretation and intervention.Swedish Society of Obstetrics and Gynecology 2009. Available online at:https:\/\/www.sfog.se\/media\/17094\/ctg_kort__slutversion.pdf.https:\/\/www.sfog.se\/start\/rad-riktlinjer\/sfog-rad-obstetrik\/forlossning\/(accessed 21 December 2009)."},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1272\/jnms.79.60"},{"key":"e_1_2_8_10_1","first-page":"159","article-title":"Guidelines for the use of fetal monitoring","volume":"25","author":"International Federation of Gynaecology & Obstetrics","year":"1987","journal-title":"Int J Gynaecol Obstet"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1515\/jpm-2014-0105"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.39553.406991.25"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1998.tb09346.x"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(99)70083-9"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2001.00034.x"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1515\/JPM.2006.057"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2008.02092.x"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199603073341001"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(83)90828-1"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(84)90199-6"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(84)90196-0"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2010.12.044"}],"container-title":["Acta Obstetricia et Gynecologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Faogs.12939","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aogs.12939","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T09:07:17Z","timestamp":1695546437000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/aogs.12939"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7,26]]},"references-count":21,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2016,10]]}},"alternative-id":["10.1111\/aogs.12939"],"URL":"https:\/\/doi.org\/10.1111\/aogs.12939","archive":["Portico"],"relation":{},"ISSN":["0001-6349","1600-0412"],"issn-type":[{"value":"0001-6349","type":"print"},{"value":"1600-0412","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,7,26]]},"assertion":[{"value":"2016-03-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-06-13","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-07-26","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}