{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T07:51:06Z","timestamp":1768290666268,"version":"3.49.0"},"reference-count":30,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2016,11,3]],"date-time":"2016-11-03T00:00:00Z","timestamp":1478131200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Our aim was to establish unconditional and conditional longitudinal reference ranges for cervical length throughout pregnancy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>Prospective longitudinal study. In singleton pregnancies repeated cervical length measurements were carried out by transvaginal ultrasound throughout gestation. Multilevel modeling was applied to establish cervical length reference ranges from 11 to 40 weeks.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In all, 4397 women contributed to 13 765 cervical length measurements. A linear mixed effects random intercept\u2013random slope model was fitted to the data. Mean cervical length had a negative non\u2010linear polynomial association with gestational age. Unconditional ranges were developed. Terms that allow the construction of personalized cervical length charts conditional to a previous measurement were calculated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>We constructed longitudinal reference charts for cervical length in singleton pregnancies. Cervical length should be adjusted according to specific gestational\u2010age\u2010dependent ranges. Individualization of cervical assessment is feasible by the application of charts conditional to previous measurements.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aogs.13025","type":"journal-article","created":{"date-parts":[[2016,9,17]],"date-time":"2016-09-17T01:26:51Z","timestamp":1474075611000},"page":"1376-1382","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Cervical length at 11\u201340 weeks: unconditional and conditional longitudinal reference ranges"],"prefix":"10.1111","volume":"95","author":[{"given":"Ioannis","family":"Papastefanou","sequence":"first","affiliation":[{"name":"Fetal Medicine Unit Leto Maternity Hospital Athens Greece"},{"name":"Emvryomitriki Fetal Medicine Unit Athens Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Athanasios","family":"Pilalis","sequence":"additional","affiliation":[{"name":"Fetal Medicine Unit Leto Maternity Hospital Athens 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