{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T10:34:25Z","timestamp":1769164465186,"version":"3.49.0"},"reference-count":32,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,1,10]],"date-time":"2017-01-10T00:00:00Z","timestamp":1484006400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100008392","name":"Sundhed og Sygdom, Det Frie Forskningsr\u00e5d","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008392","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003123","name":"Fetal Medicine Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003123","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002918","name":"Gentofte Hospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002918","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003035","name":"Aase og Ejnar Danielsens Fond","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003035","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001825","name":"Styrelsen for Forskning og Innovation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001825","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2017,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The objective was to investigate the association between chorionicity\u2010specific intertwin birthweight discordance and adverse outcomes including long\u2010term follow up at 6, 18, and 48\u201360 months after term via Ages and Stages Questionnaire.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>In this secondary analysis of a cohort study (Oldenburg et al., <jats:italic>n<\/jats:italic> = 1688) and a randomized controlled trial (PREDICT study, <jats:italic>n<\/jats:italic> = 1045) twin pairs were divided into three groups according to chorionicity\u2010specific birthweight discordance: &lt;75th percentile, 75th\u201390th percentile and &gt;90th percentile. Information on infant mortality, admittance to neonatal intensive care units, and gestational age at delivery was available for all pairs. Detailed neonatal outcomes were available for 656 pairs from PREDICT, of which 567 pairs had at least one Ages and Stages Questionnair follow\u2010up. Logistic regression models were used for dichotomous outcomes. Ages and Stages Questionnair scores were compared using the method of generalized estimating equation to account for the correlation within twins.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The 75th and 90th percentiles for birthweight discordance were 14.8 and 21.4% for monochorionic and 16.0 and 23.8% for dichorionic twins. After adjustment for small for gestational age and gender, birthweight discordance &gt;75th and &gt;90th percentile was associated with induced delivery &lt;34 weeks [odds ratio 1.71 (95% confidence interval 1.11\u20132.65) and odds ratio 2.83 (95% confidence interval 1.73\u20134.64), respectively]. Discordance &gt;75th\u2010percentile was associated with an increased risk of infant mortality after 28 days [odds ratio 4.69 (95% confidence interval 1.07\u201320.45)] but not with major neonatal complications or with low mean Ages and Stages Questionnair scores at 6, 18, and 48\u201360 months after term.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Chorionicity\u2010specific intertwin birthweight discordance is a risk factor for induced preterm delivery and infant mortality, but not for lower scores for neurophysiological development at 6, 18, and 48\u201360 months.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aogs.13062","type":"journal-article","created":{"date-parts":[[2016,11,18]],"date-time":"2016-11-18T17:46:50Z","timestamp":1479491210000},"page":"233-242","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Short\u2010 and long\u2010term perinatal outcome in twin pregnancies affected by weight discordance"],"prefix":"10.1111","volume":"96","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7475-513X","authenticated-orcid":false,"given":"Cathrine","family":"Vedel","sequence":"first","affiliation":[{"name":"Center of Fetal Medicine and Pregnancy Department of Obstetrics Rigshospitalet University Hospital Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Oldenburg","sequence":"additional","affiliation":[{"name":"Center of Fetal Medicine and Pregnancy Department of Obstetrics Rigshospitalet University Hospital Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katharina","family":"Worda","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Medical University of Vienna Vienna Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helle","family":"Larsen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Aalborg Hospital Aalborg Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anni","family":"Holmskov","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Viborg Hospital Viborg Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kirsten R.","family":"Andreasen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Hvidovre Hospital Hvidovre Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Niels","family":"Uldbjerg","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Aarhus University Hospital Skejby Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"Ramb","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology S\u00f8nderborg Hospital S\u00f8nderborg Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Birgit","family":"B\u00f8dker","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Nordsj\u00e6llands Hospital Hiller\u00f8d Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lillian","family":"Skibsted","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology University Hospital Roskilde Roskilde Denmark"},{"name":"Faculty of Health Sciences University of Copenhagen Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lene","family":"Sperling","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences University of Copenhagen Copenhagen Denmark"},{"name":"Department of Obstetrics and Gynecology Herlev Hospital Herlev Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan","family":"Hinterberger","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Klagenfurt General Hospital Klagenfurt Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5433-4776","authenticated-orcid":false,"given":"Lone","family":"Krebs","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Holb\u00e6k Hospital Holb\u00e6k Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helle","family":"Zingenberg","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Glostrup Hospital Glostrup Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eva\u2010Christine","family":"Weiss","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Medical University of Graz Graz Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isolde","family":"Strobl","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Medical University of Innsbruck Innsbruck Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lone","family":"Laursen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Odense University Hospital Odense Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeanette T.","family":"Christensen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Gentofte Hospital Gentofte Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vibeke","family":"Ersbak","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Silkeborg Hospital Silkeborg Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Inger","family":"Stornes","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Randers Hospital Randers Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisabeth","family":"Krampl\u2010Bettelheim","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Medical University of Vienna Vienna Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ann","family":"Tabor","sequence":"additional","affiliation":[{"name":"Center of Fetal Medicine and Pregnancy Department of Obstetrics Rigshospitalet University Hospital Copenhagen Denmark"},{"name":"Faculty of Health Sciences University of Copenhagen Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Line","family":"Rode","sequence":"additional","affiliation":[{"name":"Center of Fetal Medicine and Pregnancy Department of Obstetrics Rigshospitalet University Hospital Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,1,10]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1301467"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2011.06.075"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006250-199912000-00019"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.288.6.728"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000104060.37475.29"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(02)03119-8"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e31821fd208"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(02)01951-8"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2002.126961"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2003.210"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2015.02.024"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.semperi.2012.02.002"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.10057"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.9093"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1996.tb14164.x"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2013.08.016"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2003.07.004"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2012.04.001"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.11112"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2009-0829"},{"key":"e_1_2_8_22_1","first-page":"391","article-title":"Twin birth weight discordance: associated factors and outcome","volume":"20","author":"Mazher SB","year":"2010","journal-title":"J Coll Physicians Surg Pak"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2013.01.044"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2011.06.077"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2012.06.022"},{"key":"e_1_2_8_26_1","first-page":"795","article-title":"Growth retardation and discordant twin pregnancy. An immunomorphological and biochemical characterisation of the human umbilical cord","volume":"46","author":"Salvolini E","year":"1998","journal-title":"Biochem Mol Biol Int"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0033503"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0001566000001768"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.taap.2014.02.015"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.113.01494"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-200211000-00011"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(00)01111-X"},{"key":"e_1_2_8_33_1","first-page":"CD008549","article-title":"Customised versus population\u2010based growth charts as a screening tool for detecting small for gestational age infants in low\u2010risk pregnant women","volume":"5","author":"Carberry AE","year":"2014","journal-title":"Cochrane Database Syst Rev"}],"container-title":["Acta Obstetricia et Gynecologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Faogs.13062","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aogs.13062","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T19:23:52Z","timestamp":1695497032000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/aogs.13062"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1,10]]},"references-count":32,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2017,2]]}},"alternative-id":["10.1111\/aogs.13062"],"URL":"https:\/\/doi.org\/10.1111\/aogs.13062","archive":["Portico"],"relation":{},"ISSN":["0001-6349","1600-0412"],"issn-type":[{"value":"0001-6349","type":"print"},{"value":"1600-0412","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,1,10]]},"assertion":[{"value":"2016-07-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-11-10","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-01-10","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}