{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T03:51:50Z","timestamp":1785556310104,"version":"3.56.0"},"reference-count":20,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,2,3]],"date-time":"2017-02-03T00:00:00Z","timestamp":1486080000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2017,3]]},"abstract":"Abstract<\/jats:title>Introduction<\/jats:title>Point\u2010of\u2010care testing of fetal scalp blood lactate is used as an alternative to pH<\/jats:styled-content> analysis in fetal scalp blood sampling (FBS<\/jats:styled-content>) during labor. Lactate measurements are not standardized and values vary with each device used. The aim of this study was to evaluate StatStrip\u00ae<\/jats:sup> Lactate (SSL<\/jats:styled-content>) in the clinical setting in comparison with lactate (RLL<\/jats:styled-content>) and pH<\/jats:styled-content> (RL<\/jats:styled-content>pH) using RapidLab\u00ae<\/jats:sup>.<\/jats:p><\/jats:sec>Material and methods<\/jats:title>We obtained 323 FBS<\/jats:styled-content> samples from 139 women. Parallel sampling of SSL<\/jats:styled-content> and RLL<\/jats:styled-content>\/RL<\/jats:styled-content>pH was performed in 247 samples. Outcome measures were the agreement and discrepancy rates between SSL<\/jats:styled-content>, RLL<\/jats:styled-content> and RL<\/jats:styled-content>pH and the failure rate of all three methods. We constructed a Bland\u2013Altman graph to assess the variability between the measurements across the range of values. The discrepancy rates between methods were compared using previously established cut\u2010off values for SSL<\/jats:styled-content> indicating reassurance (<5.7 mmol\/L) and immediate delivery (>7.0 mmol\/L) with those for RL<\/jats:styled-content>pH (<7.20 and >7.25).<\/jats:p><\/jats:sec>Results<\/jats:title>SSL<\/jats:styled-content> showed excellent agreement with RLL<\/jats:styled-content> (R<\/jats:italic>2<\/jats:sup> = 0.742) and poor agreement with RL<\/jats:styled-content>pH (R<\/jats:italic>2<\/jats:sup> = 0.204). Failure rates for SSL<\/jats:styled-content>, RLL<\/jats:styled-content> and RL<\/jats:styled-content>pH were 7, 43 and 23%, respectively. Using the cut\u2010off values for reassurance and immediate delivery, the discrepancy rates between SSL<\/jats:styled-content> and RL<\/jats:styled-content>pH were 14 and 5%, respectively.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>SSL<\/jats:styled-content> is a reliable test to measure lactate in FBS<\/jats:styled-content> with a low failure rate. As there are discrepancies between SSL<\/jats:styled-content> and RL<\/jats:styled-content>pH, and the cut\u2010off values have not yet been evaluated prospectively regarding intervention rates and neonatal outcome, we recommend using SSL<\/jats:styled-content> in addition to pH<\/jats:styled-content> in FBS<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aogs.13078","type":"journal-article","created":{"date-parts":[[2016,12,9]],"date-time":"2016-12-09T19:46:41Z","timestamp":1481312801000},"page":"334-341","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Clinical evaluation of Statstrip\u00ae<\/sup> Lactate for use in fetal scalp blood sampling"],"prefix":"10.1111","volume":"96","author":[{"given":"Ayesha","family":"Heinis","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Radboud University Medical Center Nijmegen the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeroen","family":"van Dillen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Radboud University Medical Center Nijmegen the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janine","family":"Oosting","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine Radboud University Medical Center Nijmegen the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Rh\u00f6se","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Radboud University Medical Center Nijmegen the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Vandenbussche","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Radboud University Medical Center Nijmegen the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joris","family":"Van Drongelen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Radboud University Medical Center Nijmegen the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,2,3]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2006.00859.x"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1998.tb09346.x"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(97)70080-2"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(94)70101-6"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(99)70083-9"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1995.tb10878.x"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.39553.406991.25"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1479-828X.2004.00306.x"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpobgyn.2004.02.006"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1515\/cclm.2011.734"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2010.03.011"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0412.2011.01237.x"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(67)90515-7"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0412.2011.01228.x"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(86)90080-3"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1006\/exnr.1997.6482"},{"key":"e_1_2_9_18_1","first-page":"145","article-title":"Measurement of transcutaneous pCO2 and pO2 in the fetus during labor","volume":"236","author":"Schmidt S","year":"1985","journal-title":"Arch Gynecol Obstet"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0950-3552(96)80035-6"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1515\/cclm-2013-0732"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiochem.2008.08.088"}],"container-title":["Acta Obstetricia et Gynecologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Faogs.13078","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aogs.13078","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T19:16:08Z","timestamp":1695496568000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/aogs.13078"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2,3]]},"references-count":20,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2017,3]]}},"alternative-id":["10.1111\/aogs.13078"],"URL":"https:\/\/doi.org\/10.1111\/aogs.13078","archive":["Portico"],"relation":{},"ISSN":["0001-6349","1600-0412"],"issn-type":[{"value":"0001-6349","type":"print"},{"value":"1600-0412","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,2,3]]},"assertion":[{"value":"2016-04-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-11-30","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-02-03","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}