{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:44:17Z","timestamp":1787013857901,"version":"build-2736575974"},"reference-count":16,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2017,4,3]],"date-time":"2017-04-03T00:00:00Z","timestamp":1491177600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>\n                      In 2011 Danish national guidelines were changed towards a more aggressive induction and fetal surveillance policy from (1) induction of labor at gestational age (\n                      <jats:styled-content style=\"fixed-case\">GA<\/jats:styled-content>\n                      ) of 42\n                      <jats:sup>+0<\/jats:sup>\n                      \u00a0weeks and (2) no fetal surveillance after 40\n                      <jats:sup>+0<\/jats:sup>\n                      \u00a0weeks to (1) induction of labor between 41\n                      <jats:sup>+2<\/jats:sup>\n                      and 41\n                      <jats:sup>+6<\/jats:sup>\n                      \u00a0weeks, (2) earlier induction at 41\n                      <jats:sup>+0<\/jats:sup>\n                      \u00a0weeks in the case of maternal age &gt;40\u00a0years or body mass\u00a0index (\n                      <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content>\n                      ) &gt;35\u00a0kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      and (3) fetal surveillance at\n                      <jats:styled-content style=\"fixed-case\">GA<\/jats:styled-content>\n                      41\n                      <jats:sup>+0<\/jats:sup>\n                      \u00a0weeks.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and methods<\/jats:title>\n                    <jats:p>\n                      This national cohort study included all pregnancies that reached 41\n                      <jats:sup>+0<\/jats:sup>\n                      \u00a0weeks of gestation in 2008\u20132014 (\n                      <jats:italic>n\u00a0<\/jats:italic>\n                      =\u00a0102\u00a0167). Multivariate logistic regression analyses were used to estimate risks in the years after (2012\u20132014) vs. before (2008\u20132010) new national guidelines, adjusted for maternal age,\n                      <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content>\n                      , and parity.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      We observed a decline in stillbirths from 0.9\u2030 to 0.5\u2030 [odds ratio (\n                      <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\n                      )\n                      <jats:sub>adjusted<\/jats:sub>\n                      0.50, 95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      0.29\u20130.89,\n                      <jats:italic>p\u00a0<\/jats:italic>\n                      =\u00a00.018]. Furthermore, a decline in perinatal deaths from 1.3\u2030 to 0.8\u2030 (\n                      <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\n                      <jats:sub>adjusted<\/jats:sub>\n                      0.62, 95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      0.39\u20130.96,\n                      <jats:italic>p\u00a0<\/jats:italic>\n                      =\u00a00.033) and vacuum extraction (\n                      <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\n                      <jats:sub>adjusted<\/jats:sub>\n                      0.86, 95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      0.82\u20130.90,\n                      <jats:italic>p\u00a0<\/jats:italic>\n                      =\u00a00.007) was observed. The risk of cesarean section (\n                      <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\n                      <jats:sub>adjusted<\/jats:sub>\n                      0.98, 95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      0.94\u20131.02,\n                      <jats:italic>p\u00a0<\/jats:italic>\n                      =\u00a00.251), Apgar score below 7 at five minutes (\n                      <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\n                      <jats:sub>adjusted<\/jats:sub>\n                      0.96, 95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      0.81\u20131.14,\n                      <jats:italic>p\u00a0<\/jats:italic>\n                      =\u00a00.0.678) and admissions to the neonatal department (\n                      <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\n                      <jats:sub>adjusted<\/jats:sub>\n                      1.04, 95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      1.00\u20131.14,\n                      <jats:italic>p\u00a0<\/jats:italic>\n                      =\u00a00.064) did not change, whereas induction of labor increased from 28.2 to 42.6% (\n                      <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\n                      <jats:sub>adjusted<\/jats:sub>\n                      1.89, 95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      1.84\u20131.95,\n                      <jats:italic>p\u00a0<\/jats:italic>\n                      &lt;\u00a00.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study showed a decline in stillbirths and perinatal mortality after implementation of new Danish guidelines for post\u2010date pregnancies. The risk of interventions as cesarean section and vacuum extraction remained stable despite an increase in labor inductions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/aogs.13113","type":"journal-article","created":{"date-parts":[[2017,2,10]],"date-time":"2017-02-10T11:56:42Z","timestamp":1486727802000},"page":"862-867","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Decline in stillbirths and perinatal mortality after implementation of a more aggressive induction policy in post\u2010date pregnancies: a nationwide register study"],"prefix":"10.1111","volume":"96","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0342-0708","authenticated-orcid":false,"given":"Anne R.","family":"Zizzo","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Aarhus University Hospital Skejby 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