{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T12:13:10Z","timestamp":1792498390262,"version":"4.5.0"},"reference-count":18,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2017,7,12]],"date-time":"2017-07-12T00:00:00Z","timestamp":1499817600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100006342","name":"Association Vaincre la Mucoviscidose","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006342","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2017,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>With increasing life expectancy, more women with cystic fibrosis and diabetes mellitus become pregnant. We investigated how pre\u2010gestational diabetes (cystic fibrosis\u2010related diabetes) influenced pregnancy outcome and the clinical status of these women.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>We analyzed all pregnancies reported to the French cystic fibrosis registry between 2001 and 2012, and compared forced expiratory volume (<jats:styled-content style=\"fixed-case\">FEV<\/jats:styled-content><jats:sub>1<\/jats:sub>) and body mass index before and after pregnancy in women with and without pre\u2010gestational diabetes having a first delivery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total 249 women delivered 314 infants. Among these, 189 women had a first delivery and 29 of these had pre\u2010gestational diabetes. There was a trend towards a higher rate of assisted conception among diabetic women (53.8%) than non\u2010diabetic women (34.5%, <jats:italic>p<\/jats:italic> = 0.06), and the rate of cesarean section was significantly higher in diabetic women (48% vs. 21.4%, <jats:italic>p<\/jats:italic> = 0.005). The rate of preterm birth and mean infant birthweight did not differ significantly between diabetic and non\u2010diabetic women. Forced expiratory volume before pregnancy was significantly lower in the diabetic group. The decline in forced expiratory volume and body mass index following pregnancy did not differ between the women with and those without pre\u2010gestational diabetes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Pre\u2010gestational diabetes in women with cystic fibrosis is associated with a higher rate of cesarean section but does not seem to have a clinically significant impact on fetal growth or preterm delivery. The changes in maternal pulmonary and nutritional status following pregnancy in women with cystic fibrosis were not influenced by pre\u2010gestational diabetes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aogs.13185","type":"journal-article","created":{"date-parts":[[2017,6,24]],"date-time":"2017-06-24T14:44:36Z","timestamp":1498315476000},"page":"1223-1227","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Pregnancy outcome in women with cystic fibrosis\u2010related diabetes"],"prefix":"10.1111","volume":"96","author":[{"given":"Quitterie","family":"Reynaud","sequence":"first","affiliation":[{"name":"Cystic Fibrosis Adult Referral Care Center Department of Internal Medicine Civil Hospices of Lyon EA\u2010HESPER7425 University of Lyon Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"St\u00e9phanie","family":"Poupon\u2010Bourdy","sequence":"additional","affiliation":[{"name":"IMER Department 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