{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T03:33:22Z","timestamp":1769052802579,"version":"3.49.0"},"reference-count":39,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,12,12]],"date-time":"2017-12-12T00:00:00Z","timestamp":1513036800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The aim of this study was to evaluate if women meeting criteria for gestational diabetes mellitus (<jats:styled-content style=\"fixed-case\">GDM<\/jats:styled-content>) by the One Step test as per International Association of the Diabetes and Pregnancy Study Groups (<jats:styled-content style=\"fixed-case\">IADPSG<\/jats:styled-content>) criteria but not by other less strict criteria have adverse pregnancy outcomes compared with <jats:styled-content style=\"fixed-case\">GDM<\/jats:styled-content>\u2010negative controls. The primary outcome was the incidence of macrosomia, defined as birthweight &gt;\u00a04000\u00a0g.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>Electronic databases were searched from their inception until May 2017. All studies identifying pregnant women negative at the Two Step test, but positive at the One Step test for <jats:styled-content style=\"fixed-case\">IADPSG<\/jats:styled-content> criteria were included. We excluded studies that randomized women to the One Step vs. the Two Step tests; studies that compared different criteria within the same screening method; randomized studies comparing treatments for <jats:styled-content style=\"fixed-case\">GDM<\/jats:styled-content>; and studies comparing incidence of <jats:styled-content style=\"fixed-case\">GDM<\/jats:styled-content> in women doing the One Step test vs. the Two Step test.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Eight retrospective cohort studies, including 29\u00a0983 women, were included. Five study groups and four control groups were identified. The heterogeneity between the studies was high. Gestational hypertension, preeclampsia and large for gestational age, as well as in some analyses cesarean delivery, macrosomia and preterm birth, were significantly more frequent, and small for gestational age in some analyses significantly less frequent, in women <jats:styled-content style=\"fixed-case\">GDM<\/jats:styled-content>\u2010positive by the One Step, but not the Two Step.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Women meeting criteria for <jats:styled-content style=\"fixed-case\">GDM<\/jats:styled-content> by <jats:styled-content style=\"fixed-case\">IADPSG<\/jats:styled-content> criteria but not by other less strict criteria have an increased risk of adverse pregnancy outcomes such as gestational hypertension, preeclampsia and large for gestational age, compared with <jats:styled-content style=\"fixed-case\">GDM<\/jats:styled-content>\u2010negative controls. Based on these findings, and evidence from other studies that treatment decreases these adverse outcomes, we suggest screening for <jats:styled-content style=\"fixed-case\">GDM<\/jats:styled-content> using the One Step <jats:styled-content style=\"fixed-case\">IADPSG<\/jats:styled-content> criteria.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aogs.13254","type":"journal-article","created":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T13:47:11Z","timestamp":1509544031000},"page":"122-134","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Are women positive for the One Step but negative for the Two Step screening tests for gestational diabetes at higher risk for adverse outcomes?"],"prefix":"10.1111","volume":"97","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6535-4497","authenticated-orcid":false,"given":"Claudia","family":"Caissutti","sequence":"first","affiliation":[{"name":"Department of Experimental Clinical and Medical Science DISM, Clinic of Obstetrics and Gynecology University of Udine Udine Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adeeb","family":"Khalifeh","sequence":"additional","affiliation":[{"name":"Division of Maternal\u2013Fetal Medicine Department of Obstetrics and Gynecology Sidney Kimmel Medical College of Thomas Jefferson University Philadelphia PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0078-2113","authenticated-orcid":false,"given":"Gabriele","family":"Saccone","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Reproductive Sciences and Dentistry School of Medicine University of Naples Federico II Naples Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7420-1807","authenticated-orcid":false,"given":"Vincenzo","family":"Berghella","sequence":"additional","affiliation":[{"name":"Division of Maternal\u2013Fetal Medicine Department of Obstetrics and Gynecology Sidney Kimmel Medical College of Thomas Jefferson University Philadelphia PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,12,12]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"1","article-title":"Classification and diagnosis of diabetes","volume":"40","author":"American Diabetes Association","year":"2017","journal-title":"Diabetes Care"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc09-1848"},{"key":"e_1_2_8_4_1","unstructured":"WHO2013.Diagnostic Criteria and Classification of Hyperglycaemia First Detected in Pregnancy. 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