{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T07:53:13Z","timestamp":1740124393751,"version":"3.37.3"},"reference-count":29,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,12,12]],"date-time":"2017-12-12T00:00:00Z","timestamp":1513036800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>In this study, we examined changes in depot medroxyprogesterone acetate (<jats:styled-content style=\"fixed-case\">DMPA<\/jats:styled-content>) prescriptions over a time\u2010period when new professions started prescribing, and when the method gained some negative media attention.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>The Norwegian Prescription Database provided data on hormonal contraception from 2006 through 2012. We estimated the annual number of <jats:styled-content style=\"fixed-case\">DMPA<\/jats:styled-content> users by calculating doses sold per day\/1000 women and calculated, for each contraceptive method on annual basis, a proportion of defined daily doses of all hormonal contraceptives in five\u2010year age groups at reproductive age. All analyses were done in <jats:styled-content style=\"fixed-case\">SPSS<\/jats:styled-content>, version 22, with Chi\u2010square test, <jats:italic>t<\/jats:italic>\u2010test, and survival analysis with <jats:italic>p\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.05 as significance level.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were minor differences in overall <jats:styled-content style=\"fixed-case\">DMPA<\/jats:styled-content> use during the study years. The take\u2010out rate was equivalent to 11\u201312\/1000 women aged 15\u201349\u00a0years. <jats:styled-content style=\"fixed-case\">DMPA<\/jats:styled-content> sales amounted to nearly 4% of all daily doses of hormonal contraceptives sold. General practitioners and physicians without a specialty were the major prescribers. The number of starters decreased by nearly 40% during the study years and was consistent across age groups. The average use duration among starters was 17.7 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 17.5\u201317.9) months (range 0\u201390). There were minor changes in the relative proportion of long\u2010term users beyond 24\u00a0months during the study years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">DMPA<\/jats:styled-content> plays a minor role in the overall use of hormonal contraception in Norway, even among teenagers. The number of starters is decreasing, indicating a more restrictive attitude toward first use, especially among general practitioners.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aogs.13262","type":"journal-article","created":{"date-parts":[[2017,11,20]],"date-time":"2017-11-20T17:06:43Z","timestamp":1511197603000},"page":"151-157","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Decreasing trends in number of depot medroxyprogesterone acetate starters in Norway \u2013 a cross\u2010sectional study"],"prefix":"10.1111","volume":"97","author":[{"given":"Ingvild","family":"Roksvaag","sequence":"first","affiliation":[{"name":"Research Group Epidemiology of Chronic Diseases Department of Community Medicine Faculty of Health Sciences UiT The Arctic University of Norway Troms\u00f8 Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9875-4991","authenticated-orcid":false,"given":"Finn E.","family":"Skjeldestad","sequence":"additional","affiliation":[{"name":"Research Group Epidemiology of Chronic Diseases Department of Community Medicine Faculty of Health Sciences UiT The Arctic University of Norway Troms\u00f8 Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,12,12]]},"reference":[{"key":"e_1_2_9_2_1","first-page":"2803","article-title":"Prevensjonsbruken i Norge i 2005. 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