{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T01:39:09Z","timestamp":1793497149440,"version":"4.5.0"},"reference-count":20,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2018,7,16]],"date-time":"2018-07-16T00:00:00Z","timestamp":1531699200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100009633","name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["U01HD087213"],"award-info":[{"award-number":["U01HD087213"]}],"id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>\n                      The INTERGROWTH\u201021st project (\n                      <jats:styled-content style=\"fixed-case\">IG<\/jats:styled-content>\n                      \u201021) was recently performed aiming to provide a universal benchmark for comparing fetal growth across different ethnicities. Our aim was to compare the\n                      <jats:styled-content style=\"fixed-case\">IG<\/jats:styled-content>\n                      \u201021 with a customized standard for predicting pregnancies at risk for neonatal small\u2010for\u2010gestational age (\n                      <jats:styled-content style=\"fixed-case\">SGA<\/jats:styled-content>\n                      ) and adverse outcomes.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and methods<\/jats:title>\n                    <jats:p>\n                      This was a prospective cohort study including singleton pregnancies presenting for fetal growth assessment between 26 and 36\u00a0weeks of gestation. Fetal growth restriction was defined as estimated fetal weight &lt;10th centile for gestational age using\n                      <jats:styled-content style=\"fixed-case\">IG<\/jats:styled-content>\n                      \u201021 and a customized standard. Neonatal\n                      <jats:styled-content style=\"fixed-case\">SGA<\/jats:styled-content>\n                      was defined as birthweight &lt;10th centile for gestational age by the Alexander chart. Primary outcome was the prediction of neonatal\n                      <jats:styled-content style=\"fixed-case\">SGA<\/jats:styled-content>\n                      . Secondary outcomes included a composite of adverse neonatal outcomes. The discriminatory ability of each growth standard was compared using area under receiver operating characteristic curves (\n                      <jats:styled-content style=\"fixed-case\">AUC<\/jats:styled-content>\n                      ).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of 1054 pregnancies meeting the inclusion criteria, the incidence of neonatal\n                      <jats:styled-content style=\"fixed-case\">SGA<\/jats:styled-content>\n                      was 139 (13.2%), and a composite adverse neonatal outcome occurred in 300 (28.4%). The sensitivity of the customized standard (38.8%) was higher than that of\n                      <jats:styled-content style=\"fixed-case\">IG<\/jats:styled-content>\n                      \u201021 (24.5%) for predicting neonatal\n                      <jats:styled-content style=\"fixed-case\">SGA<\/jats:styled-content>\n                      , with\n                      <jats:styled-content style=\"fixed-case\">AUC<\/jats:styled-content>\n                      (95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      ) of 0.67 (0.63\u20100.71) for customized vs 0.62 (0.58\u20100.65) for\n                      <jats:styled-content style=\"fixed-case\">IG<\/jats:styled-content>\n                      \u201021;\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a0.003. Both standards were comparable in predicting the composite adverse neonatal outcomes:\n                      <jats:styled-content style=\"fixed-case\">AUC<\/jats:styled-content>\n                      (95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      ) 0.52 (0.50\u20100.55) for customized vs 0.51 (0.50\u20100.53) for\n                      <jats:styled-content style=\"fixed-case\">IG<\/jats:styled-content>\n                      \u201021;\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.25.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Both growth standards had modest performance in detecting neonatal\n                      <jats:styled-content style=\"fixed-case\">SGA<\/jats:styled-content>\n                      and were poor at predicting short\u2010term adverse neonatal outcome.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/aogs.13394","type":"journal-article","created":{"date-parts":[[2018,6,7]],"date-time":"2018-06-07T09:37:36Z","timestamp":1528364256000},"page":"1381-1387","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":35,"title":["Customized fetal growth standard compared with the INTERGROWTH\u201021st century standard at predicting small\u2010for\u2010gestational\u2010age neonates"],"prefix":"10.1111","volume":"97","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4340-450X","authenticated-orcid":false,"given":"Anthony O.","family":"Odibo","sequence":"first","affiliation":[{"name":"Division of Maternal Fetal Medicine Department of Obstetrics and Gynecology University of South Florida Morsani College of Medicine Tampa FL 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