{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T03:03:29Z","timestamp":1782788609333,"version":"3.54.5"},"reference-count":16,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,8,2]],"date-time":"2018-08-02T00:00:00Z","timestamp":1533168000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Ultrasound signs of abnormal placental invasion are subjective in nature. We tested the hypothesis that placental thickness in the lower uterine segment is increased when there is abnormally invasive placenta (<jats:styled-content style=\"fixed-case\">AIP<\/jats:styled-content>) in women with a low\u2010lying placenta.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>Retrospective analysis of data of placental thickness in women with ultrasound evidence of major placenta previa or a low\u2010lying anterior placenta was done. The diagnosis of <jats:styled-content style=\"fixed-case\">AIP<\/jats:styled-content> was confirmed both intraoperatively and on histopathology for those managed by partial myometrial excision with uterine conservation or by hysterectomy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In all, 131 records were available for analysis after exclusion of 33 cases due to unsuitable images and eight cases without pregnancy outcomes. The diagnosis of <jats:styled-content style=\"fixed-case\">AIP<\/jats:styled-content> was confirmed in 28 (21.4%) of the 131 cases. The lower segment placental thickness was significantly higher in women with <jats:styled-content style=\"fixed-case\">AIP<\/jats:styled-content> (median\u00a0=\u00a050.3\u00a0mm, <jats:styled-content style=\"fixed-case\">IQR<\/jats:styled-content>: 42.7\u201064.3) than in those with normal placentation (median\u00a0=\u00a030.9\u00a0mm, <jats:styled-content style=\"fixed-case\">IQR<\/jats:styled-content>: 22.9\u201042.2, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001). Logistic regression analysis showed that previous cesarean section and placental thickness on ultrasound were independent predictors for <jats:styled-content style=\"fixed-case\">AIP<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Lower uterine segment placental thickness is increased in women with <jats:styled-content style=\"fixed-case\">AIP<\/jats:styled-content> compared with those with noninvasive placentation. This association constitutes a pragmatic objective sign and may be of clinical value in improving prenatal detection of <jats:styled-content style=\"fixed-case\">AIP<\/jats:styled-content> in women with placental implantation in the lower uterine segment. Prospective studies are necessary to ascertain lower segment placental thickness as a predictor for <jats:styled-content style=\"fixed-case\">AIP<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aogs.13422","type":"journal-article","created":{"date-parts":[[2018,7,6]],"date-time":"2018-07-06T07:20:57Z","timestamp":1530861657000},"page":"95-100","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Lower uterine segment placental thickness in women with abnormally invasive placenta"],"prefix":"10.1111","volume":"98","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2393-7501","authenticated-orcid":false,"given":"Amarnath","family":"Bhide","sequence":"first","affiliation":[{"name":"Department of Obstetrics &amp; Gynecology St George's University Hospital Foundation Trust, University of London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2648-195X","authenticated-orcid":false,"given":"Arianna","family":"Laoreti","sequence":"additional","affiliation":[{"name":"Department of Obstetrics &amp; Gynecology St George's University Hospital Foundation Trust, University of London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Kaelin Agten","sequence":"additional","affiliation":[{"name":"Department of Obstetrics &amp; Gynecology St George's University Hospital Foundation Trust, University of London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aris","family":"Papageorghiou","sequence":"additional","affiliation":[{"name":"Department of Obstetrics &amp; Gynecology St George's University Hospital Foundation Trust, University of London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2802-7670","authenticated-orcid":false,"given":"Asma","family":"Khalil","sequence":"additional","affiliation":[{"name":"Department of Obstetrics &amp; Gynecology St George's University Hospital Foundation Trust, University of London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7364-346X","authenticated-orcid":false,"given":"James","family":"Uprichard","sequence":"additional","affiliation":[{"name":"Department of Hematology St George's University Hospital Foundation Trust, University of London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5531-4301","authenticated-orcid":false,"given":"Basky","family":"Thilaganathan","sequence":"additional","affiliation":[{"name":"Department of Obstetrics &amp; Gynecology St George's University Hospital Foundation Trust, University of London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5711-8515","authenticated-orcid":false,"given":"Edwin","family":"Chandraharan","sequence":"additional","affiliation":[{"name":"Department of Obstetrics &amp; Gynecology St George's University Hospital Foundation Trust, University of London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,8,2]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000207559.15715.98"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000001005"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2011.11.010"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0412.2011.01147.x"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.13194"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2017.02.050"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.13282"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.7863\/jum.2005.24.11.1569"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.16216"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2003.11.024"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.7863\/jum.1992.11.7.333"},{"key":"e_1_2_9_13_1","unstructured":"JohnsonT Paterson\u2010BrownS.Placenta praevia placenta praevia accreta and vasa praevia: diagnosis and management. 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