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Junctional zone maximum thickness (<jats:styled-content style=\"fixed-case\">JZ<\/jats:styled-content><jats:sub>max<\/jats:sub>), junctional zone maximum irregularity (<jats:styled-content style=\"fixed-case\">JZ<\/jats:styled-content><jats:sub>dif<\/jats:sub>) and ultrasonographic characteristics of adenomyosis were compared with histopathology of the junctional zone defined as (1) adenomyosis of the inner myometrium, \u22652\u00a0mm myometrial invasion without contact to the basal endometrium, (2) serrated junctional zone, &gt;3\u00a0mm myometrial invasion with contact to the basal endometrium or (3) linear junctional zone, no or marginal myometrial invasion \u22643\u00a0mm with contact to the basal endometrium.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Adenomyosis of the inner myometrium, serrated junctional zone and linear junctional zone was present in 29%, 35% and 35% of the women, respectively. Median <jats:styled-content style=\"fixed-case\">JZ<\/jats:styled-content><jats:sub>max<\/jats:sub> and median <jats:styled-content style=\"fixed-case\">JZ<\/jats:styled-content><jats:sub>dif<\/jats:sub> expanded from linear junctional zone (8.5 and 3.3\u00a0mm) to serrated junctional zone (10.1 and 4.1\u00a0mm) to adenomyosis of the inner myometrium (14.6 and 9.2\u00a0mm) (<jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.05). In addition, the median number of characteristic adenomyosis\u2010like ultrasonographic features increased from the linear junctional zone to the serrated junctional zone to adenomyosis of the inner myometrium (<jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>A slightly thickened and\/or irregular junctional zone corresponds to a histopathologically defined serrated junctional zone. This study emphasizes three distinct appearances of the junctional zone: adenomyosis of the inner myometrium, junctional zone disease (serrated junctional zone) and linear junctional zone. This classification may be useful in future clinical studies.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aogs.13484","type":"journal-article","created":{"date-parts":[[2018,10,14]],"date-time":"2018-10-14T09:38:37Z","timestamp":1539509917000},"page":"205-214","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Two\u2010 and three\u2010dimensional ultrasonographic features related to histopathology of the uterine endometrial\u2010myometrial junctional zone"],"prefix":"10.1111","volume":"98","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1813-1028","authenticated-orcid":false,"given":"Christina Kjaergaard","family":"Rasmussen","sequence":"first","affiliation":[{"name":"Department of Gynecology and Obstetrics Aarhus University Hospital Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7808-908X","authenticated-orcid":false,"given":"Estrid Staehr","family":"Hansen","sequence":"additional","affiliation":[{"name":"Department of Pathology Aarhus University Hospital Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2577-7903","authenticated-orcid":false,"given":"Margit","family":"Dueholm","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics Aarhus University Hospital Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,11,25]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1472-6483(10)60201-5"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.6432"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.141.6.1119"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.171.1.2928531"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-014-3437-8"},{"key":"e_1_2_10_7_1","first-page":"125","article-title":"A new concept of endometriosis and adenomyosis: tissue injury and repair (TIAR)","volume":"5","author":"Leyendecker G","year":"2011","journal-title":"Horm Mol Biol Clin Invest"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-009-1191-0"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/1933719116687855"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpobgyn.2006.02.001"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2010.03.015"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.14806"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.8900"},{"key":"e_1_2_10_14_1","first-page":"208","volume-title":"The corpus uteri. 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