{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T17:13:02Z","timestamp":1792602782801,"version":"4.5.0"},"reference-count":28,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,2,3]],"date-time":"2019-02-03T00:00:00Z","timestamp":1549152000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004756","name":"Emil Aaltosen S\u00e4\u00e4ti\u00f6","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004756","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003125","name":"Suomen Kulttuurirahasto","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003125","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005438","name":"H\u00e4meen Rahasto","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005438","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2019,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The management of pelvic organ prolapse (<jats:styled-content style=\"fixed-case\">POP<\/jats:styled-content>) varies significantly between countries. The objective of this study was to describe the methods used for <jats:styled-content style=\"fixed-case\">POP<\/jats:styled-content> surgery in Finland and to identify the factors that affect clinicians\u2019 choice to use either a native tissue repair (<jats:styled-content style=\"fixed-case\">NTR<\/jats:styled-content>) or a mesh repair method.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and Methods<\/jats:title><jats:p>This prospective cohort study included 3535 surgeries covering 83% of all <jats:styled-content style=\"fixed-case\">POP<\/jats:styled-content> operations performed in Finland in 2015. The operative details and patient characteristics, including the Pelvic Floor Distress Inventory (<jats:styled-content style=\"fixed-case\">PFDI<\/jats:styled-content>\u201020), were compared between three selected surgical methods: <jats:styled-content style=\"fixed-case\">NTR<\/jats:styled-content>, transvaginal mesh (<jats:styled-content style=\"fixed-case\">TVM<\/jats:styled-content>) and abdominal mesh (<jats:styled-content style=\"fixed-case\">AM<\/jats:styled-content>). The predictive factors for the use of mesh augmentation were also studied with logistic regression analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The most common method was <jats:styled-content style=\"fixed-case\">NTR<\/jats:styled-content> (n\u00a0=\u00a02855, 81%), followed by <jats:styled-content style=\"fixed-case\">TVM<\/jats:styled-content> (n\u00a0=\u00a0429, 12%) and <jats:styled-content style=\"fixed-case\">AM<\/jats:styled-content> (n\u00a0=\u00a0251, 7%). Approximately 92% of the patients who underwent primary prolapse surgery underwent <jats:styled-content style=\"fixed-case\">NTR<\/jats:styled-content>, and mesh surgery was used mainly for recurrent prolapse. The strongest predictor of mesh surgery was previous <jats:styled-content style=\"fixed-case\">POP<\/jats:styled-content> surgery for the same vaginal compartment (adjusted odds ratio [<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>]\u00a0=\u00a056, 95% confidence interval [<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>]\u00a0=\u00a038\u201084 for <jats:styled-content style=\"fixed-case\">TVM<\/jats:styled-content>; adjusted <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\u00a0=\u00a022, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\u00a0=\u00a014\u201034 for <jats:styled-content style=\"fixed-case\">AM<\/jats:styled-content>). Other predictive factors for mesh surgery were previous hysterectomy, healthcare district, severe bulge symptoms and advanced prolapse. <jats:styled-content style=\"fixed-case\">TVM<\/jats:styled-content> was associated with advanced anterior prolapse and older age. <jats:styled-content style=\"fixed-case\">AM<\/jats:styled-content> surgery was associated with advanced apical and\/or posterior compartment prolapse. <jats:styled-content style=\"fixed-case\">PFDI<\/jats:styled-content>\u201020 scores were the highest in the <jats:styled-content style=\"fixed-case\">AM<\/jats:styled-content> group (108 vs 103 in the <jats:styled-content style=\"fixed-case\">TVM<\/jats:styled-content> group and 98 in the <jats:styled-content style=\"fixed-case\">NTR<\/jats:styled-content> group, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.012), which indicates more bothersome symptoms than in the other groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The Finnish practices follow international guidelines that advocate <jats:styled-content style=\"fixed-case\">NTR<\/jats:styled-content> as the principal surgical method for <jats:styled-content style=\"fixed-case\">POP<\/jats:styled-content>. Synthetic mesh augmentation was mainly used in patients with recurrent and advanced prolapse with severe symptoms. The variation in the rates of mesh augmentation for <jats:styled-content style=\"fixed-case\">POP<\/jats:styled-content> surgery in different hospitals implies a lack of sufficient evidence of the most suitable treatment method and indicates a need for national guidelines.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aogs.13520","type":"journal-article","created":{"date-parts":[[2018,12,22]],"date-time":"2018-12-22T05:10:06Z","timestamp":1545455406000},"page":"451-459","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Methods of surgery for pelvic organ prolapse in a nationwide cohort (<scp>FINPOP<\/scp> 2015)"],"prefix":"10.1111","volume":"98","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2304-3938","authenticated-orcid":false,"given":"Nina K.","family":"Mattsson","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Kanta\u2010H\u00e4me Central Hospital H\u00e4meenlinna Finland"},{"name":"Institute of Clinical Medicine University of Eastern Finland Kuopio Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2271-1773","authenticated-orcid":false,"given":"P\u00e4ivi","family":"Karjalainen","sequence":"additional","affiliation":[{"name":"Institute of Clinical Medicine University of Eastern Finland Kuopio Finland"},{"name":"Department of Obstetrics and Gynecology Central Finland Central Hospital  Jyv\u00e4skyl\u00e4 Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9270-9268","authenticated-orcid":false,"given":"Anna\u2010Maija","family":"Tolppanen","sequence":"additional","affiliation":[{"name":"School of Pharmacy University of Eastern Finland Kuopio Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna\u2010Mari","family":"Heikkinen","sequence":"additional","affiliation":[{"name":"Institute of Clinical Medicine University of Eastern Finland Kuopio Finland"},{"name":"Terveystalo Kuopio Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7452-442X","authenticated-orcid":false,"given":"Jyrki","family":"Jalkanen","sequence":"additional","affiliation":[{"name":"Central Finland Hospital District Jyv\u00e4skyl\u00e4 Finland"},{"name":"Faculty of Medicine and Life Sciences University of Tampere Tampere Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P\u00e4ivi","family":"H\u00e4rkki","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Helsinki University Hospital and Helsinki University  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kari","family":"Nieminen","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Life Sciences University of Tampere Tampere Finland"},{"name":"Department of Obstetrics and Gynecology Tampere University Hospital  Tampere Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,2,3]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000000286"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(97)00058-6"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2017.04.004"},{"key":"e_1_2_10_5_1","unstructured":"Finnish National Institute for Health and Welfare.Somatic special health care in Finland 2014\u20102015.http:\/\/www.julkari.fi\/bitstream\/handle\/10024\/132354\/Tr10_17.pdf?sequence=1. 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