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However, less is known about the possible association of placental location other than previa with pregnancy outcomes. The aim of this study was to investigate if placental location other than previa is associated with adverse pregnancy, delivery and infant outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>This is a population\u2010based cohort study, with data from the regional population\u2010based Stockholm\u2010Gotland Obstetric Cohort, Sweden, from 2008 to 2014. The study population included 74\u00a0087 nulliparous women with singleton pregnancies resulting in live\u2010born infants, with information about placental location from the second\u2010trimester ultrasound screening. The association between placental location (fundal, lateral, anterior or posterior) and pregnancy outcomes was estimated using logistic regression analysis. Odds ratios (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>) with 95% confidence intervals (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>) were calculated, and adjustments were made for maternal age, height, country of birth, smoking in early pregnancy, sex of the infant and in vitro fertilization. Main outcome measures were pregnancy, delivery and infant outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Compared with posterior placental location, fundal and lateral placental locations were associated with a number of adverse pregnancy outcomes, the most important being: very preterm birth (&lt;32\u00a0weeks of gestation) (adjusted <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> [<jats:styled-content style=\"fixed-case\">aOR<\/jats:styled-content>] 1.78, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.18\u20102.63 and aOR 2.12, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.39\u20102.25, respectively), moderate preterm birth (32\u201036\u00a0weeks of gestation) (<jats:styled-content style=\"fixed-case\">aOR<\/jats:styled-content> 1.23, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.001\u20101.51 and aOR 1.62, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.32\u20102.00, respectively), small\u2010for\u2010gestational\u2010age birth (<jats:styled-content style=\"fixed-case\">aOR<\/jats:styled-content> 1.67, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.34\u20102.07 and aOR 1.77, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.39\u20102.25, respectively) and manual removal of the placenta in vaginal births (<jats:styled-content style=\"fixed-case\">aOR<\/jats:styled-content> 3.27, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 2.68\u20103.99 and aOR 3.27, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 2.60\u20104.10, respectively). Additionally, lateral placental location was associated with preeclampsia (<jats:styled-content style=\"fixed-case\">aOR<\/jats:styled-content> 1.30, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.03\u20101.65) and severe postpartum hemorrhage (<jats:styled-content style=\"fixed-case\">aOR<\/jats:styled-content> 1.42, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.27\u20101.82).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Compared with posterior placental location, fundal and lateral placental locations are associated with a number of adverse pregnancy, delivery and infant outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aogs.13578","type":"journal-article","created":{"date-parts":[[2019,2,15]],"date-time":"2019-02-15T08:48:31Z","timestamp":1550220511000},"page":"988-996","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Placental location and pregnancy outcomes in nulliparous women: A population\u2010based cohort study"],"prefix":"10.1111","volume":"98","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6311-9506","authenticated-orcid":false,"given":"Michaela","family":"Granfors","sequence":"first","affiliation":[{"name":"Department of Medicine, Solna Clinical Epidemiology Division Karolinska Institutet Stockholm Sweden"},{"name":"Department of Clinical Science Karolinska Institutet Danderyd Hospital Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1528-4563","authenticated-orcid":false,"given":"Olof","family":"Stephansson","sequence":"additional","affiliation":[{"name":"Department of Medicine, Solna Clinical Epidemiology Division Karolinska Institutet Stockholm Sweden"},{"name":"Department of Women's and Children's Health Division of Obstetrics and Gynecology Karolinska Institutet Stockholm 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