{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T07:03:44Z","timestamp":1773299024153,"version":"3.50.1"},"reference-count":14,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,9,25]],"date-time":"2019-09-25T00:00:00Z","timestamp":1569369600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2020,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>To assess the clinical impact of preoperative fludeoxyglucose (FDG) with positron emission tomography (PET) and computed tomography (CT) in women with ovarian, fallopian tube, or peritoneal cancer with focus on consequences of added findings (AFs).<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>FDG\u2010PET\/CT was implemented as a standard imaging modality for women with newly diagnosed ovarian, fallopian tube, or peritoneal cancer at our institution in 2008. After full implementation, all preoperative scans were reviewed and AFs were evaluated from January 2011 to December 2012. Decisions regarding further examination made at the first multidisciplinary team conference were recorded. Subsequent procedures were tracked via medical records, and the impact of AFs on additional examinations, delay, and change in treatment plans was evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Forty\u2010four (21.1%) of 209 women presented with AFs. Further examination was performed in 35\/44 (79.5%). Malignancy was identified in 15\/35 (42.9%), revealing metastases from ovarian, fallopian tube, or peritoneal cancer in 11, a synchronous primary cancer in 3, and recurrence of a previous cancer in 1 woman. The ovarian, fallopian tube, or peritoneal cancer metastases were localized in the lungs, uterus, colon, vagina, and breasts. The remaining 20 AFs revealed 2 benign lesions and 1 pre\u2010malignant lesion, whereas no abnormality was found in 17. Further examination of AFs resulted in a significant time delay until treatment start of median 4\u00a0days (range 1\u201083\u00a0days, <jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.004).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Further examinations of AFs by FDG\u2010PET\/CT delayed time to start of treatment by median 4\u00a0days in women with newly diagnosed ovarian, fallopian tube, or peritoneal cancer in a contemporary institution with fast\u2010track access to additional diagnostics. The clinical implications of this must be balanced against the gain of detecting unrecognized malignancy in 15 of 209 women (7.2%).<\/jats:p><\/jats:sec>","DOI":"10.1111\/aogs.13726","type":"journal-article","created":{"date-parts":[[2019,9,10]],"date-time":"2019-09-10T17:28:28Z","timestamp":1568136508000},"page":"186-195","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Clinical impact of pre\u2010treatment FDG\u2010PET\/CT staging of primary ovarian, fallopian tube, and peritoneal cancers in women"],"prefix":"10.1111","volume":"99","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0679-2702","authenticated-orcid":false,"given":"Sara E.","family":"Sponholtz","sequence":"first","affiliation":[{"name":"Faculty of Health Sciences Institute of Clinical Research Research Unit of Gynecology and Obstetrics Odense University Hospital University of Southern Denmark Odense Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ole","family":"Mogensen","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences Institute of Clinical Research Research Unit of Gynecology and Obstetrics Odense University Hospital University of Southern Denmark Odense Denmark"},{"name":"Faculty of Health Institute for Clinical Medicine Aarhus University Aarhus Denmark"},{"name":"Department of Gynecology Aarhus University Hospital Aarhus Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Malene G.","family":"Hildebrandt","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine Odense University Hospital Odense Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pernille T.","family":"Jensen","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences Institute of Clinical Research Research Unit of Gynecology and Obstetrics Odense University Hospital University of Southern Denmark Odense Denmark"},{"name":"Faculty of Health Institute for Clinical Medicine Aarhus University Aarhus Denmark"},{"name":"Department of Gynecology Aarhus University Hospital Aarhus Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,9,25]]},"reference":[{"key":"e_1_2_9_2_1","volume-title":"Pakkeforl\u00f8b for kr\u00e6ft i \u00e6ggestokkene. For fagfolk. [Disease management program for ovarian cancer. For professionals]","author":"Sundhedsstyrelsen","year":"2019"},{"key":"e_1_2_9_3_1","volume-title":"Retningslinier for visitation, diagnostik, behandling og opf\u00f8lgning af epitelial ovarie\u2010, tuba\u2010 og prim\u00e6r peritonealcancer samt borderline tumorer. [Guidelines for visitation, diagnostics, treatment and follow\u2010up of ovarian, fallopian tube and peritoneal cancer]","author":"Dansk Gyn\u00e6kologisk Cancer Gruppe","year":"2016"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2009.03.051"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.crad.2010.12.004"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdt333"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rcl.2013.07.006"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10555-013-9456-2"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpet.2014.09.007"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2008.12.015"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2009.04.024"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/MNM.0b013e328332b30e"},{"issue":"5","key":"e_1_2_9_13_1","first-page":"752","article-title":"Detection of unexpected additional primary malignancies with PET\/CT","volume":"46","author":"Ishimori T","year":"2005","journal-title":"J Nucl Med"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1259\/bjr\/60606623"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1259\/bjr\/98067945"}],"container-title":["Acta Obstetricia et Gynecologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Faogs.13726","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aogs.13726","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/aogs.13726","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aogs.13726","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,7]],"date-time":"2023-09-07T20:21:06Z","timestamp":1694118066000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/aogs.13726"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9,25]]},"references-count":14,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,2]]}},"alternative-id":["10.1111\/aogs.13726"],"URL":"https:\/\/doi.org\/10.1111\/aogs.13726","archive":["Portico"],"relation":{},"ISSN":["0001-6349","1600-0412"],"issn-type":[{"value":"0001-6349","type":"print"},{"value":"1600-0412","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,9,25]]},"assertion":[{"value":"2019-04-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-09-04","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-09-25","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}