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The purpose of this study was to examine a large cohort of women delivering a multiple pregnancy in a single large tertiary unit, and to evaluate the implications of hypertensive disorders of pregnancy on both maternal and perinatal outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>Retrospective study of all twin pregnancies delivered at Cork University Maternity Hospital, Ireland over a 9\u2010year period (2009\u20102017). The twin pregnancies were divided according to the presence or absence of hypertensive disorder of pregnancy and the two groups were compared.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Maternal age &gt;40\u00a0years, nulliparity, conception through use of a donor oocyte, and presence of obstetric cholestasis are all risk factors for the development of hypertensive disorders of pregnancy in women with a multiple pregnancy. When a hypertensive disorder complicates a twin pregnancy, it increases the incidence of iatrogenic late prematurity and neonatal hypoglycemia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study is informative for clinicians caring for women with a multiple pregnancy with its relevant data on perinatal outcomes following a diagnosis of hypertensive disorder in pregnancy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aogs.13774","type":"journal-article","created":{"date-parts":[[2019,11,23]],"date-time":"2019-11-23T18:08:56Z","timestamp":1574532536000},"page":"525-536","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["The maternal and perinatal implications of hypertensive disorders of pregnancy in a multiple pregnancy cohort"],"prefix":"10.1111","volume":"99","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2490-3661","authenticated-orcid":false,"given":"Deirdre","family":"Hayes\u2010Ryan","sequence":"first","affiliation":[{"name":"The Irish Center for Maternal and Child Health Research University College Cork Cork Ireland"},{"name":"Department of Obstetrics &amp; Gynecology Cork University Maternity Hospital Cork Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah","family":"Meaney","sequence":"additional","affiliation":[{"name":"National Perinatal Epidemiology Center University College Cork Cork Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aoibhin","family":"Hodnett","sequence":"additional","affiliation":[{"name":"The Irish Center for Maternal and Child Health Research University College Cork Cork Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minna","family":"Geisler","sequence":"additional","affiliation":[{"name":"Department of Obstetrics &amp; Gynecology Cork University Maternity Hospital Cork Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keelin","family":"O'Donoghue","sequence":"additional","affiliation":[{"name":"The Irish Center for Maternal and Child Health Research University College Cork Cork Ireland"},{"name":"Department of Obstetrics &amp; Gynecology Cork University Maternity Hospital Cork Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,1,20]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.117.10803"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.3109\/14767058.2016.1174209"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)68397-9"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)14237-7"},{"issue":"3","key":"e_1_2_9_6_1","first-page":"70","article-title":"Trends in the obstetric features and management of twin pregnancies","volume":"103","author":"Smith KE","year":"2010","journal-title":"Ir Med J"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.siny.2010.06.004"},{"key":"e_1_2_9_8_1","volume-title":"Clinical Guideline [CG129]. 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