{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T08:16:52Z","timestamp":1780474612489,"version":"3.54.1"},"reference-count":22,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2020,6,3]],"date-time":"2020-06-03T00:00:00Z","timestamp":1591142400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The uterocervical angle has been proposed as an ultrasound marker to predict spontaneous preterm birth; however, the studies that provided this evidence were retrospective and their results heterogeneous. This study aimed to assess the ability of the uterocervical angle to predict spontaneous preterm birth before 34 and 37\u00a0weeks of gestation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>A prospective cohort study with singleton pregnancies between 19.0 and 22.6\u00a0weeks of gestation. Uterocervical angle and cervical length were measured by transvaginal ultrasound. Maternal history and pregnancy data were recorded. Delivery data were subsequently collected.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The final analysis included 1453 singleton pregnancies. Spontaneous preterm birth before 37\u00a0weeks occurred in 52 cases (3.6%) and before 34\u00a0weeks in 17 (1.2%). For the prediction of spontaneous preterm birth before 34\u00a0weeks, the area under the curve for the uterocervical angle was 0.67 (95% CI 0.54\u20100.79) and the detection rates were 5.9% and 23.5% for fixed false\u2010positive rates of 5% and 10%, respectively. For the prediction of spontaneous preterm birth before 37\u00a0weeks, the area under the curve was 0.58 (95% CI 0.50\u20100.67) and the detection rates were 5.8% and 18% for fixed false\u2010positive rates of 5% and 10%, respectively. Combined predictive models were studied. To predict spontaneous preterm birth before 34\u00a0weeks, the best model was provided by a combination of uterocervical angle and cervical length (area under the curve 0.72; 95% CI 0.58\u20100.86). The detection rates of this model were 35.3% and 41.2% for fixed false\u2010positive rates of 5% and 10%, respectively. To predict spontaneous preterm birth before 37\u00a0weeks of gestation, the best model was provided by a combination of uterocervical angle, cervical length, and previous history of spontaneous preterm birth (area under the curve 0.64; 95% CI 0.55\u20100.72). The detection rates of this model were 15.4% and 30.8% for fixed false\u2010positive rates of 5% and 10%, respectively. Obese women and those with a history of cesarean section had a wider uterocervical angle.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The uterocervical angle, measured mid\u2010trimester, is a poor predictor of spontaneous preterm birth.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aogs.13879","type":"journal-article","created":{"date-parts":[[2020,4,20]],"date-time":"2020-04-20T22:31:16Z","timestamp":1587421876000},"page":"1511-1518","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Prospective evaluation of the uterocervical angle as a predictor of spontaneous preterm birth"],"prefix":"10.1111","volume":"99","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2100-7693","authenticated-orcid":false,"given":"Alba","family":"Farr\u00e0s Llobet","sequence":"first","affiliation":[{"name":"Maternal and Fetal Medicine Group Vall d\u2019Hebron Institut de Recerca (VHIR) Vall d\u2019Hebron Hospital Universitari Vall d\u2019Hebron Barcelona Hospital Campus Barcelona Spain"},{"name":"Maternal and Fetal Medicine Unit Vall d\u2019Hebron Hospital Universitari Vall d\u2019Hebron Barcelona Hospital Campus Barcelona Spain"},{"name":"Universitat Aut\u00f2noma de Barcelona Bellaterra Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teresa","family":"Higueras","sequence":"additional","affiliation":[{"name":"Maternal and Fetal Medicine Group Vall d\u2019Hebron Institut de Recerca (VHIR) Vall d\u2019Hebron Hospital Universitari Vall d\u2019Hebron Barcelona Hospital Campus Barcelona Spain"},{"name":"Maternal and Fetal Medicine Unit Vall d\u2019Hebron Hospital Universitari Vall d\u2019Hebron Barcelona Hospital Campus Barcelona Spain"},{"name":"Universitat Aut\u00f2noma de Barcelona Bellaterra Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"In\u00e9s Z.","family":"Calero","sequence":"additional","affiliation":[{"name":"Maternal and Fetal Medicine Group Vall d\u2019Hebron Institut de Recerca (VHIR) Vall d\u2019Hebron Hospital Universitari Vall d\u2019Hebron Barcelona Hospital Campus Barcelona Spain"},{"name":"Maternal and Fetal Medicine Unit Vall d\u2019Hebron Hospital Universitari Vall d\u2019Hebron Barcelona Hospital Campus Barcelona Spain"},{"name":"Universitat Aut\u00f2noma de Barcelona Bellaterra Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laia","family":"Reginc\u00f3s Mart\u00ed","sequence":"additional","affiliation":[{"name":"Maternal and Fetal Medicine Unit Vall d\u2019Hebron Hospital Universitari Vall d\u2019Hebron Barcelona Hospital Campus Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8261-6383","authenticated-orcid":false,"given":"Nerea","family":"Maiz","sequence":"additional","affiliation":[{"name":"Maternal and Fetal Medicine Group Vall d\u2019Hebron Institut de Recerca (VHIR) Vall d\u2019Hebron Hospital Universitari Vall 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