{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T13:28:41Z","timestamp":1790861321580,"version":"4.1.0"},"reference-count":21,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2020,6,19]],"date-time":"2020-06-19T00:00:00Z","timestamp":1592524800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003252","name":"Lunds Universitet","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003252","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Obstetricians routinely use biochemical parameters from non\u2010pregnant women to assess the condition of the laboring mother. However, it is well known that pregnancy leads to significant physiological changes in most organ systems. The aim of this study was to determine normal values for maternal arterial blood gases during vaginal deliveries as compared with control values from planned cesarean sections. We also wanted to elucidate the effect of various maternal characteristics, mode of delivery and obstetric interventions on blood gas values.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and methods<\/jats:title>\n                    <jats:p>We carried out a randomly selected, prospective\u2010observational cohort study of 250 women undergoing vaginal delivery and 58 women undergoing planned cesarean section at the Department of Obstetrics and Gynecology, Sk\u00e5ne University Hospital, Malm\u00f6, Sweden.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      We found significant differences for gestational age, parity, umbilical venous blood pH, pCO\n                      <jats:sub>2<\/jats:sub>\n                      and lactate values between the two study groups (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a0.005). Significantly lower pH, pCO\n                      <jats:sub>2<\/jats:sub>\n                      , pO\n                      <jats:sub>2<\/jats:sub>\n                      and sO\n                      <jats:sub>2<\/jats:sub>\n                      were found in mothers delivering vaginally. Higher base deficit, hemoglobin, bilirubin, potassium, glucose and lactate were found in vaginal deliveries than in planned cesarean sections (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a0.02). Maternal body mass index (BMI), smoking and hypertension were not significantly correlated to acid base parameters in women with vaginal deliveries. On the other hand, multiple regression showed significant associations for the use of epidural anesthesia on maternal pH (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a0.05) and pO\n                      <jats:sub>2<\/jats:sub>\n                      (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a0.01); and synthetic oxytocin on pCO\n                      <jats:sub>2<\/jats:sub>\n                      (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a0.08), glucose (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a0.00) and lactate (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a0.02) levels in maternal arterial blood. Maternal arterial pH, pCO\n                      <jats:sub>2<\/jats:sub>\n                      and lactate values correlated significantly to values in venous umbilical cord blood (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a0.000).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Maternal arterial blood gas parameters varied significantly according to mode of delivery, the use of epidural anesthesia and synthetic oxytocin.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/aogs.13936","type":"journal-article","created":{"date-parts":[[2020,6,11]],"date-time":"2020-06-11T03:29:34Z","timestamp":1591846174000},"page":"1674-1681","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Maternal arterial blood gas values during delivery: Effect of mode of delivery, maternal characteristics, obstetric interventions and correlation to fetal umbilical cord blood"],"prefix":"10.1111","volume":"99","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0129-1578","authenticated-orcid":false,"given":"Mehreen","family":"Zaigham","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Institution of Clinical Sciences Malm\u00f6 Lund University Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Helfer","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Institution of Clinical Sciences Malm\u00f6 Lund University Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3209-2459","authenticated-orcid":false,"given":"Karl Heby","family":"Kristensen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Institution of Clinical Sciences Malm\u00f6 Lund University Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Per\u2010Erik","family":"Isberg","sequence":"additional","affiliation":[{"name":"Department of Statistics Lund University Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9032-5428","authenticated-orcid":false,"given":"Nana","family":"Wiberg","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Institution of Clinical Sciences Malm\u00f6 Lund University Lund Sweden"},{"name":"Department of Gynecology and Obstetrics Sk\u00e5ne University Hospital Ystad Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,6,19]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.5830\/CVJA-2016-021"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1515\/CCLM.2010.033"},{"key":"e_1_2_10_4_1","first-page":"2607","article-title":"Evaluation of point\u2010of\u2010care maternal venous lactate testing in normal pregnancy","volume":"29","author":"Maguire PJ","year":"2016","journal-title":"J Matern Fetal Neonatal Med"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.13867"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph16112015"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2007.07.016"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.reprotox.2009.03.012"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12884-019-2365-9"},{"key":"e_1_2_10_10_1","first-page":"194","article-title":"Effect of epidural anesthesia for cesarean delivery on maternal femoral arterial and venous, uteroplacental, and umbilical blood flow velocities and waveforms","volume":"75","author":"Baumann H","year":"1990","journal-title":"Obstet Gynecol"},{"key":"e_1_2_10_11_1","first-page":"CD000331","article-title":"Epidural versus non\u2010epidural or no analgesia for pain management in labor","volume":"5","author":"Anim\u2010Somuah M","year":"2018","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1080\/14767058.2016.1181167"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2006.05.043"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0412.2011.01364.x"},{"key":"e_1_2_10_15_1","unstructured":"Radiometer ABL Reference Manual \u2010 Radiometer [Internet]. Available from:https:\/\/www.radiometer.com\/en\/products\/blood\u2010gas\u2010testing\/abl800\u2010flex\u2010blood\u2010gas\u2010analyzer(accessed 1 May 2020)."},{"key":"e_1_2_10_16_1","volume-title":"Perinatal acid\u2010base balance","author":"Rooth G.","year":"1988"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003081-199303000-00004"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2011-1979"},{"key":"e_1_2_10_19_1","first-page":"CD009701","article-title":"High\u2010dose versus low\u2010dose oxytocin infusion regimens for induction of labor at term","volume":"10","author":"Budden A","year":"2014","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2001.00034.x"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(99)70083-9"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0412.2011.01237.x"}],"container-title":["Acta Obstetricia et Gynecologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Faogs.13936","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aogs.13936","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/aogs.13936","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aogs.13936","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,30]],"date-time":"2023-08-30T10:55:20Z","timestamp":1693392920000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/aogs.13936"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,19]]},"references-count":21,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2020,12]]}},"alternative-id":["10.1111\/aogs.13936"],"URL":"https:\/\/doi.org\/10.1111\/aogs.13936","archive":["Portico"],"relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2020.02.14.950089","asserted-by":"object"}]},"ISSN":["0001-6349","1600-0412"],"issn-type":[{"value":"0001-6349","type":"print"},{"value":"1600-0412","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,6,19]]},"assertion":[{"value":"2020-03-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-06-03","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-06-19","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}