{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T21:29:28Z","timestamp":1785878968714,"version":"3.56.0"},"reference-count":19,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T00:00:00Z","timestamp":1596240000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The cervical length (CL) measurement is a widely used method to estimate the risk of preterm birth. Due in particular to the high false\u2010positive rate, the establishment of markers with improved test characteristics is a great challenge. A potential predictor of preterm birth is the uterocervical angle (UCA) and this additional measurement may improve the risk assessment. It was the aim of this study to compare the test properties of CL and UCA on patients at risk for preterm birth.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>109 patients with at least one of the following signs of threatening preterm birth between 20<jats:sup>+0\/7<\/jats:sup> and 31<jats:sup>+6\/7<\/jats:sup>\u00a0weeks were included in a prospective cohort analysis: regular (&gt;3\/30\u00a0min) or painful uterine contractions, CL below 25\u00a0mm or a history of preterm birth. Exclusion criteria were premature rupture of membranes, hypertensive disorders, vaginal bleeding, surgical cerclage, Arabin pessary or cervical dilation of more than 30\u00a0mm. The determination of the UCA was carried out in a standardized manner using the image documents captured by vaginal sonographic CL measurement. The primary endpoint was preterm birth &lt;34\u00a0weeks, secondary endpoints were delivery &lt;37\u00a0weeks and within 7\u00a0days.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The UCA was on average 103\u00b0 and the mean UCA in preterm and term groups did not differ significantly (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.924). The UCA was not predictive for threatened preterm birth, even if only singletons were considered. For CL the best predictive accuracy for preterm birth &lt;34\u00a0weeks was observed at a cut\u2010off value of 14\u00a0mm with sensitivity 0.50, specificity 0.80, positive predictive value 0.30, negative predictive value 0.90, positive likelihood ratio 2.4, negative likelihood ratio 0.6 and an odds ratio of 3.9 (95% confidence interval 1.3\u201011.7, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.016).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The assessment of UCA in patients at risk for preterm birth was not suitable to predict the probability of a threatened preterm birth. Measurement of UCA cannot be recommended in this situation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aogs.13955","type":"journal-article","created":{"date-parts":[[2020,7,10]],"date-time":"2020-07-10T19:38:25Z","timestamp":1594409905000},"page":"1527-1533","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Uterocervical angle as a predictor of preterm birth on a high\u2010risk collective between 20 and 31\u00a0weeks of gestation: A cohort analysis"],"prefix":"10.1111","volume":"99","author":[{"given":"Kathleen","family":"Gr\u00fcndler","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology HELIOS Hospital Schwerin Schwerin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernd","family":"Gerber","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Rostock University Medical Center Rostock Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1284-6164","authenticated-orcid":false,"given":"Johannes","family":"Stubert","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Rostock University Medical Center Rostock Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,8]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(18)30451-0"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.7457"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/8367571"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.19119"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.14801"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.12540"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.12507"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2016.03.033"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0037-1608877"},{"key":"e_1_2_10_11_1","unstructured":"National Institute for Health and Care Excellence.Hypertension in pregnancy: diagnosis and management (NG 133): National Institute for Health and Care Excellence.2019.https:\/\/www.nice.org.uk\/guidance\/ng133"},{"key":"e_1_2_10_12_1","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1055\/a-0903-2671","article-title":"Prevention and Therapy of Preterm Birth. Guideline of the DGGG, OEGGG and SGGG (S2k Level, AWMF Registry Number 015\/025, February 2019)\u00a0\u2013\u00a0part 1 with recommendations on the epidemiology, etiology, prediction, primary and secondary prevention of preterm birth","volume":"79","author":"Berger R","year":"2019","journal-title":"Geburtshilfe Frauenheilkd"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.18203\/2320-1770.ijrcog20172114"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1080\/14767058.2017.1331427"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1159\/000447588"},{"issue":"1","key":"e_1_2_10_16_1","first-page":"44","article-title":"The association between anterior uterocervical angle and pregnancy between 16\u201324 weeks of gestation","volume":"28","author":"Chaiwongsa T","year":"2020","journal-title":"Thai J Obstet Gynaecol"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.19750"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2016.11.608"},{"key":"e_1_2_10_19_1","unstructured":"Farr\u00e0s LlobetA Higueras SanzMT Calero Fern\u00e1ndezIZ et al.Second trimester uterocervical angle as a predictor of spontaneous preterm birth: a prospective study. 16th World Congress in Fetal Medicine 2017.https:\/\/fetalmedicine.org\/abstracts\/2017\/var\/pdf\/abstracts\/2017\/2228.pdf"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2017.10.401"}],"container-title":["Acta Obstetricia et Gynecologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Faogs.13955","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aogs.13955","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/aogs.13955","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aogs.13955","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,24]],"date-time":"2023-08-24T13:33:17Z","timestamp":1692883997000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/aogs.13955"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8]]},"references-count":19,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2020,11]]}},"alternative-id":["10.1111\/aogs.13955"],"URL":"https:\/\/doi.org\/10.1111\/aogs.13955","archive":["Portico"],"relation":{},"ISSN":["0001-6349","1600-0412"],"issn-type":[{"value":"0001-6349","type":"print"},{"value":"1600-0412","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8]]},"assertion":[{"value":"2020-04-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-07-06","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-08-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}