{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T11:24:43Z","timestamp":1767007483363,"version":"3.40.5"},"reference-count":36,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2021,1,12]],"date-time":"2021-01-12T00:00:00Z","timestamp":1610409600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The objective of this study was to explore the association between detection of fetal growth restriction and maternal\u2010, healthcare provider\u2010 and organizational factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>A historical, observational, multicentre study. All women who gave birth to a child with a birthweight &lt;2.3rd centile from 1 September 2012 to 31 August 2015 in Zealand, Denmark, were included. The population was identified through the Danish Fetal Medicine Database. Medical charts were reviewed to obtain data regarding maternal characteristics and information on the healthcare professionals. Date of authorization for the midwives and obstetricians involved was extracted from the Danish Health Authorization Registry. Multivariable Cox regression models were used to identify predictors of antenatal detection of fetal growth restriction, and analyses were adjusted for hospital, body mass index, parity, the presence of at least one risk factor and experience of the first midwife, number of midwife visits, number of visits to a doctor, the experience of the consultant midwife or the educational level of the doctor, the number of scans and gaps in continuity of midwife\u2010care. Antenatal detection was defined as an ultrasound estimated fetal weight &lt;2.3rd centile (corresponding to \u22122 standard deviations) prior to delivery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 78 544 pregnancies, 3069 (3.9%) had a fetal growth restriction. Detection occurred in 31% of fetal growth\u2010restricted pregnancies. Clinical experience (defined as years since graduation) of the first consultation midwife was positively associated with detection, with a hazard ratio [HR] of 1.15, 95% confidence interval [CI] 1.03\u20101.28), for every 10\u00a0years of additional experience. The hazard of detection increased with the number of midwife consultations (HR 1.15, 95% CI 1.05\u20101.26) and with multiparity (HR 1.28, 95% CI 1.03\u20101.58). After adjusting for all covariates, an unexplained difference between hospitals (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.01) remained.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The low\u2010risk nullipara may constitute an overlooked group of women at increased risk of antenatal non\u2010detection of fetal growth restriction. Being screened by experienced midwives during early pregnancy and having access to multiple midwife consultations may improve future diagnosis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aogs.14048","type":"journal-article","created":{"date-parts":[[2020,11,21]],"date-time":"2020-11-21T20:34:51Z","timestamp":1605990891000},"page":"893-899","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Why we succeed and fail in detecting fetal growth restriction: A population\u2010based study"],"prefix":"10.1111","volume":"100","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7831-2555","authenticated-orcid":false,"given":"Lisbeth A.","family":"Andreasen","sequence":"first","affiliation":[{"name":"Copenhagen Academy for Medical Education and Simulation Copenhagen Denmark"},{"name":"Department of Clinical Medicine Faculty of Health and Medical Sciences University of Copenhagen Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ann","family":"Tabor","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine Faculty of Health and Medical Sciences University of Copenhagen Copenhagen Denmark"},{"name":"Department of Obstetrics Center of Fetal Medicine and Ultrasound Copenhagen University Hospital Rigshospitalet Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lone Nikoline","family":"N\u00f8rgaard","sequence":"additional","affiliation":[{"name":"Department of Obstetrics Center of Fetal Medicine and Ultrasound Copenhagen University Hospital Rigshospitalet Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5634-2830","authenticated-orcid":false,"given":"Caroline A.","family":"Taks\u00f8e\u2010Vester","sequence":"additional","affiliation":[{"name":"Copenhagen Academy for Medical Education and Simulation Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lone","family":"Krebs","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine Faculty of Health and Medical Sciences University of Copenhagen Copenhagen Denmark"},{"name":"Department of Obstetrics and Gynecology University of Copenhagen Holb\u00e6k Hospital Holb\u00e6k Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Finn S.","family":"J\u00f8rgensen","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine Faculty of Health and Medical Sciences University of Copenhagen Copenhagen Denmark"},{"name":"Department of Obstetrics and Gynecology Fetal Medicine Unit Copenhagen University Hospital Hvidovre Hvidovre Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ida E.","family":"Jepsen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology University of Copenhagen Roskilde Hospital Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heidi","family":"Sharif","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology University of Copenhagen N\u00e6stved Hospital Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helle","family":"Zingenberg","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Copenhagen University Hospital Herlev Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susanne","family":"Rosth\u00f8j","sequence":"additional","affiliation":[{"name":"Department of Public Health Section of Biostatistics University of Copenhagen Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne L.","family":"S\u00f8rensen","sequence":"additional","affiliation":[{"name":"Department of Public Health Section of Biostatistics University of Copenhagen Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin Gr\u00f8nneb\u00e6k","family":"Tolsgaard","sequence":"additional","affiliation":[{"name":"Copenhagen Academy for Medical Education and Simulation Copenhagen Denmark"},{"name":"Department of Clinical Medicine Faculty of Health and Medical Sciences University of Copenhagen Copenhagen Denmark"},{"name":"Department of Obstetrics and Gynecology Copenhagen University Hospital North Zealand Hiller\u00f8d Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,1,12]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"Royal College of Obstetricians & Gynaecologists.Small\u2010for\u2010Gestational\u2010Age Fetus Investigation and Management(Green\u2010top Guideline No. 31). Published online 2013. London: RCOG;2013."},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.15884"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.10150"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2018.02.008"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2016.06.043"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.puhe.2014.06.022"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.3109\/14767058.2011.600793"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.1806"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)00131-2"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.13148"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2009.11.023"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2019.01.227"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.17393"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2018.12.023"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2017.12.002"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/MLR.0b013e3182a048af"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-142-4-200502150-00008"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1975.tb00710.x"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(85)90298-4"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1996.tb14164.x"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.3109\/14767058.2014.964675"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.12313"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-3016.1997.d01-17.x"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dms044"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000266983.77458.71"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.03.027"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-2115(01)00496-1"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2012.03446.x"},{"volume-title":"Safety\u2010I and Safety\u2010II: The Past and Future of Safety Management","year":"2014","author":"Hollnagel E","key":"e_1_2_10_30_1"},{"key":"e_1_2_10_31_1","unstructured":"Danish Fetal Medicine Database. Annual report2015.http:\/\/www.dfms.dk\/images\/foetodatabase\/Arsrapport_FOTO_2015_final_anonymiseret"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1097\/00001888-200210001-00002"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2019.0096"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2010.1034"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1475-6773.2008.00918.x"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1097\/ACM.0000000000001964"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.13764"}],"container-title":["Acta Obstetricia et Gynecologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aogs.14048","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/aogs.14048","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aogs.14048","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T07:00:55Z","timestamp":1693551655000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/aogs.14048"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1,12]]},"references-count":36,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2021,5]]}},"alternative-id":["10.1111\/aogs.14048"],"URL":"https:\/\/doi.org\/10.1111\/aogs.14048","archive":["Portico"],"relation":{},"ISSN":["0001-6349","1600-0412"],"issn-type":[{"type":"print","value":"0001-6349"},{"type":"electronic","value":"1600-0412"}],"subject":[],"published":{"date-parts":[[2021,1,12]]},"assertion":[{"value":"2020-06-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-11-16","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-01-12","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}