{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T23:54:59Z","timestamp":1784850899027,"version":"3.55.0"},"reference-count":34,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2021,2,13]],"date-time":"2021-02-13T00:00:00Z","timestamp":1613174400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100010125","name":"Jalmari ja Rauha Ahokkaan S\u00e4\u00e4ti\u00f6","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010125","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002341","name":"Academy of Finland","doi-asserted-by":"publisher","award":["315921"],"award-info":[{"award-number":["315921"]}],"id":[{"id":"10.13039\/501100002341","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002341","name":"Academy of Finland","doi-asserted-by":"publisher","award":["321763"],"award-info":[{"award-number":["321763"]}],"id":[{"id":"10.13039\/501100002341","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006306","name":"Sigrid Jus\u00e9liuksen S\u00e4\u00e4ti\u00f6","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006306","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Endometriosis is a common gynecological condition causing chronic pain and infertility. Only limited data exist on body size during childhood and adolescence in affected women. A leaner body shape has been associated with endometriosis in adults. However, longitudinal follow\u2010up data from birth to adulthood are lacking. The aim of this study was to assess the association between body size and endometriosis from birth to age 46\u00a0years. We also performed in\u2010depth analysis of the endometriosis subtypes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and Methods<\/jats:title><jats:p>This was a population\u2010based study including 96% of the children born in Northern Finland in 1966. Endometriosis case identification was based on (a) the World Health Organization\u2019s International Statistical Classification of Diseases code documentation from national hospital discharge registers and (b) self\u2010reported diagnosis. A total of 348 women with endometriosis (203 in subtype analysis) and 3487 women without endometriosis were identified. Pregnancy, birth, and growth data up to adolescence were collected from welfare clinical records. Follow\u2010up data of the Northern Finland Birth Cohort 1966 were collected at ages 14, 31, and 46\u00a0years through postal questionnaires and clinical examinations and included height, weight, and waist and hip circumference measurements. The associations between endometriosis and body size were assessed using logistic regression models.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Body sizes in childhood and adolescence were comparable between women developing endometriosis and those not developing endometriosis. On average, the risk for endometriosis was 2% lower for every kilogram of weight (odds ratio [OR] 0.98, 95% CI 0.97\u20101.00) and 6% lower for every body mass index unit (OR 0.94, 95% CI 0.90\u20100.99) at age 31. By age 46, a lower risk for peritoneal endometriosis was observed with greater weight (OR 0.95, 95% CI 0.92\u20100.98), weight gain from age 14 to age 46\u00a0years (OR 0.97, 95% CI 0.93\u20101.00), body mass index (OR 0.90, 95% CI 0.82\u20100.98), waist circumference (OR 0.95, 95% CI 0.92\u20100.99), and waist\u2010hip ratio (OR 0.41, 95% CI 0.21\u20100.78).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study provides further evidence of the associations between endometriosis and body size and adiposity, specifically in women with peritoneal endometriosis. The associations are evident in adulthood but not in childhood or adolescence.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aogs.14090","type":"journal-article","created":{"date-parts":[[2021,2,7]],"date-time":"2021-02-07T13:05:16Z","timestamp":1612703116000},"page":"1248-1257","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Body size during adulthood, but not in childhood, associates with endometriosis, specifically in the peritoneal subtype\u2014population\u2010based life\u2010course data from birth to late fertile age"],"prefix":"10.1111","volume":"100","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7886-4042","authenticated-orcid":false,"given":"Henna\u2010Riikka","family":"Rossi","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Oulu University Hospital Oulu Finland"},{"name":"PEDEGO Research Unit &amp; Medical Research Center University of Oulu Oulu 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