{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T01:27:24Z","timestamp":1769909244601,"version":"3.49.0"},"reference-count":22,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100010434","name":"\u201cla Caixa\u201d Foundation","doi-asserted-by":"publisher","award":["LCF\/PR\/GN18\/10310003"],"award-info":[{"award-number":["LCF\/PR\/GN18\/10310003"]}],"id":[{"id":"10.13039\/100010434","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Our objective was to evaluate the perinatal outcome of selective termination of dichorionic twin pregnancies with discordant anomalies, according to gestational age at time of procedure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>Retrospective review of 147 dichorionic twin pregnancies referred to our Fetal Medicine Unit between 2003 and 2018 for selective termination. Gestational age at delivery, fetal loss, and overall and 28\u2010day post\u2010delivery survival rate<jats:bold>s<\/jats:bold>, were evaluated according to gestational age at time of procedure. Selective termination procedure was defined as early, intermediate, and late when performed before 18\u00a0weeks, between 18 and 23\u00a0weeks, and after 23\u00a0weeks, respectively. Kruskal\u2013Wallis and chi\u2010squared test were used to compare groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Overall survival at 28\u00a0days post\u2010delivery, pregnancy loss, and preterm delivery before 32\u00a0weeks of gestation rates were 93.4%, 6.9%, and 15.5%, respectively. When stratified by gestational age at procedure, intermediate selective termination was associated with a lower survival rate than early and late procedures (86% vs. 96.9% and 100%, respectively; <jats:italic>p\u00a0<\/jats:italic>=\u00a00.035), and a nonsignificant trend for higher pregnancy loss (12% vs. 3.1%). Preterm delivery before 32\u00a0weeks of gestation occurred in 27% of late procedures, which was significantly higher than in early (9.5%) and intermediate (18.2%) procedures.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Selective termination in dichorionic twin pregnancies with discordant fetal anomaly is associated with low pregnancy loss and preterm delivery rate, primarily when performed before 18\u00a0weeks. When legally possible, late procedures can be a good alternative, particularly in those cases diagnosed beyond the 18th week of gestation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aogs.14249","type":"journal-article","created":{"date-parts":[[2021,9,2]],"date-time":"2021-09-02T04:07:41Z","timestamp":1630555661000},"page":"2029-2035","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Perinatal outcome after selective termination in dichorionic twins discordant for congenital anomalies"],"prefix":"10.1111","volume":"100","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3935-1935","authenticated-orcid":false,"given":"Mar","family":"Bennasar","sequence":"first","affiliation":[{"name":"BCNatal, Barcelona Center for Maternal\u2010Fetal and Neonatal Medicine Hospital Cl\u00ednic and Hospital Sant Joan de D\u00e9u Barcelona Spain"},{"name":"August Pi i Sunyer Biomedical Research Institute (IDIBAPS) Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00falia","family":"Ponce","sequence":"additional","affiliation":[{"name":"BCNatal, Barcelona Center for Maternal\u2010Fetal and Neonatal Medicine Hospital Cl\u00ednic and Hospital Sant Joan de D\u00e9u Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ximena","family":"Torres","sequence":"additional","affiliation":[{"name":"BCNatal, Barcelona Center for Maternal\u2010Fetal and Neonatal Medicine Hospital Cl\u00ednic and Hospital Sant Joan de D\u00e9u Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olga","family":"G\u00f3mez","sequence":"additional","affiliation":[{"name":"BCNatal, Barcelona Center for Maternal\u2010Fetal and Neonatal Medicine Hospital Cl\u00ednic and Hospital Sant Joan de D\u00e9u Barcelona Spain"},{"name":"August Pi i Sunyer Biomedical Research Institute (IDIBAPS) Barcelona 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Research Institute (IDIBAPS) Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josep M.","family":"Mart\u00ednez","sequence":"additional","affiliation":[{"name":"BCNatal, Barcelona Center for Maternal\u2010Fetal and Neonatal Medicine Hospital Cl\u00ednic and Hospital Sant Joan de D\u00e9u Barcelona Spain"},{"name":"August Pi i Sunyer Biomedical Research Institute (IDIBAPS) Barcelona 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