{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T15:58:07Z","timestamp":1792166287250,"version":"4.4.0"},"reference-count":22,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,12,7]],"date-time":"2021-12-07T00:00:00Z","timestamp":1638835200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100009708","name":"Novo Nordisk Fonden","doi-asserted-by":"publisher","award":["NNFSA170030576"],"award-info":[{"award-number":["NNFSA170030576"]}],"id":[{"id":"10.13039\/501100009708","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Home management in general is considered to improve patient well\u2010being, patient involvement and cost\u2010effectiveness, for obstetric patients as well. But concerns regarding inclusion of intermediate\u2010 and high\u2010risk pregnant women are an issue and a limitation for clinical implementation. This retrospective study evaluated the outcome and safety of extended remote self\u2010monitoring of maternal and fetal health in intermediate\u2010 and high\u2010risk pregnancies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>The study reports on 400 singleton pregnancies complicated by preterm premature rupture of membranes (PPROM), fetal growth restriction, preeclampsia, gestational diabetes mellitus, high\u2010risk of preeclampsia, or a history of previous fetal or neonatal loss. Remote self\u2010monitoring was performed by pregnant women and included C\u2010reactive protein, non\u2010stress test by cardiotocography, temperature, blood pressure, heart rate, and a questionnaire concerning maternal and fetal wellbeing. Data were transferred to the hospital using a mobile device platform and evaluated by healthcare professionals. In case of non\u2010reassuring registrations, the pregnant women were invited for assessment at the hospital. Primary outcome was perinatal death. Secondary outcomes were other maternal and perinatal complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>No severe maternal complications were observed. Nine fetal or neonatal deaths occurred, all secondary to malformations, severe fetal growth restriction, extreme prematurity or lung hypoplasia in cases of PPROM before 24\u00a0weeks. Even in the latter group, fetal and neonatal survival was 78% (18\/23) and rose to 97% (60\/62) when PPROM occurred after a gestational age 23+6 weeks. None of the fetal or neonatal deaths were attributable to the home\u2010management setting.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Home\u2010monitoring including remote self\u2010monitoring of fetal and maternal well\u2010being in intermediate\u2010 and high\u2010risk pregnancies seems to be a safe alternative to inpatient or frequent outpatient care, which sets the stage for a new way of thinking of hospital care. The implementation process included staff training workshops and development of patient enrollment practice with clarification of expectations and responsibilities, which can be crucial to the results.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aogs.14294","type":"journal-article","created":{"date-parts":[[2021,12,8]],"date-time":"2021-12-08T05:03:55Z","timestamp":1638939835000},"page":"135-144","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":41,"title":["Home management by remote self\u2010monitoring in intermediate\u2010 and high\u2010risk pregnancies: A retrospective study of 400 consecutive women"],"prefix":"10.1111","volume":"101","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0342-0708","authenticated-orcid":false,"given":"Anne Rahbek","family":"Zizzo","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Aarhus University Hospital  Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lone","family":"Hvidman","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Aarhus University Hospital  Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jannie Dalby","family":"Salvig","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Aarhus University Hospital  Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lone","family":"Holst","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Aarhus University Hospital  Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9114-1164","authenticated-orcid":false,"given":"Morten","family":"Kyng","sequence":"additional","affiliation":[{"name":"Department of Computer Science Aarhus University  Aarhus Denmark"},{"name":"Health IT The Alexandra Institute  Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8517-4082","authenticated-orcid":false,"given":"Olav Bj\u00f8rn","family":"Petersen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Aarhus University Hospital  Aarhus Denmark"},{"name":"Department of Obstetrics Copenhagen University Hospital Rigshospitalet  Copenhagen Denmark"},{"name":"Department of Clinical Medicine University of Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,12,7]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.19041"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD008053.pub3"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijgo.12122"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jogc.2016.03.001"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/14767058.2017.1341482"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajo.12021"},{"key":"e_1_2_10_8_1","first-page":"61","article-title":"Preterm premature rupture of membranes: a randomized study of home versus hospital management","volume":"81","author":"Carlan SJ","year":"1993","journal-title":"Obstet Gynecol"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1084-628X(97)90117-9"},{"key":"e_1_2_10_10_1","first-page":"629","article-title":"Outcome and cost analysis of preterm premature rupture of membranes in an outpatient setting","volume":"2","author":"Martin D","year":"1996","journal-title":"Am J Man Care"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMp2003539"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1975.tb00710.x"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.117.10803"},{"key":"e_1_2_10_14_1","volume-title":"Antenatal corticosteroid","author":"Gustafson LW","year":"2018"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(03)00926-8"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12884-016-0813-3"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/jp.2010.11"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1004830"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.5582\/bst.2014.01058"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.13433"},{"key":"e_1_2_10_21_1","volume-title":"Klinisk Integreret Hjemmemonitorering (KIH). 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