{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T07:22:02Z","timestamp":1790493722247,"version":"4.1.0"},"reference-count":44,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2022,2,27]],"date-time":"2022-02-27T00:00:00Z","timestamp":1645920000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012519","name":"\u00c9cole des Hautes \u00c9tudes en Sant\u00e9 Publique","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012519","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100015397","name":"Minist\u00e8re de la Culture","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100015397","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009647","name":"Ministry of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009647","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003562","name":"Ministry of Environment","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003562","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001665","name":"Agence Nationale de la Recherche","doi-asserted-by":"publisher","award":["ANR\u201019\u2010COHO\u20100001"],"award-info":[{"award-number":["ANR\u201019\u2010COHO\u20100001"]}],"id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001665","name":"Agence Nationale de la Recherche","doi-asserted-by":"publisher","award":["ANR\u201011\u2010EQPX\u20100038"],"award-info":[{"award-number":["ANR\u201011\u2010EQPX\u20100038"]}],"id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Customized intrauterine growth charts are widely used for growth monitoring and research. They are based on three assumptions: (1) estimated fetal weight (EFW) has a normal distribution with a constant coefficient of variation at all gestational ages; (2) Hadlock\u2019s growth curve accurately describes the relation between EFW and gestational ages; (3) associations between EFW and the fetal and maternal characteristics included in the customization model (fetal sex, pre\u2010pregnancy weight, height, parity) are proportional throughout pregnancy. The aim of this study was to test whether these underlying assumptions are verified.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>Data came from (1) the French Longitudinal Study of Children (ELFE) cohort, which recruited births after 32\u00a0weeks' gestation in 349 maternity hospitals in France in 2011, and (2) the National Perinatal Survey, which included births from all French maternity hospitals in 2016. The study population included, respectively, 6\u2005920 and 8\u2005969 singleton non\u2010malformed term live births with data on customization characteristics and EFW. We computed the coefficient of variation by gestational age and then modeled the association of gestational age, maternal and fetal characteristics with EFW at the second and third trimester ultrasound and with birthweight using linear regression. To assess the proportionality of the impact of maternal and fetal characteristics, we computed the percent change in weight associated with these characteristics at these three time points.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The coefficient of variation was close to 12% at each gestational age, but EFW was not normally distributed, leading to small but systematic underestimation of fetuses under the 10th percentile. Weights representing the 50th and 10th percentiles based on Hadlock\u2019s growth trajectory were lower than observed or predicted weights. Most characteristics more strongly impacted weight at birth than during pregnancy. In the French Longitudinal study of Children (ELFE) cohort, boys were 1.8% (95% confidence interval [CI] 1.3\u20132.4) heavier than girls in the third trimester, whereas this percentage was 4.6% (95% CI 4.0\u20135.2) at birth. In the National Perinatal Survey, these percentages were 2.3% (95% CI 1.8\u20132.8) and 4.3% (95% CI 3.8\u20134.8).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>These results from two independent sources revealed discrepancies between routine clinical EFW data used for growth monitoring and the customized growth model\u2019s assumptions.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aogs.14335","type":"journal-article","created":{"date-parts":[[2022,2,28]],"date-time":"2022-02-28T06:25:30Z","timestamp":1646029530000},"page":"405-416","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Testing the assumptions of customized intrauterine growth charts using national birth studies"],"prefix":"10.1111","volume":"101","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7905-7098","authenticated-orcid":false,"given":"Alice","family":"Hocquette","sequence":"first","affiliation":[{"name":"CRESS, Obstetrical Perinatal and Pediatric Epidemiology Research Team, EPOP\u00e9, INSERM, INRA Universit\u00e9 de Paris  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2755-7322","authenticated-orcid":false,"given":"Isabelle","family":"Monier","sequence":"additional","affiliation":[{"name":"CRESS, Obstetrical Perinatal and Pediatric Epidemiology Research Team, EPOP\u00e9, INSERM, INRA Universit\u00e9 de Paris  Paris France"},{"name":"Department of Obstetrics and Gynecology, Antoine B\u00e9cl\u00e8re Hospital, AP\u2010HP University Paris Saclay  Clamart France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9367-8317","authenticated-orcid":false,"given":"B\u00e9atrice","family":"Blondel","sequence":"additional","affiliation":[{"name":"CRESS, Obstetrical Perinatal and Pediatric Epidemiology Research Team, EPOP\u00e9, INSERM, INRA Universit\u00e9 de Paris  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie\u2010No\u00eblle","family":"Dufourg","sequence":"additional","affiliation":[{"name":"Ined, Inserm, Joint Unit Elfe  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Heude","sequence":"additional","affiliation":[{"name":"Research Team on the Early Life Origins of Health (EAROH), Center for Research in Epidemiology and Statistics (CRESS), INSERM Universit\u00e9 de Paris  Villejuif France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9568-2969","authenticated-orcid":false,"given":"Jennifer","family":"Zeitlin","sequence":"additional","affiliation":[{"name":"CRESS, Obstetrical Perinatal and Pediatric Epidemiology Research Team, EPOP\u00e9, INSERM, INRA Universit\u00e9 de Paris  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,2,27]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.f108"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.6286"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(10)62233-7"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.c7087"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.17433"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.20414"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jgyn.2013.09.012"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2017.12.004"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000004251"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijgo.13522"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.1995.06030168.x"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2009.02143.x"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.1962"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.1993.03060395.x"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jgyn.2015.08.008"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2005.10.816"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1479-828X.2012.01441.x"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2017.12.011"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwq399"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.181.1.1887021"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.9006"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2001.00205.x"},{"key":"e_1_2_10_24_1","first-page":"565","article-title":"Customized versus population approach for evaluation of fetal overgrowth","volume":"30","author":"Costantine MM","year":"2013","journal-title":"Am J Perinatol"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.13394"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1159\/000497142"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1159\/000500453"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2431-9-58"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyz227"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jogoh.2017.09.002"},{"key":"e_1_2_10_31_1","unstructured":"Comite National Technique De L\u2019echographie De Depistage Prenatal. Rapport du Comit\u00e9 National Technique de l\u2019Echographie de D\u00e9pistage Pr\u00e9natal [Report of the National Technical Committee for Prenatal Screening Ultrasound].In French. Internet 2005 [cited 2019 Mar 12]. Available from:http:\/\/www.cfef.org\/archives\/lettres\/DocusCTE\/rapportCTE.pdf"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jgyn.2011.09.016"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(85)90298-4"},{"key":"e_1_2_10_34_1","first-page":"545","article-title":"Compte rendu du s\u00e9minaire de travail du Coll\u00e8ge fran\u00e7ais d\u2019\u00e9chographie f\u0153tal (CFEF) sur les r\u00e9f\u00e9rentiels et standards de biom\u00e9trie f\u0153tale. Juin 2017. [Report from the CFEF seminar on fetal biometry (June 2017)]. In French","volume":"45","author":"Coll\u00e8ge Fran\u00e7ais d\u2019\u00e9chographie F\u0153tale Cfef","year":"2017","journal-title":"Gynecol Obstet Fertil Senol"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jgyn.2015.01.006"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0258(19960330)15:6<647::AID-SIM184>3.0.CO;2-P"},{"key":"e_1_2_10_37_1","volume-title":"Stata statistical software: Release 14","author":"StataCorp","year":"2015"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.4067"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11121-007-0070-9"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2015.06.021"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1515\/jpm-2018-0219"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.1111\/ppe.12041"},{"key":"e_1_2_10_43_1","first-page":"1S30","article-title":"Les m\u00e9canismes d\u2019action du tabac Sur le cerveau en d\u00e9veloppement. [Mechanisms of action of tobacco smoke on the developing brain]. In French.","volume":"32","author":"Gressens P","year":"2003","journal-title":"J Gynecol Obstet Biol Reprod"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0021932016000493"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1471-0528.2003.02371.x"}],"container-title":["Acta Obstetricia et Gynecologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aogs.14335","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/aogs.14335","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aogs.14335","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,12]],"date-time":"2025-03-12T16:07:05Z","timestamp":1741795625000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/aogs.14335"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2,27]]},"references-count":44,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022,4]]}},"alternative-id":["10.1111\/aogs.14335"],"URL":"https:\/\/doi.org\/10.1111\/aogs.14335","archive":["Portico"],"relation":{},"ISSN":["0001-6349","1600-0412"],"issn-type":[{"value":"0001-6349","type":"print"},{"value":"1600-0412","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,2,27]]},"assertion":[{"value":"2021-09-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-01-22","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-02-27","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}