{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T18:35:41Z","timestamp":1785868541340,"version":"3.56.0"},"reference-count":34,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,10,12]],"date-time":"2022-10-12T00:00:00Z","timestamp":1665532800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The etiology of lower\u2010limb neurological deficit after vaginal delivery remains poorly understood. The objective herein was to identify factors associated with this maternal nerve injury after vaginal delivery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>A single\u2010center, case\u2013control (matching 1:4) study. Cases were women with a lower\u2010limb neurological deficit that appeared immediately after vaginal delivery. Controls were randomly selected women who gave birth vaginally during the same period, without any deficit. Finally, to assess the rates of factors associated with these deficits, we studied them using a randomly selected 5% sample of the population with vaginal deliveries.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>During the 30\u2010month study period, 31 cases were identified among 10\u00a0333 women who gave birth vaginally (0.3%, 95% CI 0.20\u20130.43); 124 controls were also included. After logistic regression, the presence of a neurological deficit after delivery was associated with second\u2010stage labor duration (per hour odds ratio [OR] 3.67, 95% CI 2.09\u20136.44; OR per standard deviation increase 2.73, 95% CI 1.75\u20134.25, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and instrumental delivery (OR\u00a0=\u00a03.24, 95% CI 1.29\u20138.14, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.012), with no interaction effect (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.56). Extrapolation of these factors to a 5% sample of the overall population of women with vaginal births showed that the rate of these deficits would be very low for women with second\u2010stage labor lasting up to 90\u2009min without instrumental delivery (0.05%) but increased to 1.52% when these factors were combined (OR 33.1, 95% CI 9.4\u2013116.9).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Following vaginal delivery, the onset of a neurological deficit is principally associated with the duration of second\u2010stage labor and instrumental delivery.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aogs.14441","type":"journal-article","created":{"date-parts":[[2022,10,13]],"date-time":"2022-10-13T05:39:37Z","timestamp":1665639577000},"page":"51-58","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Factors associated with a maternal lower\u2010limb neurological deficit after vaginal delivery"],"prefix":"10.1111","volume":"102","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2558-1839","authenticated-orcid":false,"given":"Alexane","family":"Tournier","sequence":"first","affiliation":[{"name":"Women and Newborn Mother Unit Centre Hospitalier Universitaire de Lille, Universit\u00e9 Lille  Lille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne Cecile","family":"Doremieux","sequence":"additional","affiliation":[{"name":"Women and Newborn Mother Unit Centre Hospitalier Universitaire de Lille, Universit\u00e9 Lille  Lille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elodie","family":"Drumez","sequence":"additional","affiliation":[{"name":"EA 2694, METRICS, Evaluation of Health Technologies and Medical Practices Universit\u00e9 Lille  Lille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julien","family":"Labreuche","sequence":"additional","affiliation":[{"name":"EA 2694, METRICS, Evaluation of Health Technologies and Medical Practices Universit\u00e9 Lille  Lille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7ois","family":"Cassim","sequence":"additional","affiliation":[{"name":"Neuro\u2010sciences Unit, Clinical Neuro\u2010physiology Centre Hospitalier Universitaire de Lille, Universit\u00e9 Lille  Lille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7331-8528","authenticated-orcid":false,"given":"Max","family":"Gonzales","sequence":"additional","affiliation":[{"name":"Anesthesia\u2010Resuscitation Unit Centre Hospitalier Universitaire de Lille, Universit\u00e9 Lille  Lille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2105-9784","authenticated-orcid":false,"given":"Charles","family":"Garabedian","sequence":"additional","affiliation":[{"name":"Women and Newborn Mother Unit Centre Hospitalier Universitaire de Lille, 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