{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T11:55:02Z","timestamp":1792151702553,"version":"4.4.0"},"reference-count":47,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,10,20]],"date-time":"2022-10-20T00:00:00Z","timestamp":1666224000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Human pregnancy is considered term from 37+0\/7 to 41+6\/7\u2009weeks. Within this range, both maternal, fetal and neonatal risks may vary considerably. This study investigates how gestational age per week is related to the components of perinatal mortality and parameters of adverse neonatal and maternal outcome at term.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and Methods<\/jats:title><jats:p>A registry\u2010based study was made of all singleton term pregnancies in the Netherlands from January 2014 to December 2017. Stillbirth and early neonatal mortality, as components of perinatal mortality, were defined as primary outcomes; adverse neonatal and maternal events as secondary outcomes. Neonatal adverse outcomes included birth trauma, 5\u2010minute Apgar score \u22643, asphyxia, respiratory insufficiency, neonatal intensive care unit admission and composite neonatal outcome. Maternal adverse outcomes included instrumental vaginal birth, emergency cesarean section, obstetric anal sphincter injury, postpartum hemorrhage, hypertensive disorders of pregnancy and composite maternal outcome. The primary outcomes were evaluated by comparing weekly prospective risks of stillbirth and neonatal death using a fetuses\u2010at\u2010risk approach. Secondly, odds ratios (OR) for perinatal mortality, adverse neonatal and maternal outcome using a births\u2010based approach were compared for each gestational week with all births occurring after that week.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Data of 581\u2009443 births were analyzed. At 37, 38, 39, 40, 41 and 42\u2009weeks, the respective weekly prospective risks of stillbirth were 0.015%, 0.022%, 0.031%, 0.036%, 0.069% and 0.081%; the respective weekly prospective risks of early neonatal death were 0.051%, 0.047%, 0.032%, 0.031%, 0.039% and 0.035%. The OR for adverse neonatal outcomes were the lowest at 39 and 40\u2009weeks. The OR for adverse maternal outcomes, including operative birth, continuously increased with each gestational week.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The prospective risk of early neonatal death for babies born at 39\u2009weeks is lower than the risk of stillbirth in pregnancies continuing beyond 39+6\/7\u2009weeks. Birth at 39\u2009weeks was associated with the best combined neonatal and maternal outcome, fewer operative births and fewer maternal and neonatal adverse outcomes compared with pregnancies continuing beyond 39\u2009weeks. This information with appropriate perspectives should be included when counseling term pregnant women.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aogs.14467","type":"journal-article","created":{"date-parts":[[2022,10,20]],"date-time":"2022-10-20T09:33:47Z","timestamp":1666258427000},"page":"82-91","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Perinatal mortality and neonatal and maternal outcome per gestational week in term pregnancies: A registry\u2010based study"],"prefix":"10.1111","volume":"102","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8482-5138","authenticated-orcid":false,"given":"J\u00e9r\u00f4me","family":"Cornette","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Fetal Medicine Erasmus MC  Rotterdam the\u00a0Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4887-3930","authenticated-orcid":false,"given":"Catharina J.","family":"van der Stok","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Fetal Medicine Erasmus MC  Rotterdam the\u00a0Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9474-6895","authenticated-orcid":false,"given":"Irwin K. M.","family":"Reiss","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics Erasmus MC  Rotterdam the\u00a0Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ren\u00e9 F.","family":"Kornelisse","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics Erasmus MC  Rotterdam the\u00a0Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eline","family":"van der Wilk","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Fetal Medicine Erasmus MC  Rotterdam the\u00a0Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8801-5546","authenticated-orcid":false,"given":"Arie","family":"Franx","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Fetal Medicine Erasmus MC  Rotterdam the\u00a0Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3172-5672","authenticated-orcid":false,"given":"Yves","family":"Jacquemyn","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology University Hospital Antwerp UZA  Edegem Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6658-9274","authenticated-orcid":false,"given":"Eric A. P.","family":"Steegers","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Fetal Medicine Erasmus MC  Rotterdam the\u00a0Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0897-0709","authenticated-orcid":false,"given":"Loes C. M.","family":"Bertens","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Fetal Medicine Erasmus MC  Rotterdam the\u00a0Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,10,20]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clp.2018.01.004"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.c7087"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)60736-4"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.14435"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1003436"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.l344"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.l6131"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e3182a6a4d0"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2019.02.046"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1800566"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.e2838"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1002838"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)00954-X"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)01020-X"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2011.1823"},{"issue":"621","key":"e_1_2_11_17_1","first-page":"e1","article-title":"US term stillbirth rates and the 39\u2010week rule: a cause for concern?","volume":"214","author":"Nicholson JM","year":"2016","journal-title":"Am J Obstet Gynecol"},{"key":"e_1_2_11_18_1","unstructured":"Royal College of Obstetricians and Gynaecologists.Late intrauterine fetal death and stillbirth.Green\u2013top Guideline 2010. 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