{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T17:43:34Z","timestamp":1791999814515,"version":"4.4.0"},"reference-count":28,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,12,9]],"date-time":"2022-12-09T00:00:00Z","timestamp":1670544000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Induction of labor is often performed to prevent adverse perinatal and maternal outcomes, and has become increasingly common. We studied whether changes in prevalence of labor induction in gestational weeks 37\u201342\u2009weeks were accompanied by changes in adverse pregnancy outcomes or mode of delivery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>We used data from the Medical Birth Registry of Norway, and included all singleton births in gestational weeks 37\u201342 in Norway, 1999\u20132019 (<jats:italic>n<\/jats:italic>\u00a0=\u00a01\u00a0127\u2009945). We calculated the prevalence of labor induction and outcome measures according to year of birth. We repeated these calculations for each gestational week at birth.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The prevalence of labor induction increased from 9.7% to 25.9%, and the increase was particularly high in gestational week 41. A modest decline in fetal deaths was observed in all gestational weeks, except gestational week 41. The overall decline was from 0.18% in 1999\u20132004 to 0.13% during 2015\u20132019. There were no overall changes in other perinatal outcomes. The prevalence of postpartum hemorrhage \u2265500\u2009ml increased from 11.4% in 1999 to 30.1% in 2019, and operative deliveries increased slightly. The prevalence of acute cesarean section increased from 6.5% to 9.3%, whereas vacuum and\/or forceps assisted deliveries increased from 7.8% to 10.4%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>A high increase in labor inductions was accompanied by a modest decline in fetal deaths, but no decline in other adverse perinatal outcomes. In settings where the prevalence of adverse perinatal outcomes is low, the beneficial effect of increased use of labor induction may not outweigh the side effects or the costs.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aogs.14489","type":"journal-article","created":{"date-parts":[[2022,12,10]],"date-time":"2022-12-10T06:11:21Z","timestamp":1670652681000},"page":"158-173","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Is the increasing prevalence of labor induction accompanied by changes in pregnancy outcomes? An observational study of all singleton births at gestational weeks 37\u201342 in Norway during 1999\u20132019"],"prefix":"10.1111","volume":"102","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4708-3267","authenticated-orcid":false,"given":"Camilla","family":"Haavaldsen","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Akershus University Hospital  L\u00f8renskog Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nils\u2010Halvdan","family":"Morken","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Haukeland University Hospital  Bergen Norway"},{"name":"Department of Clinical Science University of Bergen  Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ola Didrik","family":"Saugstad","sequence":"additional","affiliation":[{"name":"Department of Pediatric Research University of Oslo  Oslo Norway"},{"name":"Ann and Robert H. Lurie Children's Hospital of Chicago  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2756-1583","authenticated-orcid":false,"given":"Anne","family":"Eskild","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Akershus University Hospital  L\u00f8renskog Norway"},{"name":"Institute of Clinical Medicine, University of Oslo  Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,12,9]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2010.07.014"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/1475-6773.12721"},{"key":"e_1_2_10_4_1","article-title":"Induction of labour at or beyond 37\u2009weeks' gestation","volume":"7","author":"Middleton P","year":"2020","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.l6131"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.l344"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.13113"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.11124\/JBISRIR-2017-003587"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0412.2000.079006435.x"},{"key":"e_1_2_10_10_1","unstructured":"Open database: Norwegian Institute of Public Health [Internet].Medical Birth Registry of Norway (MBRN)[Internet] [Cited2022Sept 1]. Available fromhttp:\/\/statistikk.fhi.no\/mfr\/"},{"key":"e_1_2_10_11_1","unstructured":"Norwegian Directorate of Health and Social Affairs [Internet].A National Clinical Guideline for Antenatal Care[cited2022Sept 1]. Available fromhttps:\/\/www.helsedirektoratet.no\/retningslinjer\/svangerskapsomsorgen"},{"key":"e_1_2_10_12_1","unstructured":"OppegaardKS D\u00f6glM SunC HillS Ween\u2010VelkenM S\u00f8rbyeIK.Induksjon\/igangsettelse av f\u00f8dsel \u2013 Modning av cervix\/livmorhalsen f\u00f8r f\u00f8dsel. [Induction\/Initiation of Labor \u2013 Maturation of the Cervix\/Uterine Neck before Birth]. Norsk Gynekologisk Forening Veileder i f\u00f8dselshjelp2020. ePub. ISBN 978\u201382\u2013692382\u20100\u20104. [Cited 2022 Sept 1]. Available from:https:\/\/www.legeforeningen.no\/foreningsledd\/fagmed\/norsk\u2010gynekologisk\u2010forening\/veiledere\/veileder\u2010i\u2010fodselshjelp\/induksjonigangsettelse\u2010av\u2010fodsel\u2010modning\u2010av\u2010cervixlivmorhalsen\u2010for\u2010fodsel\/"},{"key":"e_1_2_10_13_1","unstructured":"MorkenNH HaavaldsenC HeimstadR MurzakanovaG StokkeAMOvertidig svangerskap. Norsk gynekologisk forening Veileder i f\u00f8dselshjelp(2020). ePub. ISBN 978\u201382\u2013692382\u20100\u20104. [Cited 2022 Sept 1]. Available from:https:\/\/www.legeforeningen.no\/foreningsledd\/fagmed\/norsk\u2010gynekologisk\u2010forening\/veiledere\/veileder\u2010i\u2010fodselshjelp\/overtidig\u2010svangerskap\/"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc10-0719"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.preghy.2018.05.004"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.13948"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1213\/00000539-195301000-00041"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.preghy.2022.02.001"},{"key":"e_1_2_10_19_1","unstructured":"Open database: Norwegian Institute of Public Health [Internet].Norwegian Registry of Pregnancy Termination[Cited 2022 Jan 19]. Available at: statistikkbank.fhi.no\/abort\/."},{"key":"e_1_2_10_20_1","volume-title":"Fetal Death: High Maternal Age at Childbirth and the Placenta [Dissertation]","author":"Haavaldsen C","year":"2014"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/EDE.0000000000000564"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2010.310"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2020.01.002"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2016.10.017"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1800566"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2009.06.007"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016349.2010.514324"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2019.02.017"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.16929"}],"container-title":["Acta Obstetricia et Gynecologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aogs.14489","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/aogs.14489","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aogs.14489","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,5]],"date-time":"2025-04-05T10:44:10Z","timestamp":1743849850000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/aogs.14489"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,9]]},"references-count":28,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,2]]}},"alternative-id":["10.1111\/aogs.14489"],"URL":"https:\/\/doi.org\/10.1111\/aogs.14489","archive":["Portico"],"relation":{},"ISSN":["0001-6349","1600-0412"],"issn-type":[{"value":"0001-6349","type":"print"},{"value":"1600-0412","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,9]]},"assertion":[{"value":"2022-07-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-11-17","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-12-09","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}